Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells
Authors
Keywords
-
Journal
Autophagy
Volume -, Issue -, Pages 1-14
Publisher
Informa UK Limited
Online
2019-02-20
DOI
10.1080/15548627.2019.1569912
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Paracrine roles of cellular senescence in promoting tumourigenesis
- (2018) Jose Mario Gonzalez-Meljem et al. BRITISH JOURNAL OF CANCER
- Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species
- (2017) J Manent et al. ONCOGENE
- The relationship between tumour budding, the tumour microenvironment and survival in patients with primary operable colorectal cancer
- (2016) Hester C van Wyk et al. BRITISH JOURNAL OF CANCER
- EMT: 2016
- (2016) M. Angela Nieto et al. CELL
- Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells
- (2016) Jessie Yanxiang Guo et al. GENES & DEVELOPMENT
- Autophagy and epithelial–mesenchymal transition: an intricate interplay in cancer
- (2016) Mila Gugnoni et al. Cell Death & Disease
- Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells
- (2015) Myriam Catalano et al. Molecular Oncology
- Autophagy regulates hepatocyte identity and epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions promoting Snail degradation
- (2015) G Grassi et al. Cell Death & Disease
- Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells
- (2015) Wenjie Qin et al. Oncotarget
- Targeting Autophagy Addiction in Cancer
- (2015) Joseph D. Mancias et al. Oncotarget
- Autophagic cell death unraveled: Pharmacological inhibition of apoptosis and autophagy enables necrosis
- (2014) Eileen White Autophagy
- Autophagy functions on EMT in gastrulation of avian embryo
- (2014) Wen-Hui Lu et al. CELL CYCLE
- ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1
- (2014) Yihua Wang et al. NATURE CELL BIOLOGY
- Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial–mesenchymal transition
- (2013) Jun Li et al. CARCINOGENESIS
- Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
- (2013) J. Y. Guo et al. GENES & DEVELOPMENT
- p53 status determines the role of autophagy in pancreatic tumour development
- (2013) Mathias T. Rosenfeldt et al. NATURE
- Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
- (2013) J. Gao et al. Science Signaling
- VHL-Regulated MiR-204 Suppresses Tumor Growth through Inhibition of LC3B-Mediated Autophagy in Renal Clear Cell Carcinoma
- (2012) Olga Mikhaylova et al. CANCER CELL
- KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma
- (2012) Jianhua Ling et al. CANCER CELL
- Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1
- (2012) Oscar H. Ocaña et al. CANCER CELL
- Spatiotemporal Regulation of Epithelial-Mesenchymal Transition Is Essential for Squamous Cell Carcinoma Metastasis
- (2012) Jeff H. Tsai et al. CANCER CELL
- DEDD Interacts with PI3KC3 to Activate Autophagy and Attenuate Epithelial-Mesenchymal Transition in Human Breast Cancer
- (2012) Q. Lv et al. CANCER RESEARCH
- Tumor-Stroma Ratio Is an Independent Predictor for Survival in Esophageal Squamous Cell Carcinoma
- (2012) kai Wang et al. Journal of Thoracic Oncology
- Autophagy modulation as a potential therapeutic target for diverse diseases
- (2012) David C. Rubinsztein et al. NATURE REVIEWS DRUG DISCOVERY
- Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK
- (2012) A Avivar-Valderas et al. ONCOGENE
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Punctate LC3B Expression Is a Common Feature of Solid Tumors and Associated with Proliferation, Metastasis, and Poor Outcome
- (2011) R. Lazova et al. CLINICAL CANCER RESEARCH
- Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night
- (2011) Robin Mathew et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Pancreatic cancers require autophagy for tumor growth
- (2011) S. Yang et al. GENES & DEVELOPMENT
- Oncogenic Ras-Induced Expression of Noxa and Beclin-1 Promotes Autophagic Cell Death and Limits Clonogenic Survival
- (2011) Mohamed Elgendy et al. MOLECULAR CELL
- Control of autophagy as a therapy for neurodegenerative disease
- (2011) Harry Harris et al. Nature Reviews Neurology
- Response and Resistance to NF- B Inhibitors in Mouse Models of Lung Adenocarcinoma
- (2011) W. Xue et al. Cancer Discovery
- Requirement of the NF-κB Subunit p65/RelA for K-Ras–Induced Lung Tumorigenesis
- (2010) Daniela S. Bassères et al. CANCER RESEARCH
- TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype
- (2010) Gianluca Storci et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
- (2010) Rebecca Lock et al. MOLECULAR BIOLOGY OF THE CELL
- Critical role for transcriptional repressor Snail2 in transformation by oncogenic RAS in colorectal carcinoma cells
- (2010) Y Wang et al. ONCOGENE
- p62 at the Crossroads of Autophagy, Apoptosis, and Cancer
- (2009) Jorge Moscat et al. CELL
- Autophagy Suppresses Tumorigenesis through Elimination of p62
- (2009) Robin Mathew et al. CELL
- The Double-Edged Sword of Autophagy Modulation in Cancer
- (2009) E. White et al. CLINICAL CANCER RESEARCH
- Autophagy mediates the mitotic senescence transition
- (2009) A. R.J. Young et al. GENES & DEVELOPMENT
- PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation
- (2009) Kazuhiro Nakamura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Role for Ubiquitin in Selective Autophagy
- (2009) Vladimir Kirkin et al. MOLECULAR CELL
- Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma
- (2009) Etienne Meylan et al. NATURE
- The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis
- (2008) Angeles Duran et al. CANCER CELL
- Control of autophagy by oncogenes and tumor suppressor genes
- (2008) M C Maiuri et al. CELL DEATH AND DIFFERENTIATION
- NF-κB and epithelial to mesenchymal transition of cancer
- (2008) Chengyin Min et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Ras oncogenes: split personalities
- (2008) Antoine E. Karnoub et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started