Molecular determinants of mesenchymal cell activation in fibroproliferative diseases

FOXO1/3: Potential suppressors of fibrosis

(2018) Zhenlong Xin et al.   AGEING RESEARCH REVIEWS

TBX4 is involved in the super-enhancer-driven transcriptional programs underlying features specific to lung fibroblasts

(2018) Masafumi Horie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Inhibition of lncRNA PFRL prevents pulmonary fibrosis by disrupting the miR-26a/Smad2 loop

(2018) Hua Jiang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts

(2018) Zhaoping Qin et al.   Cell Communication and Signaling

lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a

(2018) Xuelian Li et al.   FASEB JOURNAL

The lncRNA H19 Mediates Pulmonary Fibrosis by Regulating the miR-196a/COL1A1 Axis

(2018) Qingchun Lu et al.   INFLAMMATION

FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis

(2018) Loka R. Penke et al.   JOURNAL OF CLINICAL INVESTIGATION

Resolution of organ fibrosis

(2018) Joon-Il Jun et al.   JOURNAL OF CLINICAL INVESTIGATION

Methylation of secreted frizzled-related protein 1 (SFRP1) promoter downregulates Wnt/β-catenin activity in keloids

(2018) Jiaqi Liu et al.   JOURNAL OF MOLECULAR HISTOLOGY

Fibroblast growth factor 2 decreases bleomycin-induced pulmonary fibrosis and inhibits fibroblast collagen production and myofibroblast differentiation

(2018) Hyun Young Koo et al.   JOURNAL OF PATHOLOGY

A Rnd3/p190RhoGAP pathway regulates RhoA activity in Idiopathic Pulmonary Fibrosis fibroblasts

(2018) Elizabeth Monaghan-Benson et al.   MOLECULAR BIOLOGY OF THE CELL

lncRNA PFAR Promotes Lung Fibroblast Activation and Fibrosis by Targeting miR-138 to Regulate the YAP1-Twist Axis

(2018) Xiaoguang Zhao et al.   MOLECULAR THERAPY

FoxM1-dependent RAD51 and BRCA2 signaling protects idiopathic pulmonary fibrosis fibroblasts from radiation-induced cell death

(2018) Jintaek Im et al.   Cell Death & Disease

LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d

(2018) Haihai Liang et al.   Theranostics

FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts

(2018) Markaisa Black et al.   Cell Reports

Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis

(2018) Ting Xie et al.   Cell Reports

Runt-Related Transcription Factor 1 (RUNX1) Promotes TGF-β-Induced Renal Tubular Epithelial-to-Mesenchymal Transition (EMT) and Renal Fibrosis through the PI3K Subunit p110δ

(2018) Tong Zhou et al.   EBioMedicine

Yap/Taz mediate mTORC2-stimulated fibroblast activation and kidney fibrosis

(2018) Yuan Gui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiac fibrosis in regenerative medicine: destroy to rebuild

(2018) Gianluca Lorenzo Perrucci et al.   Journal of Thoracic Disease

The Antifibrotic Activity of Prostacyclin Receptor Agonism is Mediated through Inhibition of YAP/TAZ

(2018) Katarina Zmajkovicova et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

MicroRNA-101 attenuates pulmonary fibrosis by inhibiting fibroblast proliferation and activation

(2017) Chaoqun Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins

(2017) Gail Anderson et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Autocrine lysophosphatidic acid signaling activates β-catenin and promotes lung allograft fibrosis

(2017) Pengxiu Cao et al.   JOURNAL OF CLINICAL INVESTIGATION

FGF2-mediated attenuation of myofibroblast activation is modulated by distinct MAPK signaling pathways in human dermal fibroblasts

(2017) David M. Dolivo et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

CD44 is a key player in non-alcoholic steatohepatitis

(2017) Stéphanie Patouraux et al.   JOURNAL OF HEPATOLOGY

KLF 15 Works as an Early Anti-Fibrotic Transcriptional Regulator in Ang II-Induced Renal Fibrosis via Down-Regulation of CTGF Expression

(2017) Xiangchen Gu et al.   KIDNEY & BLOOD PRESSURE RESEARCH

miR-155 regulates high glucose-induced cardiac fibrosis via the TGF-β signaling pathway

(2017) Dong Zhang et al.   Molecular BioSystems

Maresin 1 inhibits transforming growth factor-β1-induced proliferation, migration and differentiation in human lung fibroblasts

(2017) Quanchao Sun et al.   Molecular Medicine Reports

Viral hepatitis and liver cancer

(2017) Marc Ringehan et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

LncRNA GAS5 controls cardiac fibroblast activation and fibrosis by targeting miR-21 via PTEN/MMP-2 signaling pathway

(2017) Hui Tao et al.   TOXICOLOGY

The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways

(2017) Kun Zhang et al.   Nature Communications

MIAT Is a Pro-fibrotic Long Non-coding RNA Governing Cardiac Fibrosis in Post-infarct Myocardium

(2017) Xuefeng Qu et al.   Scientific Reports

mTORC1 activation decreases autophagy in aging and idiopathic pulmonary fibrosis and contributes to apoptosis resistance in IPF fibroblasts

(2016) Yair Romero et al.   AGING CELL

Aging enhances liver fibrotic response in mice through hampering extracellular matrix remodeling

(2016) Bénédicte Delire et al.   Aging-US

Reversal of the Transcriptome by Prostaglandin E2during Myofibroblast Dedifferentiation

(2016) Scott H. Wettlaufer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

MicroRNA-27a-3p Is a Negative Regulator of Lung Fibrosis by Targeting Myofibroblast Differentiation

(2016) Huachun Cui et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Long noncoding RNA H19 controls DUSP5/ERK1/2 axis in cardiac fibroblast proliferation and fibrosis

(2016) Hui Tao et al.   CARDIOVASCULAR PATHOLOGY

Epithelial-mesenchymal transition in tissue repair and fibrosis

(2016) Rivka C. Stone et al.   CELL AND TISSUE RESEARCH

Cardiac fibrosis in myocardial infarction—from repair and remodeling to regeneration

(2016) Virpi Talman et al.   CELL AND TISSUE RESEARCH

MiR-22 may Suppress Fibrogenesis by Targeting TGFβR I in Cardiac Fibroblasts

(2016) Yuan Hong et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

TGF-β signalling and liver disease

(2016) Isabel Fabregat et al.   FEBS Journal

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis

(2016) Ting Xie et al.   JOURNAL OF CLINICAL INVESTIGATION

TGF-β/SMAD Pathway and Its Regulation in Hepatic Fibrosis

(2016) Fengyun Xu et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

Non-Smad Signaling Pathways of the TGF-β Family

(2016) Ying E. Zhang   Cold Spring Harbor Perspectives in Biology

Cellular senescence controls fibrosis in wound healing

(2016) Joon-Il Jun et al.   Aging-US

Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis

(2015) Diptadip Dattaroy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

miR-21 promotes renal fibrosis in diabetic nephropathy by targeting PTEN and SMAD7

(2015) A. D. McClelland et al.   CLINICAL SCIENCE

miR-9-5p suppresses pro-fibrogenic transformation of fibroblasts and prevents organ fibrosis by targeting NOX4 and TGFBR2

(2015) M. Fierro-Fernandez et al.   EMBO REPORTS

Role of Noncoding RNAs as Biomarker and Therapeutic Targets for Liver Fibrosis

(2015) Kun-Yu Teng et al.   GENE EXPRESSION

Long Non-coding RNA Growth Arrest-specific Transcript 5 (GAS5) Inhibits Liver Fibrogenesis through a Mechanism of Competing Endogenous RNA

(2015) Fujun Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Radiation-induced fibrosis: mechanisms and implications for therapy

(2015) Jeffrey M. Straub et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

JAK3/STAT6 Stimulates Bone Marrow-Derived Fibroblast Activation in Renal Fibrosis

(2015) J. Yan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MAPK inhibitors modulate Smad2/3/4 complex cyto-nuclear translocation in myofibroblasts via Imp7/8 mediation

(2015) Yufeng Jiang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Role of human pulmonary fibroblast-derived MCP-1 in cell activation and migration in experimental silicosis

(2015) Xueting Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction

(2015) Juan M. Povedano et al.   Cell Reports

Myofibroblasts in Murine Cutaneous Fibrosis Originate From Adiponectin-Positive Intradermal Progenitors

(2015) Roberta Goncalves Marangoni et al.   Arthritis & Rheumatology

TGF-β/Smad signaling in renal fibrosis

(2015) Xiao-Ming Meng et al.   Frontiers in Physiology

miR-210 promotes IPF fibroblast proliferation in response to hypoxia

(2014) Vidya Bodempudi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

MicroRNA-96 inhibits FoxO3a function in IPF fibroblasts on type I collagen matrix

(2014) Richard Seonghun Nho et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis

(2014) Yong He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Diverse functions of matrix metalloproteinases during fibrosis

(2014) M. Giannandrea et al.   Disease Models & Mechanisms

Diabetes increases pancreatic fibrosis during chronic inflammation

(2014) Dietmar Zechner et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Prostaglandin E2Inhibits α-Smooth Muscle Actin Transcription during Myofibroblast Differentiation via Distinct Mechanisms of Modulation of Serum Response Factor and Myocardin-related Transcription Factor-A

(2014) Loka R. K. Penke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Secreted fibroblast-derived miR-34a induces tubular cell apoptosis in fibrotic kidney

(2014) Yang Zhou et al.   JOURNAL OF CELL SCIENCE

The Antifibrotic Effects and Mechanisms of MicroRNA-26a Action in Idiopathic Pulmonary Fibrosis

(2014) Haihai Liang et al.   MOLECULAR THERAPY

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mucin 5B Promoter Polymorphism Is Associated with Susceptibility to Interstitial Lung Diseases in Chinese Males

(2014) Chunli Wang et al.   PLoS One

RUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation

(2014) Woosook Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibroblasts in fibrosis: novel roles and mediators

(2014) Ryan T. Kendall et al.   Frontiers in Pharmacology

Heterogeneity in fibroblast proliferation and survival in idiopathic pulmonary fibrosis

(2014) David M. Habiel et al.   Frontiers in Pharmacology

A case of pulmonary fibrosis associated with rheumatoid arthritis, scleroderma sine scleroderma and ANCA associated vasculitis

(2014) Amritpal Anand et al.   SpringerPlus

Fibrosis and renal aging

(2014) Hai-Chun Yang et al.   Kidney International Supplements

Role of Lung Pericytes and Resident Fibroblasts in the Pathogenesis of Pulmonary Fibrosis

(2013) Chi Hung et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Reversal of Myofibroblast Differentiation by Prostaglandin E2

(2013) Garth Garrison et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

X-Linked Inhibitor of Apoptosis Regulates Lung Fibroblast Resistance to Fas-Mediated Apoptosis

(2013) Iyabode O. Ajayi et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis

(2013) Clara Dees et al.   ANNALS OF THE RHEUMATIC DISEASES

Connective tissue growth factor induces collagen I expression in human lung fibroblasts through the Rac1/MLK3/JNK/AP-1 pathway

(2013) Chien-Huang Lin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Anoikis molecular pathways and its role in cancer progression

(2013) Paolo Paoli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mechanistic links between aging and lung fibrosis

(2013) Victor J. Thannickal   BIOGERONTOLOGY

Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition

(2013) David Balli et al.   EMBO JOURNAL

miR-145 regulates myofibroblast differentiation and lung fibrosis

(2013) Shanzhong Yang et al.   FASEB JOURNAL

Transforming Growth Factor-β1 (TGF-β1)-stimulated Fibroblast to Myofibroblast Differentiation Is Mediated by Hyaluronan (HA)-facilitated Epidermal Growth Factor Receptor (EGFR) and CD44 Co-localization in Lipid Rafts

(2013) Adam C. Midgley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiotensin II stimulates cardiac fibroblast migration via the differential regulation of matrixins and RECK

(2013) Jalahalli M. Siddesha et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

FoxO3a (Forkhead Box O3a) Deficiency Protects Idiopathic Pulmonary Fibrosis (IPF) Fibroblasts from Type I Polymerized Collagen Matrix-Induced Apoptosis via Caveolin-1 (cav-1) and Fas

(2013) Richard Seonghun Nho et al.   PLoS One

Mucin 5B promoter polymorphism is associated with idiopathic pulmonary fibrosis but not with development of lung fibrosis in systemic sclerosis or sarcoidosis

