CRISPR technology is revolutionizing the improvement of tomato and other fruit crops

CRISPR Crops: Plant Genome Editing Toward Disease Resistance

(2018) Thorsten Langner et al.   Annual Review of Phytopathology

CRISPR Mediated Genome Engineering and its Application in Industry

(2018) Saeed Kaboli et al.   CURRENT ISSUES IN MOLECULAR BIOLOGY

Efficient generation of pink-fruited tomatoes using CRISPR/Cas9 system

(2018) Lei Deng et al.   Journal of Genetics and Genomics

CRISPR/Cas approach: A new way of looking at plant-abiotic interactions

(2018) Muntazir Mushtaq et al.   JOURNAL OF PLANT PHYSIOLOGY

A Phytophthora palmivora Extracellular Cystatin-Like Protease Inhibitor Targets Papain to Contribute to Virulence on Papaya

(2018) Rebecca Gumtow et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

With a free pass, CRISPR-edited plants reach market in record time

(2018) Emily Waltz   NATURE BIOTECHNOLOGY

Evidence for a specific and critical role of mitogen-activated protein kinase 20 in uni-to-binucleate transition of microgametogenesis in tomato

(2018) Lifei Chen et al.   NEW PHYTOLOGIST

Genome editing in potato via CRISPR-Cas9 ribonucleoprotein delivery

(2018) Mariette Andersson et al.   PHYSIOLOGIA PLANTARUM

Using CRISPR/Cas9 genome editing in tomato to create a gibberellin-responsive dominant dwarf DELLA allele

(2018) Laurence Tomlinson et al.   PLANT BIOTECHNOLOGY JOURNAL

High-efficiency genome editing using a dmc1 promoter-controlled CRISPR/Cas9 system in maize

(2018) Chao Feng et al.   PLANT BIOTECHNOLOGY JOURNAL

Optimized paired-sgRNA/Cas9 cloning and expression cassette triggers high-efficiency multiplex genome editing in kiwifruit

(2018) Zupeng Wang et al.   PLANT BIOTECHNOLOGY JOURNAL

Efficient genome editing of wild strawberry genes, vector development and validation

(2018) Junhui Zhou et al.   PLANT BIOTECHNOLOGY JOURNAL

Activities and specificities of CRISPR-Cas9 and Cas12a nucleases for targeted mutagenesis in maize

(2018) Keunsub Lee et al.   PLANT BIOTECHNOLOGY JOURNAL

DELLA-ARF/IAA Interaction Mediates Crosstalk between Gibberellin and Auxin Signaling in Controlling Fruit Initiation in Solanum lycopersicum

(2018) Jianhong Hu et al.   PLANT CELL

Engineering herbicide-resistant watermelon variety through CRISPR/Cas9-mediated base-editing

(2018) Shouwei Tian et al.   PLANT CELL REPORTS

Efficient in planta gene targeting in Arabidopsis using egg cell-specific expression of the Cas9 nuclease of Staphylococcus aureus

(2018) Felix Wolter et al.   PLANT JOURNAL

CRISPR/Cas9-mediated mutagenesis of lncRNA1459 alters tomato fruit ripening

(2018) Ran Li et al.   PLANT JOURNAL

Generation of α-solanine-free hairy roots of potato by CRISPR/Cas9 mediated genome editing of the St16DOX gene

(2018) Masaru Nakayasu et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Application and development of genome editing technologies to the Solanaceae plants

(2018) Tsuyoshi Yamamoto et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Genome Editing: Targeting Susceptibility Genes for Plant Disease Resistance

(2018) Syed Shan-e-Ali Zaidi et al.   TRENDS IN BIOTECHNOLOGY

Advances in Industrial Biotechnology Using CRISPR-Cas Systems

(2018) Paul D. Donohoue et al.   TRENDS IN BIOTECHNOLOGY

A Novel Tomato Fusarium Wilt Tolerance Gene

(2018) Cahya Prihatna et al.   Frontiers in Microbiology

Application of CRISPR/Cas9 Genome Editing Technology for the Improvement of Crops Cultivated in Tropical Climates: Recent Progress, Prospects, and Challenges

(2018) Effi Haque et al.   Frontiers in Plant Science

Lycopene Is Enriched in Tomato Fruit by CRISPR/Cas9-Mediated Multiplex Genome Editing

(2018) Xindi Li et al.   Frontiers in Plant Science

Transient Expression of CRISPR/Cas9 Machinery Targeting TcNPR3 Enhances Defense Response in Theobroma cacao

(2018) Andrew S. Fister et al.   Frontiers in Plant Science

Efficient Multiplex Genome Editing Induces Precise, and Self-Ligated Type Mutations in Tomato Plants

(2018) Ryosuke Hashimoto et al.   Frontiers in Plant Science

The Application of a Meiocyte-Specific CRISPR/Cas9 (MSC) System and a Suicide-MSC System in Generating Inheritable and Stable Mutations in Arabidopsis

(2018) Penghui Xu et al.   Frontiers in Plant Science

A novel DCL2-dependent miRNA pathway in tomato affects susceptibility to RNA viruses

(2018) Zhengming Wang et al.   GENES & DEVELOPMENT

Knockout of SlMAPK3 Reduced Disease Resistance to Botrytis cinerea in Tomato Plants

(2018) Shujuan Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

SlERF2 Is Associated with Methyl Jasmonate-Mediated Defense Response against Botrytis cinerea in Tomato Fruit

(2018) Wenqing Yu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Reduction of Tomato-Plant Chilling Tolerance by CRISPR–Cas9-Mediated SlCBF1 Mutagenesis

(2018) Rui Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

CRISPR/Cas9-introduced single and multiple mutagenesis in strawberry

(2018) Sinian Xing et al.   Journal of Genetics and Genomics

CRISPR plants now subject to tough GM laws in European Union

(2018) Ewen Callaway   NATURE

Design of a bacterial speck resistant tomato by CRISPR/Cas9-mediated editing of SlJAZ2

(2018) Andrés Ortigosa et al.   PLANT BIOTECHNOLOGY JOURNAL

The Enhancement of Plant Disease Resistance Using CRISPR/Cas9 Technology

(2018) Virginia M. G. Borrelli et al.   Frontiers in Plant Science

Tomato DCL2b is required for the biosynthesis of 22-nt small RNAs, the resulting secondary siRNAs, and the host defense against ToMV

(2018) Tian Wang et al.   Horticulture Research

Genome-wide identification of long non-coding RNA targets of the tomato MADS box transcription factor RIN and function analysis

(2018) Tongtong Yu et al.   ANNALS OF BOTANY

Reporter gene expression reveals precise auxin synthesis sites during fruit and root development in wild strawberry

(2018) Jia Feng et al.   JOURNAL OF EXPERIMENTAL BOTANY

Functional analysis of the TM6 MADS-box gene in the octoploid strawberry by CRISPR/Cas9-directed mutagenesis

(2018) Carmen Martín-Pizarro et al.   JOURNAL OF EXPERIMENTAL BOTANY

Domestication of wild tomato is accelerated by genome editing

(2018) Tingdong Li et al.   NATURE BIOTECHNOLOGY

De novo domestication of wild tomato using genome editing

(2018) Agustin Zsögön et al.   NATURE BIOTECHNOLOGY

TIR-NB-LRR immune receptor SOC3 pairs with truncated TIR-NB protein CHS1 or TN2 to monitor the homeostasis of E3 ligase SAUL1

(2018) Wanwan Liang et al.   NEW PHYTOLOGIST

Mutagenesis of kiwifruit CENTRORADIALIS -like genes transforms a climbing woody perennial with long juvenility and axillary flowering into a compact plant with rapid terminal flowering

(2018) Erika Varkonyi-Gasic et al.   PLANT BIOTECHNOLOGY JOURNAL

Development and Validation of an Effective CRISPR/Cas9 Vector for Efficiently Isolating Positive Transformants and Transgene-Free Mutants in a Wide Range of Plant Species

(2018) Ting Tang et al.   Frontiers in Plant Science

CRISPR/Cas9-mediated efficient editing in phytoene desaturase (PDS) demonstrates precise manipulation in banana cv. Rasthali genome

(2017) Navneet Kaur et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

Reduced Drought Tolerance by CRISPR/Cas9-Mediated SlMAPK3 Mutagenesis in Tomato Plants

(2017) Liu Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

CRISPR/Cas9-mediated genome editing in plants

(2017) Xuejun Liu et al.   METHODS

Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes

(2017) Gaelen T. Hess et al.   MOLECULAR CELL

Engineering Non-transgenic Gynoecious Cucumber Using an Improved Transformation Protocol and Optimized CRISPR/Cas9 System

(2017) Bowen Hu et al.   Molecular Plant

Fixing the tomato: CRISPR edits correct plant-breeding snafu

(2017) Heidi Ledford   NATURE

RNA targeting with CRISPR–Cas13

(2017) Omar O. Abudayyeh et al.   NATURE

Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion

(2017) Yuan Zong et al.   NATURE BIOTECHNOLOGY

Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion

(2017) Zenpei Shimatani et al.   NATURE BIOTECHNOLOGY

Genomic prediction unifies animal and plant breeding programs to form platforms for biological discovery

(2017) John M Hickey et al.   NATURE GENETICS

The Use of Grafting to Study Systemic Signaling in Plants

(2017) Hiroki Tsutsui et al.   PLANT AND CELL PHYSIOLOGY

CRISPR/Cas9-mediated efficient targeted mutagenesis in grape in the first generation

(2017) Xianhang Wang et al.   PLANT BIOTECHNOLOGY JOURNAL

Multiplexed CRISPR/Cas9-mediated metabolic engineering of γ-aminobutyric acid levels in Solanum lycopersicum

(2017) Rui Li et al.   PLANT BIOTECHNOLOGY JOURNAL

Engineering canker-resistant plants through CRISPR/Cas9-targeted editing of the susceptibility gene CsLOB1 promoter in citrus

(2017) Aihong Peng et al.   PLANT BIOTECHNOLOGY JOURNAL

An InDel in the Promoter of Al-ACTIVATED MALATE TRANSPORTER9 Selected during Tomato Domestication Determines Fruit Malate Contents and Aluminum Tolerance

(2017) Jie Ye et al.   PLANT CELL

Rapid and efficient CRISPR/Cas9 gene editing in Citrus using the YAO promoter

(2017) Fei Zhang et al.   PLANT CELL REPORTS

Genome editing as a tool to achieve the crop ideotype and de novo domestication of wild relatives: Case study in tomato

(2017) Agustin Zsögön et al.   PLANT SCIENCE

Critical roles of DNA demethylation in the activation of ripening-induced genes and inhibition of ripening-repressed genes in tomato fruit

(2017) Zhaobo Lang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EIN2 mediates direct regulation of histone acetylation in the ethylene response

(2017) Fan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome editors take on crops

(2017) Armin Scheben et al.   SCIENCE

Targeted recombination between homologous chromosomes for precise breeding in tomato

(2017) Shdema Filler Hayut et al.   Nature Communications

CRISPR/Cpf1-mediated DNA-free plant genome editing

(2017) Hyeran Kim et al.   Nature Communications

Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes

(2017) Zhen Liang et al.   Nature Communications

Gene Editing and Crop Improvement Using CRISPR-Cas9 System

(2017) Leena Arora et al.   Frontiers in Plant Science

CRISPR/Cas9 Mediated Genome Engineering for Improvement of Horticultural Crops

(2017) Suhas G. Karkute et al.   Frontiers in Plant Science

CRISPR/Cas9: A Practical Approach in Date Palm Genome Editing

(2017) Muhammad N. Sattar et al.   Frontiers in Plant Science

Genetic engineering strategies for biotic and abiotic stress tolerance and quality enhancement in horticultural crops: a comprehensive review

(2017) Nehanjali Parmar et al.   3 Biotech

Genetic engineering strategies for biotic and abiotic stress tolerance and quality enhancement in horticultural crops: a comprehensive review

(2017) Nehanjali Parmar et al.   3 Biotech

Rapid generation of a transgene-free powdery mildew resistant tomato by genome deletion

(2017) Vladimir Nekrasov et al.   Scientific Reports

Rapid breeding of parthenocarpic tomato plants using CRISPR/Cas9

(2017) Risa Ueta et al.   Scientific Reports

Natural and induced loss of function mutations in SlMBP21 MADS-box gene led to jointless-2 phenotype in tomato

(2017) Maria Victoria Gomez Roldan et al.   Scientific Reports

Efficient increase of ɣ-aminobutyric acid (GABA) content in tomato fruits by targeted mutagenesis

(2017) Satoko Nonaka et al.   Scientific Reports

CRISPR/Cas9-induced Targeted Mutagenesis and Gene Replacement to Generate Long-shelf Life Tomato Lines

(2017) Qing-hui Yu et al.   Scientific Reports

CRISPR/Cas9 in Genome Editing and Beyond

(2016) Haifeng Wang et al.   Annual Review of Biochemistry

Current status of potential applications of repurposed Cas9 for structural and functional genomics of plants

(2016) Kunal Seth et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High-efficiency CRISPR/Cas9 multiplex gene editing using the glycine tRNA-processing system-based strategy in maize

(2016) Weiwei Qi et al.   BMC BIOTECHNOLOGY

Bioactive compounds in banana and their associated health benefits – A review

(2016) Balwinder Singh et al.   FOOD CHEMISTRY

Control of inflorescence architecture in tomato by BTB/POZ transcriptional regulators

(2016) Cao Xu et al.   GENES & DEVELOPMENT

Adaptation in CRISPR-Cas Systems

(2016) Samuel H. Sternberg et al.   MOLECULAR CELL

Expanding the Range of CRISPR/Cas9 Genome Editing in Rice

(2016) Xixun Hu et al.   Molecular Plant

Development of broad virus resistance in non-transgenic cucumber using CRISPR/Cas9 technology

(2016) Jeyabharathy Chandrasekaran et al.   MOLECULAR PLANT PATHOLOGY

Gene-edited CRISPR mushroom escapes US regulation

(2016) Emily Waltz   NATURE

Bypassing GMO regulations with CRISPR gene editing

(2016) Jungeun Kim et al.   NATURE BIOTECHNOLOGY

Erratum: Corrigendum: Genetic improvement of tomato by targeted control of fruit softening

(2016) Selman Uluisik et al.   NATURE BIOTECHNOLOGY

Variation in the flowering gene SELF PRUNING 5G promotes day-neutrality and early yield in tomato

(2016) Sebastian Soyk et al.   NATURE GENETICS

CRISPR–Cas adaptation: insights into the mechanism of action

(2016) Gil Amitai et al.   NATURE REVIEWS MICROBIOLOGY

JAZ2 controls stomata dynamics during bacterial invasion

(2016) Selena Gimenez-Ibanez et al.   NEW PHYTOLOGIST

CRISPR-Cas: biology, mechanisms and relevance

(2016) Frank Hille et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Precision Targeted Mutagenesis via Cas9 Paired Nickases in Rice

(2016) Masafumi Mikami et al.   PLANT AND CELL PHYSIOLOGY

Tomato facultative parthenocarpy results from SlAGAMOUS-LIKE 6 loss of function

(2016) Chen Klap et al.   PLANT BIOTECHNOLOGY JOURNAL

AnAgrobacterium-delivered CRISPR/Cas9 system for high-frequency targeted mutagenesis in maize

(2016) Si Nian Char et al.   PLANT BIOTECHNOLOGY JOURNAL

High efficiency of targeted mutagenesis in arabidopsis via meiotic promoter-driven expression of Cas9 endonuclease

(2016) Ayman Eid et al.   PLANT CELL REPORTS

Efficient CRISPR/Cas9-based gene knockout in watermelon

(2016) Shouwei Tian et al.   PLANT CELL REPORTS

Efficient and transgene-free genome editing in wheat through transient expression of CRISPR/Cas9 DNA or RNA

(2016) Yi Zhang et al.   Nature Communications

DNA-Free Genetically Edited Grapevine and Apple Protoplast Using CRISPR/Cas9 Ribonucleoproteins

(2016) Mickael Malnoy et al.   Frontiers in Plant Science

CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo

(2016) Hong Chang et al.   Scientific Reports

Highly specific targeted mutagenesis in plants using Staphylococcus aureus Cas9

(2016) Hidetaka Kaya et al.   Scientific Reports

Optimization of CRISPR/Cas9 genome editing to modify abiotic stress responses in plants

(2016) Yuriko Osakabe et al.   Scientific Reports

Efficient Genome Editing in Apple Using a CRISPR/Cas9 system

(2016) Chikako Nishitani et al.   Scientific Reports

Efficient targeted mutagenesis of rice and tobacco genomes using Cpf1 from Francisella novicida

(2016) Akira Endo et al.   Scientific Reports

CRISPR/Cas9-mediated mutagenesis of the RIN locus that regulates tomato fruit ripening

(2015) Yasuhiro Ito et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High-Efficiency Genome Editing in Arabidopsis Using YAO Promoter-Driven CRISPR/Cas9 System

(2015) Liuhua Yan et al.   Molecular Plant

A Robust CRISPR/Cas9 System for Convenient, High-Efficiency Multiplex Genome Editing in Monocot and Dicot Plants

(2015) Xingliang Ma et al.   Molecular Plant

The emergence of agbiogenerics

(2015) David J Jefferson et al.   NATURE BIOTECHNOLOGY

DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins

(2015) Je Wook Woo et al.   NATURE BIOTECHNOLOGY

Development of germ-line-specific CRISPR-Cas9 systems to improve the production of heritable gene modifications inArabidopsis

(2015) Yanfei Mao et al.   PLANT BIOTECHNOLOGY JOURNAL

Modification of the PthA4 effector binding elements in Type I CsLOB1 promoter using Cas9/sgRNA to produce transgenic Duncan grapefruit alleviating XccΔpthA4:dCsLOB1.3 infection

(2015) Hongge Jia et al.   PLANT BIOTECHNOLOGY JOURNAL

Highly efficient heritable plant genome engineering using Cas9 orthologues fromStreptococcus thermophilusandStaphylococcus aureus

(2015) Jeannette Steinert et al.   PLANT JOURNAL

Physiological changes in fruit ripening caused by overexpression of tomato SlAN2, an R2R3-MYB factor

(2015) Xia Meng et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system

(2015) Kabin Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Looking forward to genetically edited fruit crops

(2015) Chidananda Nagamangala Kanchiswamy et al.   TRENDS IN BIOTECHNOLOGY

Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation

(2015) Zhi-Ping Wang et al.   GENOME BIOLOGY

Efficient CRISPR/Cas9-mediated Targeted Mutagenesis in Populus in the First Generation

(2015) Di Fan et al.   Scientific Reports

Different roles for RNA silencing and RNA processing components in virus recovery and virus-induced gene silencing in plants

(2014) Xiaofang Ma et al.   JOURNAL OF EXPERIMENTAL BOTANY

Consumer Attitudes and Preferences for Fresh Market Tomatoes

(2014) A.E. Oltman et al.   JOURNAL OF FOOD SCIENCE

Genomic analyses provide insights into the history of tomato breeding

(2014) Tao Lin et al.   NATURE GENETICS

RNA-guided transcriptional regulationin plantavia synthetic dCas9-based transcription factors

(2014) Agnieszka Piatek et al.   PLANT BIOTECHNOLOGY JOURNAL

DOWNY MILDEW RESISTANT 6 and DMR6-LIKE OXYGENASE 1 are partially redundant but distinct suppressors of immunity in Arabidopsis

(2014) Tieme Zeilmaker et al.   PLANT JOURNAL

Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering inArabidopsis thaliana

(2014) Friedrich Fauser et al.   PLANT JOURNAL

CRISPR/Cas9-mediated targeted mutagenesis in Nicotiana tabacum

(2014) Junping Gao et al.   PLANT MOLECULAR BIOLOGY

Efficient Gene Editing in Tomato in the First Generation Using the Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-Associated9 System

(2014) C. Brooks et al.   PLANT PHYSIOLOGY

Site-directed mutagenesis in Arabidopsis thaliana using dividing tissue-targeted RGEN of the CRISPR/Cas system to generate heritable null alleles

(2014) Youbong Hyun et al.   PLANTA

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

Structure of the CRISPR Interference Complex CSM Reveals Key Similarities with Cascade

(2013) Christophe Rouillon et al.   MOLECULAR CELL

Targeted genome modification of crop plants using a CRISPR-Cas system

(2013) Qiwei Shan et al.   NATURE BIOTECHNOLOGY

Evolution of crop species: genetics of domestication and diversification

(2013) Rachel S. Meyer et al.   NATURE REVIEWS GENETICS

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Innovation trends in the food industry: The case of functional foods

(2013) Barbara Bigliardi et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Genetically modified foods: safety, risks and public concerns—a review

(2012) A. S. Bawa et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Functional specialization of duplicated AP3-like genes inMedicago truncatula

(2012) Edelín Roque et al.   PLANT JOURNAL

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

(2012) G. Gasiunas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cas5d Protein Processes Pre-crRNA and Assembles into a Cascade-like Interference Complex in Subtype I-C/Dvulg CRISPR-Cas System

(2012) Ki Hyun Nam et al.   STRUCTURE

Estimates and implications of the costs of compliance with biosafety regulations in developing countries

(2012) Jose Falck-Zepeda et al.   GM Crops & Food-Biotechnology in Agriculture and the Food Chain

From forest to field: Perennial fruit crop domestication

(2011) Allison J. Miller et al.   AMERICAN JOURNAL OF BOTANY

Date Fruits (Phoenix dactyliferaLinn): An Emerging Medicinal Food

(2011) Praveen K. Vayalil   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Breeding Technologies to Increase Crop Production in a Changing World

(2010) M. Tester et al.   SCIENCE

Biochemical and Molecular Analysis of Pink Tomatoes: Deregulated Expression of the Gene Encoding Transcription Factor SlMYB12 Leads to Pink Tomato Fruit Color

(2009) A.-R. Ballester et al.   PLANT PHYSIOLOGY