Single Cell Imaging of Nuclear Architecture Changes

Sun-mediated mechanical LINC between nucleus and cytoskeleton regulates βcatenin nuclear access

(2018) Gunes Uzer et al.   JOURNAL OF BIOMECHANICS

Emerging views of the nucleus as a cellular mechanosensor

(2018) Tyler J. Kirby et al.   NATURE CELL BIOLOGY

Molecular mechanisms driving transcriptional stress responses

(2018) Anniina Vihervaara et al.   NATURE REVIEWS GENETICS

Noninvasive detection of macrophage activation with single-cell resolution through machine learning

(2018) Nicolas Pavillon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenomic Modifications Mediating Antibody Maturation

(2018) Emily C. Sheppard et al.   Frontiers in Immunology

Chromatin Dynamics in Genome Stability: Roles in Suppressing Endogenous DNA Damage and Facilitating DNA Repair

(2017) Nidhi Nair et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanosensing by the nucleus: From pathways to scaling relationships

(2017) Sangkyun Cho et al.   JOURNAL OF CELL BIOLOGY

Emerging roles of mechanical forces in chromatin regulation

(2017) Yekaterina A. Miroshnikova et al.   JOURNAL OF CELL SCIENCE

A microfluidic device for characterizing nuclear deformations

(2017) Andrew C. Hodgson et al.   LAB ON A CHIP

Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation

(2017) Kyong-Rim Kieffer-Kwon et al.   MOLECULAR CELL

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response

(2017) Andrew N. Blackford et al.   MOLECULAR CELL

Enhanced spectral histology in the colon using high-magnification benchtop FTIR imaging

(2017) Jayakrupakar Nallala et al.   VIBRATIONAL SPECTROSCOPY

Raman spectroscopy as a tool for label-free lymphocyte cell line discrimination

(2016) Alison J. Hobro et al.   ANALYST

The importance of hydration and DNA conformation in interpreting infrared spectra of cells and tissues

(2016) Bayden R. Wood   CHEMICAL SOCIETY REVIEWS

High resolution FTIR imaging provides automated discrimination and detection of single malaria parasite infected erythrocytes on glass

(2016) David Perez-Guaita et al.   FARADAY DISCUSSIONS

Transcription upregulation via force-induced direct stretching of chromatin

(2016) Arash Tajik et al.   NATURE MATERIALS

Using Raman spectroscopy to characterize biological materials

(2016) Holly J Butler et al.   Nature Protocols

Spatial organization of chromatin domains and compartments in single chromosomes

(2016) Siyuan Wang et al.   SCIENCE

Targeting DNA Repair in Cancer: Beyond PARP Inhibitors

(2016) Jessica S. Brown et al.   Cancer Discovery

High resolution FTIR imaging provides automated discrimination and detection of single malaria parasite infected erythrocytes on glass

(2016) David Perez-Guaita et al.   FARADAY DISCUSSIONS

An RNA-aptamer-based two-color CRISPR labeling system

(2016) Siyuan Wang et al.   Scientific Reports

The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity

(2016) Samer G. Alam et al.   Scientific Reports

Global gene regulation during activation of immunoglobulin class switching in human B cells

(2016) Youming Zhang et al.   Scientific Reports

Non-label immune cell state prediction using Raman spectroscopy

(2016) Taro Ichimura et al.   Scientific Reports

Ex vivo engineered immune organoids for controlled germinal center reactions

(2015) Alberto Purwada et al.   BIOMATERIALS

The nucleus is an intracellular propagator of tensile forces in NIH 3T3 fibroblasts

(2015) S. G. Alam et al.   JOURNAL OF CELL SCIENCE

Real-time deformability cytometry: on-the-fly cell mechanical phenotyping

(2015) Oliver Otto et al.   NATURE METHODS

Histone exchange, chromatin structure and the regulation of transcription

(2015) Swaminathan Venkatesh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CASFISH: CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells

