Overexpression of Sirtuin 6 suppresses cellular senescence and NF-κB mediated inflammatory responses in osteoarthritis development

Sirtuin 6 nuclear localization at cortical brain level of young diabetic mice: An immunohistochemical study

(2013) Gaia Favero et al.   ACTA HISTOCHEMICA

Overexpression of Sirtuin 6 Suppresses Inflammatory Responses and Bone Destruction in Mice With Collagen-Induced Arthritis

(2013) Hwa-Suk Lee et al.   ARTHRITIS AND RHEUMATISM

Sirt2 suppresses inflammatory responses in collagen-induced arthritis

(2013) Jiangtao Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Role of SIRT6 Protein in Aging and Reprogramming of Human Induced Pluripotent Stem Cells

(2013) Amit Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The sirtuin SIRT6 regulates stress granule formation in C. elegans and mammals

(2013) M. Jedrusik-Bode et al.   JOURNAL OF CELL SCIENCE

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling

(2013) Jinying Piao et al.   Scientific Reports

The role of synovitis in osteoarthritis pathogenesis

(2012) Carla R. Scanzello et al.   BONE

SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence

(2012) Anna Cardus et al.   CARDIOVASCULAR RESEARCH

Role of Interleukin-1 Inhibitors in Osteoarthritis

(2012) Zdravko Jotanovic et al.   DRUGS & AGING

SIRT3 gene expression: A link between inherited mitochondrial DNA variants and oxidative stress

(2012) Patrizia D'Aquila et al.   GENE

Cytoprotective and anti-inflammatory effects of melatonin in hydrogen peroxide-stimulated CHON-001 human chondrocyte cell line and rabbit model of osteoarthritis via the SIRT1 pathway

(2012) Hyun-Dae Lim et al.   JOURNAL OF PINEAL RESEARCH

SIRT3 Weighs Heavily in the Metabolic Balance: A New Role for SIRT3 in Metabolic Syndrome

(2012) M. F. Green et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The sirtuin SIRT6 regulates lifespan in male mice

(2012) Yariv Kanfi et al.   NATURE

Are sirtuins viable targets for improving healthspan and lifespan?

(2012) Joseph A. Baur et al.   NATURE REVIEWS DRUG DISCOVERY

Sirtuins mediate mammalian metabolic responses to nutrient availability

(2012) Angeliki Chalkiadaki et al.   Nature Reviews Endocrinology

Sub-cellular localization, expression and functions of Sirt6 during the cell cycle in HeLa cells

(2012) Pooneh Memar Ardestani et al.   Nucleus

Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis

(2012) Mary B. Goldring   Therapeutic Advances in Musculoskeletal Disease

Increased interleukin-1β gene expression in peripheral blood leukocytes is associated with increased pain and predicts risk for progression of symptomatic knee osteoarthritis

(2011) Mukundan Attur et al.   ARTHRITIS AND RHEUMATISM

SOX Trio Decrease in the Articular Cartilage with the Advancement of Osteoarthritis

(2011) Jai-Sun Lee et al.   CONNECTIVE TISSUE RESEARCH

Structure and Biochemical Functions of SIRT6

(2011) Patricia W. Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells

(2010) Shunsuke Minagawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

NF-κB Signaling: Multiple Angles to Target OA

(2010) Kenneth B. Marcu et al.   CURRENT DRUG TARGETS

Potential involvement of SIRT1 in the pathogenesis of osteoarthritis through the modulation of chondrocyte gene expressions

(2010) Norifumi Fujita et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Functional dissection of SIRT6: Identification of domains that regulate histone deacetylase activity and chromatin localization

(2010) Ruth I. Tennen et al.   MECHANISMS OF AGEING AND DEVELOPMENT

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

(2009) Tiara L.A. Kawahara et al.   CELL

NF-κB Signaling in the Aging Process

(2009) Antero Salminen et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Quantification of cytokines and inflammatory mediators in a three-dimensional model of inflammatory arthritis

(2008) Muhammad F. Rai et al.   CYTOKINE