STAT3 Activation in Combination with NF-KappaB Inhibition Induces Tolerogenic Dendritic Cells with High Therapeutic Potential to Attenuate Collagen-Induced Arthritis

Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity

(2019) Mattias N.D. Svensson et al.   JOURNAL OF CLINICAL INVESTIGATION

Smoking promotes exacerbated inflammatory features in dendritic cells of Chilean rheumatoid arthritis patients

(2018) Carolina Prado et al.   REVISTA MEDICA DE CHILE

Dopaminergic Stimulation of Myeloid Antigen-Presenting Cells Attenuates Signal Transducer and Activator of Transcription 3-Activation Favouring the Development of Experimental Autoimmune Encephalomyelitis

(2018) Carolina Prado et al.   Frontiers in Immunology

Diagnosis and Management of Rheumatoid Arthritis

(2018) Daniel Aletaha et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Targeting of tolerogenic dendritic cells towards heat-shock proteins: a novel therapeutic strategy for autoimmune diseases?

(2017) Manon A. A. Jansen et al.   IMMUNOLOGY

1,25-dihydroxyvitamin D3 -induced dendritic cells suppress experimental autoimmune encephalomyelitis by increasing proportions of the regulatory lymphocytes and reducing T helper type 1 and type 17 cells

(2017) Zhongxiang Xie et al.   IMMUNOLOGY

Amelioration of collagen-induced arthritis using antigen-loaded dendritic cells modified with NF-κB decoy oligodeoxynucleotides

(2017) Hongmei Jiang et al.   Drug Design Development and Therapy

The Immunomodulatory Potential of tolDCs Loaded with Heat Shock Proteins

(2017) Willem van Eden et al.   Frontiers in Immunology

Clinical Tolerogenic Dendritic Cells: Exploring Therapeutic Impact on Human Autoimmune Disease

(2017) Brett Eugene Phillips et al.   Frontiers in Immunology

Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis

(2016) G M Bell et al.   ANNALS OF THE RHEUMATIC DISEASES

Increased expression with differential subcellular location of cytidine deaminase APOBEC3G in human CD4+ T-cell activation and dendritic cell maturation

(2016) Harold Oliva et al.   IMMUNOLOGY AND CELL BIOLOGY

Inhibition of RelA expression via RNA interference induces immune tolerance in a rat keratoplasty model

(2016) Jize Yang et al.   MOLECULAR IMMUNOLOGY

Therapeutic Effect of Ergotope Peptides on Collagen-Induced Arthritis by Downregulation of Inflammatory and Th1/Th17 Responses and Induction of Regulatory T Cells

(2016) Xiaoyin Niu et al.   MOLECULAR MEDICINE

JAK1/STAT3 activation directly inhibits IL-12 production in dendritic cells by preventing CDK9/P-TEFb recruitment to the p35 promoter

(2015) Andreas H. Wagner et al.   BIOCHEMICAL PHARMACOLOGY

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

(2015) Helen Benham et al.   Science Translational Medicine

Soluble PD-1 aggravates progression of collagen-induced arthritis through Th1 and Th17 pathways

(2015) Cuiping Liu et al.   ARTHRITIS RESEARCH & THERAPY

Vitamin D3 Induces Tolerance in Human Dendritic Cells by Activation of Intracellular Metabolic Pathways

(2015) Gabriela Bomfim Ferreira et al.   Cell Reports

Antigen-Specific Tolerogenic Dendritic Cells Ameliorate the Severity of Murine Collagen-Induced Arthritis

(2015) Bin Ning et al.   PLoS One

Tolerogenic dendritic cells produced by lentiviral-mediated CD40- and interleukin-23p19-specific shRNA can ameliorate experimental autoimmune encephalomyelitis by suppressing T helper type 17 cells

(2014) T. Kalantari et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Transcription Factor IRF8 Activates Integrin-Mediated TGF-β Signaling and Promotes Neuroinflammation

(2014) Yuko Yoshida et al.   IMMUNITY

Tolerogenic dendritic cells modified by tacrolimus suppress CD4+ T-cell proliferation and inhibit collagen-induced arthritis in mice

(2014) Yana Ren et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Lipopolysaccharide-Activated IL-10-Secreting Dendritic Cells Suppress Experimental Autoimmune Uveoretinitis by MHCII-Dependent Activation of CD62L-Expressing Regulatory T Cells

(2014) A. W. T. Lau et al.   JOURNAL OF IMMUNOLOGY

Suppression of Murine Colitis and its Associated Cancer by Carcinoembryonic Antigen-Specific Regulatory T Cells

(2014) Dan Blat et al.   MOLECULAR THERAPY

Tolerogenic Splenic IDO+Dendritic Cells from the Mice Treated with Induced-Treg Cells Suppress Collagen-Induced Arthritis

(2014) Jie Yang et al.   Journal of Immunology Research

Molecular programming of steady-state dendritic cells: impact on autoimmunity and tumor immune surveillance

(2013) Dylan J. Johnson et al.   Annals of the New York Academy of Sciences

T-bet is essential for Th1-mediated, but not Th17-mediated, CNS autoimmune disease

(2013) Richard A. O'Connor et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cell-extrinsic CTLA4-mediated regulation of dendritic cell maturation depends on STAT3

(2013) Aleksandra Kowalczyk et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dopamine Receptor D3 Expressed on CD4+ T Cells Favors Neurodegeneration of Dopaminergic Neurons during Parkinson's Disease

(2013) H. Gonzalez et al.   JOURNAL OF IMMUNOLOGY

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

(2013) Noriko Komatsu et al.   NATURE MEDICINE

A Mouse Model of Adoptive Immunotherapeutic Targeting of Autoimmune Arthritis Using Allo-Tolerogenic Dendritic Cells

(2013) Jie Yang et al.   PLoS One

Autoimmune Memory T Helper 17 Cell Function and Expansion Are Dependent on Interleukin-23

(2013) Christopher J. Haines et al.   Cell Reports

Stimulation of Dopamine Receptor D5 Expressed on Dendritic Cells Potentiates Th17-Mediated Immunity

(2012) C. Prado et al.   JOURNAL OF IMMUNOLOGY

CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

(2012) Moa Fransson et al.   Journal of Neuroinflammation

Dendritic Cells Transduced With Lentiviral Vectors Expressing VIP Differentiate Into VIP-secreting Tolerogenic-like DCs

(2010) Miguel G Toscano et al.   MOLECULAR THERAPY

Plasticity of CD4+ T Cell Lineage Differentiation

(2009) Liang Zhou et al.   IMMUNITY

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

(2009) Caspar Ohnmacht et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans

(2009) P Bonifazi et al.   Mucosal Immunology

Th17 cells in immunity and autoimmunity

(2008) M Oukka   ANNALS OF THE RHEUMATIC DISEASES

Th17 Cell Differentiation: The Long and Winding Road

(2008) Mandy J. McGeachy et al.   IMMUNITY

Role of Th1 and Th17 cells in organ-specific autoimmunity

(2008) Valérie Dardalhon et al.   JOURNAL OF AUTOIMMUNITY