(2013) Carmel J Stock et al.   THORAX

Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts

(2013) S K Huang et al.   Cell Death & Disease

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

(2013) Ingmar Mederacke et al.   Nature Communications

miR-199a-5p Is Upregulated during Fibrogenic Response to Tissue Injury and Mediates TGFbeta-Induced Lung Fibroblast Activation by Targeting Caveolin-1

(2013) Christian Lacks Lino Cardenas et al.   PLoS Genetics

Profibrotic Role of miR-154 in Pulmonary Fibrosis

(2012) Jadranka Milosevic et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Host Responses in Tissue Repair and Fibrosis

(2012) Jeremy S. Duffield et al.   Annual Review of Pathology-Mechanisms of Disease

Fasudil, a Rho-Kinase Inhibitor, Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice

(2012) Chunguo Jiang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Decreased expression of autophagic beclin 1 protein in idiopathic pulmonary fibrosis fibroblasts

(2012) Alberto Ricci et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Unknown

(2012) Wang Ju et al.   MOLECULAR MEDICINE

Rapamycin Ameliorates Kidney Fibrosis by Inhibiting the Activation of mTOR Signaling in Interstitial Macrophages and Myofibroblasts

(2012) Guochun Chen et al.   PLoS One

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

(2012) T. Kisseleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resident Tissue-Specific Mesenchymal Progenitor Cells Contribute to Fibrogenesis in Human Lung Allografts

(2011) Natalie Walker et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of Endothelial-Mesenchymal Transition (EndoMT) in the Pathogenesis of Fibrotic Disorders

(2011) Sonsoles Piera-Velazquez et al.   AMERICAN JOURNAL OF PATHOLOGY

Participation of miR-200 in Pulmonary Fibrosis

(2011) Shanzhong Yang et al.   AMERICAN JOURNAL OF PATHOLOGY

Prostaglandin E2As an Inhibitory Modulator of Fibrogenesis in Human Lung Allografts

(2011) Natalie M. Walker et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Akt, FoxO and regulation of apoptosis

(2011) Xinbo Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Non-coding RNAs as regulators of gene expression and epigenetics

(2011) M. U. Kaikkonen et al.   CARDIOVASCULAR RESEARCH

Reversible differentiation of myofibroblasts by MyoD

(2011) Louise Hecker et al.   EXPERIMENTAL CELL RESEARCH

The rno-miR-34 family is upregulated and targets ACSL1 in dimethylnitrosamine-induced hepatic fibrosis in rats

(2011) Wei-Qing Li et al.   FEBS Journal

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

(2011) Bin Gao et al.   GASTROENTEROLOGY

TGF-β signaling in fibrosis

(2011) Anna Biernacka et al.   GROWTH FACTORS

Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis

(2011) Jeffrey C. Horowitz et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Human Hyaluronan Synthase 2 (HAS2) Gene and Its Natural Antisense RNA Exhibit Coordinated Expression in the Renal Proximal Tubular Epithelial Cell

(2011) Daryn R. Michael et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44

(2011) Yuejuan Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Wnt3a Induces Myofibroblast Differentiation by Upregulating TGF-β Signaling Through SMAD2 in a β-Catenin-Dependent Manner

(2011) Jon M. Carthy et al.   PLoS One

Activation of WNT / β-Catenin Signaling in Pulmonary Fibroblasts by TGF-β1 Is Increased in Chronic Obstructive Pulmonary Disease

(2011) Hoeke A. Baarsma et al.   PLoS One

Inhibition of PI3K Prevents the Proliferation and Differentiation of Human Lung Fibroblasts into Myofibroblasts: The Role of Class I P110 Isoforms

(2011) Enrico Conte et al.   PLoS One

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

(2011) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic Regulation of Myofibroblast Differentiation by DNA Methylation

(2010) Biao Hu et al.   AMERICAN JOURNAL OF PATHOLOGY

Hypermethylation of PTGER2 Confers Prostaglandin E2 Resistance in Fibrotic Fibroblasts from Humans and Mice

(2010) Steven K. Huang et al.   AMERICAN JOURNAL OF PATHOLOGY

miR-29 Is a Major Regulator of Genes Associated with Pulmonary Fibrosis

(2010) Leah Cushing et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Integrin–TGF-β crosstalk in fibrosis, cancer and wound healing