(2015) Wulan Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the metazoan Nup62bulletNup58bulletNup54 nucleoporin complex

(2015) H. Chug et al.   SCIENCE

Architecture of the fungal nuclear pore inner ring complex

(2015) T. Stuwe et al.   SCIENCE

Divergence of transcriptional landscape occurs early in B cell activation

(2015) Trent Fowler et al.   Epigenetics & Chromatin

The activation of IgM- or isotype-switched IgG- and IgE-BCR exhibits distinct mechanical force sensitivity and threshold

(2015) Zhengpeng Wan et al.   eLife

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

Cellular microenvironments reveal defective mechanosensing responses and elevated YAP signaling in LMNA-mutated muscle precursors

(2014) A. T. Bertrand et al.   JOURNAL OF CELL SCIENCE

Auxetic nuclei in embryonic stem cells exiting pluripotency

(2014) Stefano Pagliara et al.   NATURE MATERIALS

Using Fourier transform IR spectroscopy to analyze biological materials

(2014) Matthew J Baker et al.   Nature Protocols

Appreciating force and shape — the rise of mechanotransduction in cell biology

(2014) Thomas Iskratsch et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cellular mechanosensing: Getting to the nucleus of it all

(2014) Gregory R. Fedorchak et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Nuclear Envelope Lamin-A Couples Actin Dynamics with Immunological Synapse Architecture and T Cell Activation

(2014) J. M. Gonzalez-Granado et al.   Science Signaling

LINC complexes in health and disease

(2014) Alexandre Méjat   Nucleus

scikit-image: image processing in Python

(2014) Stéfan van der Walt et al.   PeerJ

Global Regulation of Promoter Melting in Naive Lymphocytes

(2013) Fedor Kouzine et al.   CELL

Single-cell Hi-C reveals cell-to-cell variability in chromosome structure

(2013) Takashi Nagano et al.   NATURE

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Contrasting Quiescent G0 Phase with Mitotic Cell Cycling in the Mouse Immune System

(2013) Michio Tomura et al.   PLoS One

Ring cycle for dilating and constricting the nuclear pore

(2013) S. R. Solmaz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of B Cell Immunity

(2013) David Parra et al.   Annual Review of Animal Biosciences

MAP kinase signalling cascades and transcriptional regulation

(2012) Shen-Hsi Yang et al.   GENE

Vibrational spectroscopic changes of B-lymphocytes upon activation

(2012) Antonella I. Mazur et al.   Journal of Biophotonics

Hydrodynamic stretching of single cells for large population mechanical phenotyping

(2012) D. R. Gossett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combinatorial mechanisms regulating AID-dependent DNA deamination: Interacting proteins and post-translational modifications

(2012) Bao Q. Vuong et al.   SEMINARS IN IMMUNOLOGY

Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells

(2011) Piyush B. Gupta et al.   CELL

Monitoring the reversible B to A-like transition of DNA in eukaryotic cells using Fourier transform infrared spectroscopy

(2011) Donna R. Whelan et al.   NUCLEIC ACIDS RESEARCH

Systematic Protein Location Mapping Reveals Five Principal Chromatin Types in Drosophila Cells

(2010) Guillaume J. Filion et al.   CELL

Chromatin condensation via the condensin II complex is required for peripheral T-cell quiescence

(2010) Jason S Rawlings et al.   EMBO JOURNAL

Epigenetic regulation of V(D)J recombination

(2010) Kristen Johnson et al.   Essays in Biochemistry

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Attenuated hypertrophic response to pressure overload in a lamin A/C haploinsufficiency mouse

(2009) Mihaela Cupesi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The nuclear envelope as an integrator of nuclear and cytoplasmic architecture

(2008) Melissa Crisp et al.   FEBS LETTERS

Comparative Proteomic Phenotyping of Cell Lines and Primary Cells to Assess Preservation of Cell Type-specific Functions

(2008) Cuiping Pan et al.   MOLECULAR & CELLULAR PROTEOMICS

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY