Critical assessment and integration of separate lines of evidence for risk assessment of chemical mixtures

Statistical Methodology in Studies of Prenatal Exposure to Mixtures of Endocrine-Disrupting Chemicals: A Review of Existing Approaches and New Alternatives

(2019) Nina Lazarevic et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Indicator PCBs in farmed and wild fish in Greece - Risk assessment for the Greek population

(2019) Elisavet A. Renieri et al.   FOOD AND CHEMICAL TOXICOLOGY

Cumulative risk assessment of pesticide residues in different Iranian pistachio cultivars: Applying the source specific HQS and adversity specific HIA approaches in Real Life Risk Simulations (RLRS)

(2019) Seyedeh Faezeh Taghizadeh et al.   TOXICOLOGY LETTERS

Adverse and hormetic effects in rats exposed for 12 months to low dose mixture of 13 chemicals: RLRS part III

(2019) Anca Oana Docea et al.   TOXICOLOGY LETTERS

Adverse outcome pathway networks I: Development and applications

(2018) Dries Knapen et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Six months exposure to a real life mixture of 13 chemicals' below individual NOAELs induced non monotonic sex-dependent biochemical and redox status changes in rats

(2018) Anca Oana Docea et al.   FOOD AND CHEMICAL TOXICOLOGY

Tox21 Enricher: Web-based Chemical/Biological Functional Annotation Analysis Tool Based on Tox21 Toxicity Screening Platform

(2018) Junguk Hur et al.   Molecular Informatics

Current EU research activities on combined exposure to multiple chemicals

(2018) Stephanie K. Bopp et al.   ENVIRONMENT INTERNATIONAL

Simulating exposure-related behaviors using agent-based models embedded with needs-based artificial intelligence

(2018) Namdi Brandon et al.   Journal of Exposure Science and Environmental Epidemiology

Toxicology for Real-Life Risk Simulation - Editorial Preface to this Special Issue

(2018) Aristidis Tsatsakis et al.   TOXICOLOGY LETTERS

Hormetic Neurobehavioral effects of low dose toxic chemical mixtures in real-life risk simulation (RLRS) in rats

(2018) Aristidis M. Tsatsakis et al.   FOOD AND CHEMICAL TOXICOLOGY

Quantitative Adverse Outcome Pathways and Their Application to Predictive Toxicology

(2017) Rory B. Conolly et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Modeling of adipose/blood partition coefficient for environmental chemicals

(2017) K.C. Papadaki et al.   FOOD AND CHEMICAL TOXICOLOGY

Development of QSARs for parameterizing Physiology Based ToxicoKinetic models

(2017) Dimosthenis Α. Sarigiannis et al.   FOOD AND CHEMICAL TOXICOLOGY

Human exposure to chemical mixtures: Challenges for the integration of toxicology with epidemiology data in risk assessment

(2017) Antonio F. Hernández et al.   FOOD AND CHEMICAL TOXICOLOGY

Divergent responsiveness of two isoforms of the estrogen receptor to mixtures of contaminants of emerging concern in four vertebrates

(2017) Satomi Kohno et al.   JOURNAL OF APPLIED TOXICOLOGY

Omics-Based Platform for Studying Chemical Toxicity Using Stem Cells

(2017) Yan Han et al.   JOURNAL OF PROTEOME RESEARCH

Dynamically tunable cell culture platforms for tissue engineering and mechanobiology

(2017) Koichiro Uto et al.   PROGRESS IN POLYMER SCIENCE

The challenge of the application of 'omics technologies in chemicals risk assessment: Background and outlook

(2017) Ursula G. Sauer et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Relevance and reliability of experimental data in human health risk assessment of pesticides

(2017) Johanna Kaltenhäuser et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Effects of engineered nanoparticles on the innate immune system

(2017) Yuanchang Liu et al.   SEMINARS IN IMMUNOLOGY

The Role of Omics in the Application of Adverse Outcome Pathways for Chemical Risk Assessment

(2017) Erica K. Brockmeier et al.   TOXICOLOGICAL SCIENCES

Interactions between cadmium and decabrominated diphenyl ether on blood cells count in rats—Multiple factorial regression analysis

(2017) Marijana Curcic et al.   TOXICOLOGY

21st Century Cell Culture for 21st Century Toxicology

(2016) David Pamies et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A critical review of frameworks used for evaluating reliability and relevance of (eco)toxicity data: Perspectives for an integrated eco-human decision-making framework

(2016) N. Roth et al.   ENVIRONMENT INTERNATIONAL

Biomonitoring in the Era of the Exposome

(2016) Kristine K. Dennis et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

What Can Epidemiological Studies Tell Us about the Impact of Chemical Mixtures on Human Health?

(2016) Joseph M. Braun et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Statistical Approaches for Assessing Health Effects of Environmental Chemical Mixtures in Epidemiology: Lessons from an Innovative Workshop

(2016) Kyla W. Taylor et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Integrated exposure and risk characterization of bisphenol-A in Europe

(2016) Dimosthenis A. Sarigiannis et al.   FOOD AND CHEMICAL TOXICOLOGY

New challenges in risk assessment of chemicals when simulating real exposure scenarios; simultaneous multi-chemicals' low dose exposure

(2016) Aristidis M. Tsatsakis et al.   FOOD AND CHEMICAL TOXICOLOGY

Simulating real-life exposures to uncover possible risks to human health: A proposed consensus for a novel methodological approach

(2016) AM Tsatsakis et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Regulatory assessment of chemical mixtures: Requirements, current approaches and future perspectives

(2016) Aude Kienzler et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Assessment of synergistic thyroid disrupting effects of a mixture of EDCs in ovariectomized rats using factorial analysis and dose addition