(2010) Coert Margadant et al.   EMBO REPORTS

Enhanced MCP-1 release by keloid CD14+ cells augments fibroblast proliferation: role of MCP-1 and Akt pathway in keloids

(2010) Wei-Ting Liao et al.   EXPERIMENTAL DERMATOLOGY

Genetic Labeling Does Not Detect Epithelial-to-Mesenchymal Transition of Cholangiocytes in Liver Fibrosis in Mice

(2010) David Scholten et al.   GASTROENTEROLOGY

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

(2010) Fei Liu et al.   JOURNAL OF CELL BIOLOGY

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis

(2010) Eleonora Patsenker et al.   JOURNAL OF HEPATOLOGY

Transforming growth factor (TGF)-β signaling in cardiac remodeling

(2010) Marcin Dobaczewski et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

(2010) Joon-Il Jun et al.   NATURE CELL BIOLOGY

Methylation determines fibroblast activation and fibrogenesis in the kidney

(2010) Wibke Bechtel et al.   NATURE MEDICINE

PPARγ Downregulation by TGFß in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis

(2010) Jun Wei et al.   PLoS One

Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice

(2010) Sergey Udalov et al.   BMC Pulmonary Medicine

Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

(2009) Benjamin D. Humphreys et al.   AMERICAN JOURNAL OF PATHOLOGY

Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation

(2009) Senthil K. Venugopal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Targeted Injury of Type II Alveolar Epithelial Cells Induces Pulmonary Fibrosis

(2009) Thomas H. Sisson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

WNT5A Is a Regulator of Fibroblast Proliferation and Resistance to Apoptosis

(2009) Louis J. Vuga et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Osteopontin Induces Airway Remodeling and Lung Fibroblast Activation in a Murine Model of Asthma

(2009) Martin Kohan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Critical Role of Serum Response Factor in Pulmonary Myofibroblast Differentiation Induced by TGF-β

(2009) Nathan Sandbo et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mechanisms of transforming growth factor β1/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts

(2009) S. He et al.   BRITISH JOURNAL OF DERMATOLOGY

Peroxisome proliferator-activated receptor-γ abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator

(2009) Asish K. Ghosh et al.   FASEB JOURNAL

Prostaglandin E2 induces fibroblast apoptosis by modulating multiple survival pathways

(2009) Steven K. Huang et al.   FASEB JOURNAL

MeCP2 Controls an Epigenetic Pathway That Promotes Myofibroblast Transdifferentiation and Fibrosis

(2009) Jelena Mann et al.   GASTROENTEROLOGY

Phosphatase and Tensin Homologue on Chromosome 10 (PTEN) Directs Prostaglandin E2-mediated Fibroblast Responses via Regulation of E Prostanoid 2 Receptor Expression

(2009) Rommel L. Sagana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defective Histone Acetylation Is Responsible for the Diminished Expression of Cyclooxygenase 2 in Idiopathic Pulmonary Fibrosis

(2009) W. R. Coward et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of Keratinocyte Growth Factor as a Target of microRNA-155 in Lung Fibroblasts: Implication in Epithelial-Mesenchymal Interactions

(2009) Nicolas Pottier et al.   PLoS One

Fibroblasts and myofibroblasts in wound healing: Force generation and measurement

(2009) Bin Li et al.   Journal of Tissue Viability

Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney

(2008) Shuei-Liong Lin et al.   AMERICAN JOURNAL OF PATHOLOGY

Prostaglandin E2Inhibits Specific Lung Fibroblast Functions via Selective Actions of PKA and Epac-1

(2008) Steven K. Huang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts

(2008) Alfiya Akhmetshina et al.   ARTHRITIS AND RHEUMATISM

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis

(2008) Hong Xia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hic-5 Promotes the Hypertrophic Scar Myofibroblast Phenotype by Regulating the TGF-β1 Autocrine Loop

(2008) Ganary Dabiri et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Kruppel-like factor KLF15 inhibits connective tissue growth factor (CTGF) expression in cardiac fibroblasts

(2008) Baiqiu Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis

(2008) Melanie Königshoff et al.   PLoS One

Integration of non-SMAD and SMAD signaling in TGF-β1-induced plasminogen activator inhibitor type-1 gene expression in vascular smooth muscle cells

(2008) Rohan Samarakoon et al.   THROMBOSIS AND HAEMOSTASIS

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY