JAK1/STAT3 activation directly inhibits IL-12 production in dendritic cells by preventing CDK9/P-TEFb recruitment to the p35 promoter

Title
JAK1/STAT3 activation directly inhibits IL-12 production in dendritic cells by preventing CDK9/P-TEFb recruitment to the p35 promoter
Authors
Keywords
Dendritic cells, JAK inhibitor, Interleukin-12, JAK-STAT pathway, CDK9
Journal
BIOCHEMICAL PHARMACOLOGY
Volume 96, Issue 1, Pages 52-64
Publisher
Elsevier BV
Online
2015-04-28
DOI
10.1016/j.bcp.2015.04.019

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