Structural visualization of key steps in human transcription initiation

Transcription initiation by human RNA polymerase II visualized at single-molecule resolution

(2012) A. Revyakin et al.   GENES & DEVELOPMENT

Structure and function of the initially transcribing RNA polymerase II–TFIIB complex

(2012) Sarah Sainsbury et al.   NATURE

Architecture of the RNA polymerase II preinitiation complex and mechanism of ATP-dependent promoter opening

(2012) Sebastian Grünberg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Subunit architecture of general transcription factor TFIIH

(2012) B. J. Gibbons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opening and Closing of the Bacterial RNA Polymerase Clamp

(2012) A. Chakraborty et al.   SCIENCE

The Initiation Factor TFE and the Elongation Factor Spt4/5 Compete for the RNAP Clamp during Transcription Initiation and Elongation

(2011) Dina Grohmann et al.   MOLECULAR CELL

Structural basis of RNA polymerase II backtracking, arrest and reactivation

(2011) Alan C. M. Cheung et al.   NATURE

Molecular Architecture of the Human Mediator–RNA Polymerase II–TFIIF Assembly

(2011) Carrie Bernecky et al.   PLOS BIOLOGY

Conformational flexibility of RNA polymerase III during transcriptional elongation

(2010) Carlos Fernández-Tornero et al.   EMBO JOURNAL

Architecture of the RNA polymerase II–TFIIF complex revealed by cross-linking and mass spectrometry

(2010) Zhuo Angel Chen et al.   EMBO JOURNAL

Position of the general transcription factor TFIIF within the RNA polymerase II transcription preinitiation complex

(2009) Jesse Eichner et al.   EMBO JOURNAL

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function

(2009) M. T. Knuesel et al.   GENES & DEVELOPMENT

Appion: An integrated, database-driven pipeline to facilitate EM image processing

(2009) Gabriel C. Lander et al.   JOURNAL OF STRUCTURAL BIOLOGY

DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy

(2009) N.R. Voss et al.   JOURNAL OF STRUCTURAL BIOLOGY

RNA polymerase II–TFIIB structure and mechanism of transcription initiation

(2009) Dirk Kostrewa et al.   NATURE

Nano positioning system reveals the course of upstream and nontemplate DNA within the RNA polymerase II elongation complex

(2009) Joanna Andrecka et al.   NUCLEIC ACIDS RESEARCH

3D-DART: a DNA structure modelling server

(2009) M. van Dijk et al.   NUCLEIC ACIDS RESEARCH

Structure of an RNA Polymerase II-TFIIB Complex and the Transcription Initiation Mechanism

(2009) X. Liu et al.   SCIENCE

Structure of Eukaryotic RNA Polymerases

(2008) P. Cramer et al.   Annual Review of Biophysics

XPD Helicase Structures and Activities: Insights into the Cancer and Aging Phenotypes from XPD Mutations

(2008) Li Fan et al.   CELL

3DNA: a versatile, integrated software system for the analysis, rebuilding and visualization of three-dimensional nucleic-acid structures

(2008) Xiang-Jun Lu et al.   Nature Protocols