­­­­­Insulin-Like Growth Factor II (IGF-II) Inhibits IL-1β-Induced Cartilage Matrix Loss and Promotes Cartilage Integrity in Experimental Osteoarthritis

Loss of Frzb and Sfrp1 differentially affects joint homeostasis in instability-induced osteoarthritis

(2015) S. Thysen et al.   OSTEOARTHRITIS AND CARTILAGE

Analysis of the Trajectory of Osteoarthritis Development in a Mouse Model by Serial Near-Infrared Fluorescence Imaging of Matrix Metalloproteinase Activities

(2015) Averi A. Leahy et al.   Arthritis & Rheumatology

Regulation of the Catabolic Cascade in Osteoarthritis by the Zinc-ZIP8-MTF1 Axis

(2014) Jin-Hong Kim et al.   CELL

Mouse synovial mesenchymal stem cells increase in yield with knee inflammation

(2014) Yu Matsukura et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis

(2014) Bridgette D Furman et al.   ARTHRITIS RESEARCH & THERAPY

Identification of α2-Macroglobulin as a Master Inhibitor of Cartilage-Degrading Factors That Attenuates the Progression of Posttraumatic Osteoarthritis

(2014) Shaowei Wang et al.   Arthritis & Rheumatology

Tumors, IGF-2, and Hypoglycemia: Insights From the Clinic, the Laboratory, and the Historical Archive

(2013) Yevgeniya Dynkevich et al.   ENDOCRINE REVIEWS

Membrane Chaperone SecDF Plays a Role in the Secretion of Listeria monocytogenes Major Virulence Factors

(2013) T. Burg-Golani et al.   JOURNAL OF BACTERIOLOGY

The Phospholipase C Inhibitor U73122 Attenuates trans-10, cis-12 Conjugated Linoleic Acid-Mediated Inflammatory Signaling and Insulin Resistance in Human Adipocytes

(2013) Wan Shen et al.   JOURNAL OF NUTRITION

Proteoglycan 4 Expression Protects Against the Development of Osteoarthritis

(2013) M. Z. C. Ruan et al.   Science Translational Medicine

Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice

(2012) Hwanhee Oh et al.   ARTHRITIS AND RHEUMATISM

Osteoarthritis: A disease of the joint as an organ

(2012) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo

(2012) Annika Burleigh et al.   ARTHRITIS AND RHEUMATISM

Role of Interleukin-1 Inhibitors in Osteoarthritis

(2012) Zdravko Jotanovic et al.   DRUGS & AGING

Species-specific biological effects of FGF-2 in articular cartilage: Implication for distinct roles within the FGF receptor family

(2012) Xin Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Regulation of H19 and its encoded microRNA-675 in osteoarthritis and under anabolic and catabolic in vitro conditions

(2012) Eric Steck et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis

(2012) Mary B. Goldring   Therapeutic Advances in Musculoskeletal Disease

GSK-3β/CREB axis mediates IGF-1-induced ECM/adhesion molecule expression, cell cycle progression and monolayer permeability in retinal capillary endothelial cells: Implications for diabetic retinopathy

(2011) Takhellambam S. Devi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Signalling by insulin and IGF receptors: supporting acts and new players

(2011) Kenneth Siddle   JOURNAL OF MOLECULAR ENDOCRINOLOGY

IGF-1 and PDGF-bb Suppress IL-1β-Induced Cartilage Degradation through Down-Regulation of NF-κB Signaling: Involvement of Src/PI-3K/AKT Pathway

(2011) Azadeh Montaseri et al.   PLoS One

Segregation of myoblast fusion and muscle-specific gene expression by distinct ligand-dependent inactivation of GSK-3β

(2010) N. A. M. Pansters et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

NF-κB Signaling: Multiple Angles to Target OA

(2010) Kenneth B. Marcu et al.   CURRENT DRUG TARGETS

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

A comparison of the involvement of p38, ERK1/2 and PI3K in growth factor-induced chondrogenic differentiation of mesenchymal stem cells

(2008) Louise A. McMahon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endothelial progenitor cell homing: prominent role of the IGF2-IGF2R-PLC 2 axis

(2008) Y.-S. Maeng et al.   BLOOD

IGF2-driven PI3 kinase and TGFβ signaling pathways in chondrogenesis

(2008) K HAMAMURA et al.   CELL BIOLOGY INTERNATIONAL

The Interleukin 1β Pathway in the Pathogenesis of Osteoarthritis

(2008) Massoud Daheshia et al.   JOURNAL OF RHEUMATOLOGY

IGF-1 regulation of type II collagen and MMP-13 expression in rat endplate chondrocytes via distinct signaling pathways

(2008) M. Zhang et al.   OSTEOARTHRITIS AND CARTILAGE