(2016) Hao Chen et al.   Toxicology Research

Contribution of new technologies to characterization and prediction of adverse effects

(2015) David Rouquié et al.   CRITICAL REVIEWS IN TOXICOLOGY

Passive exposures of children to volatile trihalomethanes during domestic cleaning activities of their parents

(2015) Syam S. Andra et al.   ENVIRONMENTAL RESEARCH

Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model

(2015) Patience Browne et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Impact of co-exposure with lead and decabromodiphenyl ether (BDE-209) on thyroid function in zebrafish larvae

(2014) Biran Zhu et al.   AQUATIC TOXICOLOGY

Biomonitoring of dialkylphosphate metabolites (DAPs) in urine and hair samples of sprayers and rural residents of Crete, Greece

(2014) Aikaterini Kokkinaki et al.   ENVIRONMENTAL RESEARCH

Cadmium and decabrominated diphenyl ether mixture: In vitro evaluation of cytotoxic, prooxidative and genotoxic effects

(2014) Marijana Curcic et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Biological and medical applications of a brain-on-a-chip

(2014) David Pamies et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Organs-on-a-chip: a new tool for drug discovery

(2014) Alessandro Polini et al.   Expert Opinion on Drug Discovery

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA)

(2014) Knut Erik Tollefsen et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Environmental contaminants and target organ toxicities – new insights into old problems

(2014) Martin F. Wilks et al.   TOXICOLOGY LETTERS

Which chemicals drive biological effects in wastewater and recycled water?

(2014) Janet Y.M. Tang et al.   WATER RESEARCH

Combined effects of cadmium and decabrominated diphenyl ether on thyroid hormones in rats

(2013) Marijana Ćurčić et al.   Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology

Statistical strategies for constructing health risk models with multiple pollutants and their interactions: possible choices and comparisons

(2013) Zhichao Sun et al.   Environmental Health

Effects-directed analysis (EDA) and toxicity identification evaluation (TIE): Complementary but different approaches for diagnosing causes of environmental toxicity

(2013) Robert M. Burgess et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Environmental risk assessment of combined effects in aquatic ecotoxicology: A discussion paper

(2013) Jonny Beyer et al.   MARINE ENVIRONMENTAL RESEARCH

The impact of prolonged cadmium exposure and co-exposure with polychlorinated biphenyls on thyroid function in rats

(2013) Aleksandra Buha et al.   TOXICOLOGY LETTERS

Considering the cumulative risk of mixtures of chemicals – A challenge for policy makers

(2012) Denis A Sarigiannis et al.   Environmental Health

International experience in addressing combined exposures: Increasing the efficiency of assessment

(2012) M.E. (Bette) Meek   TOXICOLOGY

Toxic effects of pesticide mixtures at a molecular level: Their relevance to human health

(2012) Antonio F. Hernández et al.   TOXICOLOGY

Frequent item set mining

(2012) Christian Borgelt   Wiley Interdisciplinary Reviews-Data Mining and Knowledge Discovery

Critical analysis of literature on low-dose synergy for use in screening chemical mixtures for risk assessment

(2011) Alan Boobis et al.   CRITICAL REVIEWS IN TOXICOLOGY

Microfluidic cell culture models for tissue engineering

(2011) Niraj K Inamdar et al.   CURRENT OPINION IN BIOTECHNOLOGY

Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors

(2011) Ruili Huang et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Statistical, Epidemiological, and Risk-Assessment Approaches to Evaluating Safety of Vaccines Throughout the Life Cycle at the Food and Drug Administration

(2011) R. Ball et al.   PEDIATRICS

Systematic review of biomonitoring studies to determine the association between exposure to organophosphorus and pyrethroid insecticides and human health outcomes

(2011) Michalis Koureas et al.   TOXICOLOGY LETTERS

Perinatal Exposure to Bisphenol A: The Route of Administration Makes the Dose

(2010) Denis Sarigiannis et al.   EPIDEMIOLOGY

A stochastic whole-body physiologically based pharmacokinetic model to assess the impact of inter-individual variability on tissue dosimetry over the human lifespan

(2010) Rémy Beaudouin et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Evaluation of the impact of the exposure route on the human kinetic adjustment factor

(2010) M. Valcke et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Spatially explicit multimedia fate models for pollutants in Europe: State of the art and perspectives

(2010) A. Pistocchi et al.   SCIENCE OF THE TOTAL ENVIRONMENT

A generalized physiologically-based toxicokinetic modeling system for chemical mixtures containing metals

(2010) Alan F Sasso et al.   Theoretical Biology and Medical Modelling

PBPK modelling of inter-individual variability in the pharmacokinetics of environmental chemicals

(2010) Frédéric Y. Bois et al.   TOXICOLOGY

A Bayesian population PBPK model for multiroute chloroform exposure

(2009) Yuching Yang et al.   Journal of Exposure Science and Environmental Epidemiology

Probabilistic Exposure Analysis for Chemical Risk Characterization

(2009) Kenneth T. Bogen et al.   TOXICOLOGICAL SCIENCES

Physiologically Based Pharmacokinetic Modeling of Persistent OrganicPollutants for Lifetime Exposure Assessment: A New Tool in Breast CancerEpidemiologic Studies

(2008) Marc-André Verner et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Predicting Plasma Concentrations of Bisphenol A in Children Younger Than 2 Years of Age after Typical Feeding Schedules, using a Physiologically Based Toxicokinetic Model

(2008) Andrea N. Edginton et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Environmental epidemiology and risk assessment

(2008) Bert Brunekreef   TOXICOLOGY LETTERS