Autophagy and the unfolded protein response promote profibrotic effects of TGF-β1 in human lung fibroblasts

Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis

(2017) Ana L. Mora et al.   JOURNAL OF CLINICAL INVESTIGATION

Endoplasmic reticulum stress-mediated induction of SESTRIN 2 potentiates cell survival

(2016) Svetlana Saveljeva et al.   Oncotarget

Inhibition of autophagy inhibits the conversion of cardiac fibroblasts to cardiac myofibroblasts

(2016) Shivika S. Gupta et al.   Oncotarget

Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1

(2015) Meredith L. Sosulski et al.   AGING CELL

Autophagy in airway diseases: a new frontier in human asthma?

(2015) A. A. Zeki et al.   ALLERGY

Reduced FoxO3a expression causes low autophagy in idiopathic pulmonary fibrosis fibroblasts on collagen matrices

(2015) Jintaek Im et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Three-Dimensional Culture and FGF Signaling Drive Differentiation of Murine Pluripotent Cells to Distal Lung Epithelial Cells

(2015) Emily Fox et al.   STEM CELLS AND DEVELOPMENT

Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts

(2015) S Ghavami et al.   Cell Death & Disease

New Therapeutic Targets in Idiopathic Pulmonary Fibrosis. Aiming to Rein in Runaway Wound-Healing Responses

(2014) Neil Ahluwalia et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Amino acids and autophagy: cross-talk and co-operation to control cellular homeostasis

(2014) Bernadette Carroll et al.   AMINO ACIDS

Airway mesenchymal cell death by mevalonate cascade inhibition: Integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins

(2014) Saeid Ghavami et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy and Heart Disease: Implications for Cardiac Ischemia- Reperfusion Damage

(2014) S. Ghavami et al.   CURRENT MOLECULAR MEDICINE

The effect of transforming growth factor β1 on the crosstalk between autophagy and apoptosis in the annulus fibrosus cells under serum deprivation

(2014) Bin-Bin Ni et al.   CYTOKINE

Transforming growth factor-β1 reduces apoptosis via autophagy activation in hepatic stellate cells

(2014) MEI-YA FU et al.   Molecular Medicine Reports

miR-29b as a Therapeutic Agent for Angiotensin II-induced Cardiac Fibrosis by Targeting TGF-β/Smad3 signaling

(2014) Yang Zhang et al.   MOLECULAR THERAPY

mTOR and autophagy: A dynamic relationship governed by nutrients and energy

(2014) E.A. Dunlop et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Modifiers of TGF-β1 effector function as novel therapeutic targets of pulmonary fibrosis

(2014) Chang-Min Lee et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Increased Expression of Endoplasmic Reticulum Stress and Unfolded Protein Response Genes in Peripheral Blood Mononuclear Cells From Patients With Limited Cutaneous Systemic Sclerosis and Pulmonary Arterial Hypertension

(2013) Stefania Lenna et al.   ARTHRITIS AND RHEUMATISM

Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b

(2013) Bo Wang et al.   KIDNEY INTERNATIONAL

Disruption of microRNA Biogenesis Confers Resistance to ER Stress-Induced Cell Death Upstream of the Mitochondrion

(2013) Karen Cawley et al.   PLoS One

Regulation of Autophagy by TGF-β: Emerging Role in Kidney Fibrosis

(2013) Yan Ding et al.   SEMINARS IN NEPHROLOGY

Self-Eating: Friend or Foe? The Emerging Role of Autophagy in Idiopathic Pulmonary Fibrosis

(2013) George A. Margaritopoulos et al.   Biomed Research International

Transforming growth factor-beta1 in inflammatory airway disease: a key for understanding inflammation and remodeling

(2012) Y. C. Yang et al.   ALLERGY

STAT3-Mediated Signaling Dysregulates Lung Fibroblast-Myofibroblast Activation and Differentiation in UIP/IPF

(2012) Dmitri V. Pechkovsky et al.   AMERICAN JOURNAL OF PATHOLOGY

Insufficient autophagy in idiopathic pulmonary fibrosis

(2012) Jun Araya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

ATG5, autophagy and lung function in asthma

(2012) Audrey Poon et al.   Autophagy

Regulation of TGF-β storage and activation in the human idiopathic pulmonary fibrosis lung

(2012) Outi Leppäranta et al.   CELL AND TISSUE RESEARCH

Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues

(2012) Virginia Hernández–Gea et al.   GASTROENTEROLOGY

Organ fibrosis inhibited by blocking transforming growth factor-β signaling via peroxisome proliferator-activated receptor γ agonists

(2012) Yi-Lei Deng et al.   Hepatobiliary & Pancreatic Diseases International

Autophagy Promotes Intracellular Degradation of Type I Collagen Induced by Transforming Growth Factor (TGF)-β1

(2012) Sung Il Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGF- 1-Containing Exosomes from Injured Epithelial Cells Activate Fibroblasts to Initiate Tissue Regenerative Responses and Fibrosis

(2012) F. T. Borges et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autophagy in Idiopathic Pulmonary Fibrosis

(2012) Avignat S. Patel et al.   PLoS One

Novel non-canonical TGF-β signaling networks: Emerging roles in airway smooth muscle phenotype and function

(2012) Behzad Yeganeh et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle

(2011) Saeid Ghavami et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Autophagy

(2011) Jeffrey A. Haspel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Multiple ways to die: Delineation of the unfolded protein response and apoptosis induced by Surfactant Protein C BRICHOS mutants

(2011) Jean Ann Maguire et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

TGF-β-induced epithelial-mesenchymal transition of A549 lung adenocarcinoma cells is enhanced by pro-inflammatory cytokines derived from RAW 264.7 macrophage cells

(2011) Mikiko Kawata et al.   JOURNAL OF BIOCHEMISTRY

Potent and Selective Inhibitors of the Inositol-requiring Enzyme 1 Endoribonuclease

(2011) Kori Volkmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atrial Fibrillation and Atrial Fibrosis

(2011) Alex Y Tan et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53

(2011) Saeid Ghavami et al.   PLoS One

Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs

(2011) W. E. Lawson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Lung Parenchyma but Not Proximal Bronchi Produces Fibroblasts with Enhanced TGF-β Signaling and α-SMA Expression

(2010) Dmitri V. Pechkovsky et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Role of Transforming Growth Factor–β in Airway Remodeling in Asthma

(2010) Rabih Halwani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c

(2010) Saeid Ghavami et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Strategies for treating idiopathic pulmonary fibrosis

(2010) R. M. du Bois   NATURE REVIEWS DRUG DISCOVERY

TACE antagonists blocking ACE2 shedding caused by the spike protein of SARS-CoV are candidate antiviral compounds

(2009) Shiori Haga et al.   ANTIVIRAL RESEARCH

Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection

(2008) William E. Lawson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY