mTORC1 activation decreases autophagy in aging and idiopathic pulmonary fibrosis and contributes to apoptosis resistance in IPF fibroblasts
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Title
mTORC1 activation decreases autophagy in aging and idiopathic pulmonary fibrosis and contributes to apoptosis resistance in IPF fibroblasts
Authors
Keywords
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Journal
AGING CELL
Volume 15, Issue 6, Pages 1103-1112
Publisher
Wiley
Online
2016-08-27
DOI
10.1111/acel.12514
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Note: Only part of the references are listed.- Matrix metalloproteinase (MMP)-19-deficient fibroblasts display a profibrotic phenotype
- (2015) Paul Jara et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Blue Journal Conference. Aging and Susceptibility to Lung Disease
- (2015) Victor J. Thannickal et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis
- (2015) Sandra Cabrera et al. Autophagy
- Autophagy exacerbates caspase-dependent apoptotic cell death after short times of starvation
- (2015) Paolo Mattiolo et al. BIOCHEMICAL PHARMACOLOGY
- Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs
- (2015) Ruping Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The functional and pathologic relevance of autophagy proteases
- (2015) Álvaro F. Fernández et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy: a druggable process that is deregulated in aging and human disease
- (2015) Guido Kroemer JOURNAL OF CLINICAL INVESTIGATION
- MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation
- (2015) Remi-Martin Laberge et al. NATURE CELL BIOLOGY
- Revealing the Pathogenic and Aging-related Mechanisms of the Enigmatic Idiopathic Pulmonary Fibrosis. An Integral Model
- (2014) Moisés Selman et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Metabolic Control of Autophagy
- (2014) Lorenzo Galluzzi et al. CELL
- Geroscience: Linking Aging to Chronic Disease
- (2014) Brian K. Kennedy et al. CELL
- PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis
- (2014) Marta Bueno et al. JOURNAL OF CLINICAL INVESTIGATION
- Self-consumption: the interplay of autophagy and apoptosis
- (2014) Guillermo Mariño et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- IPF Fibroblasts Are Desensitized to Type I Collagen Matrix-Induced Cell Death by Suppressing Low Autophagy via Aberrant Akt/mTOR Kinases
- (2014) Richard Seonghun Nho et al. PLoS One
- Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance
- (2014) L. Hecker et al. Science Translational Medicine
- Autophagy in ageing and ageing-associated diseases
- (2013) Li-qiang He et al. ACTA PHARMACOLOGICA SINICA
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Rapalogs and mTOR inhibitors as anti-aging therapeutics
- (2013) Dudley W. Lamming et al. JOURNAL OF CLINICAL INVESTIGATION
- mTOR is a key modulator of ageing and age-related disease
- (2013) Simon C. Johnson et al. NATURE
- Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
- (2013) Tasha E Fingerlin et al. NATURE GENETICS
- Insufficient autophagy in idiopathic pulmonary fibrosis
- (2012) Jun Araya et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Hormesis
- (2012) Soledad Matus et al. Autophagy
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- Decreased expression of autophagic beclin 1 protein in idiopathic pulmonary fibrosis fibroblasts
- (2012) Alberto Ricci et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Autophagy modulation as a potential therapeutic target for diverse diseases
- (2012) David C. Rubinsztein et al. NATURE REVIEWS DRUG DISCOVERY
- The telomere syndromes
- (2012) Mary Armanios et al. NATURE REVIEWS GENETICS
- Autophagy in Idiopathic Pulmonary Fibrosis
- (2012) Avignat S. Patel et al. PLoS One
- An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management
- (2011) Ganesh Raghu et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Autophagy and Aging
- (2011) David C. Rubinsztein et al. CELL
- Idiopathic pulmonary fibrosis
- (2011) Talmadge E King et al. LANCET
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
- (2010) Shunsuke Minagawa et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Aging and Interstitial Lung Diseases: Unraveling an Old Forgotten Player in the Pathogenesis of Lung Fibrosis
- (2010) Moisés Selman et al. SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
- Regulation Mechanisms and Signaling Pathways of Autophagy
- (2009) Congcong He et al. Annual Review of Genetics
- Anti- and pro-tumor functions of autophagy
- (2009) Eugenia Morselli et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
- (2009) Morris E Feldman et al. PLOS BIOLOGY
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