Past and Current Perspectives in Modeling Bacteria and Blood–Brain Barrier Interactions

Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection

(2019) Sara F. Martins Gomes et al.   Frontiers in Microbiology

The blood-brain barrier internalises Cryptococcus neoformans via the EphA2-tyrosine kinase receptor

(2018) Phylicia A. Aaron et al.   CELLULAR MICROBIOLOGY

Bridging barriers: a comparative look at the blood–brain barrier across organisms

(2018) Natasha M. O'Brown et al.   GENES & DEVELOPMENT

Characterization of a Two-Component System Transcriptional Regulator, LtdR, That Impacts Group B Streptococcal Colonization and Disease

(2018) Liwen Deng et al.   INFECTION AND IMMUNITY

Advances in Meningeal Immunity

(2018) Rejane Rua et al.   TRENDS IN MOLECULAR MEDICINE

Proteomic and bioinformatic pipeline to screen the ligands of S. pneumoniae interacting with human brain microvascular endothelial cells

(2018) Irene Jiménez-Munguía et al.   Scientific Reports

Brucella abortus Traverses Brain Microvascular Endothelial Cells Using Infected Monocytes as a Trojan Horse

(2018) María C. Miraglia et al.   Frontiers in Cellular and Infection Microbiology

Characterization of a Listeria monocytogenes meningitis mouse model

(2018) Merel M. Koopmans et al.   Journal of Neuroinflammation

A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection

(2018) Elva Bonifácio Andrade et al.   Nature Communications

Reverse genetic system, genetically stable reporter viruses and packaged subgenomic replicon based on a Brazilian Zika virus isolate

(2017) Margit Mutso et al.   JOURNAL OF GENERAL VIROLOGY

An isogenic blood-brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells

(2017) Scott G. Canfield et al.   JOURNAL OF NEUROCHEMISTRY

A journey into the brain: insight into how bacterial pathogens cross blood–brain barriers

(2017) Mathieu Coureuil et al.   NATURE REVIEWS MICROBIOLOGY

Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits

(2017) Ryan G. Lim et al.   Cell Reports

Morbid Sequences Suggest Molecular Mimicry between Microbial Peptides and Self-Antigens: A Possibility of Inciting Autoimmunity

(2017) Susanta Pahari et al.   Frontiers in Microbiology

Molecular mechanisms involved in the interaction of Neisseria meningitidis with cells of the human blood–cerebrospinal fluid barrier

(2017) Alexandra Schubert-Unkmeir   Pathogens and Disease

Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells

(2017) Antje Appelt-Menzel et al.   Stem Cell Reports

Modeling Group B Streptococcus and Blood-Brain Barrier Interaction by Using Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells

(2017) Brandon J. Kim et al.   mSphere

Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells

(2017) Tongcheng Qian et al.   Science Advances

Host–pathogen interactions in bacterial meningitis

(2016) Kelly S. Doran et al.   ACTA NEUROPATHOLOGICA

Immortalized endothelial cell lines for in vitro blood–brain barrier models: A systematic review

(2016) Nurul Adhwa Rahman et al.   BRAIN RESEARCH

Microglia activation in a pediatric rabbit model of tuberculous meningitis

(2016) Elizabeth W. Tucker et al.   Disease Models & Mechanisms

In vitro models of the blood–brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use

(2016) Hans C Helms et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model

(2016) Kin Ki Jim et al.   Journal of Neuroinflammation

Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells

(2016) Matthew J. Stebbins et al.   METHODS

Analysis of Cancer-Targeting Alkylphosphocholine Analogue Permeability Characteristics Using a Human Induced Pluripotent Stem Cell Blood–Brain Barrier Model

(2016) Paul A. Clark et al.   MOLECULAR PHARMACEUTICS

Uncovering Listeria monocytogenes hypervirulence by harnessing its biodiversity

(2016) Mylène M Maury et al.   NATURE GENETICS

Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier

(2016) Ruicheng Yang et al.   Oncotarget

Bacterial induction of Snail1 contributes to blood-brain barrier disruption

(2015) Brandon J. Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential permissivity of human cerebrovascular endothelial cells to enterovirus infection and specificities of serotype EV-A71 in crossing an in vitro model of the human blood–brain barrier

(2015) Romain Volle et al.   JOURNAL OF GENERAL VIROLOGY

Streptococcus agalactiae infection in zebrafish larvae

(2015) Brandon J. Kim et al.   MICROBIAL PATHOGENESIS

Group B Streptococcal Infection and Activation of Human Astrocytes

(2015) Terri D. Stoner et al.   PLoS One

Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular Pathology

(2015) Hansang Cho et al.   Scientific Reports

Interaction of fibrinogen and muramidase-released protein promotes the development of Streptococcus suis meningitis

(2015) Junping Wang et al.   Frontiers in Microbiology

Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum

(2014) L. M. van Leeuwen et al.   Disease Models & Mechanisms

Astrocytes produce IL-19 in response to bacterial challenge and are sensitive to the immunosuppressive effects of this IL-10 family member

(2014) Ian D. Cooley et al.   GLIA

Pathogenic Neisseria meningitidis utilizes CD147 for vascular colonization

(2014) Sandra C Bernard et al.   NATURE MEDICINE

P. falciparum Isolate-Specific Distinct Patterns of Induced Apoptosis in Pulmonary and Brain Endothelial Cells

(2014) Nadine N'Dilimabaka et al.   PLoS One

A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells

(2014) Romeo Cecchelli et al.   PLoS One

A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources

(2014) Ethan S. Lippmann et al.   Scientific Reports

Modeling Tuberculosis in Nonhuman Primates

(2014) C. A. Scanga et al.   Cold Spring Harbor Perspectives in Medicine

Animal models for oral transmission of Listeria monocytogenes

(2014) Sarah E. F. D'Orazio   Frontiers in Cellular and Infection Microbiology

Human Streptococcus agalactiae strains in aquatic mammals and fish

(2013) Christian MJ Delannoy et al.   BMC MICROBIOLOGY

Group B Streptococcus Late-Onset Disease: 2003-2010

(2013) A. Berardi et al.   PEDIATRICS

Serotype-Specific Changes in Invasive Pneumococcal Disease after Pneumococcal Conjugate Vaccine Introduction: A Pooled Analysis of Multiple Surveillance Sites

(2013) Daniel R. Feikin et al.   PLOS MEDICINE

In Vivo Adaptation and Persistence of Neisseria meningitidis within the Nasopharyngeal Mucosa

(2013) Kay O. