CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

Intranasal delivery of stem cells to the brain

(2011) Yongjun Jiang et al.   Expert Opinion on Drug Delivery

T regulatory cells lacking CD25 are increased in MS during relapse

(2010) Moa Fransson et al.   AUTOIMMUNITY

834 Useful Evaluation of Thromboelastography for Coagulation Disorders in Critically Ill Patients

(2010) J C S Herrera et al.   PEDIATRIC RESEARCH

Human ROR t+ TH17 cells preferentially differentiate from naive FOXP3+Treg in the presence of lineage-specific polarizing factors

(2010) D. Valmori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells

(2009) Piotr Trzonkowski et al.   CLINICAL IMMUNOLOGY

Intranasal delivery of cells to the brain

(2009) Lusine Danielyan et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Curing CNS autoimmune disease with myelin-reactive Foxp3+Treg

(2009) Leigh A. Stephens et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Amelioration of Colitis by Genetically Engineered Murine Regulatory T Cells Redirected by Antigen-Specific Chimeric Receptor

(2009) Eran Elinav et al.   GASTROENTEROLOGY

Redirecting human CD4+CD25+ regulatory T cells from the peripheral blood with pre-defined target specificity

(2009) A A Hombach et al.   GENE THERAPY

Engineered regulatory T cells prevent graft-versus-host disease while sparing the graft-versus-leukemia effect after bone marrow transplantation

(2009) Jiang Cao et al.   LEUKEMIA RESEARCH

FOXP3 and the regulation of Treg/Th17 differentiation

(2009) Steven F. Ziegler et al.   MICROBES AND INFECTION

Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis

(2009) Graham P. Wright et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redirection of Regulatory T Cells With Predetermined Specificity for the Treatment of Experimental Colitis in Mice

(2008) Eran Elinav et al.   GASTROENTEROLOGY

Compromised CD4+ CD25highregulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level

(2007) Koen Venken et al.   IMMUNOLOGY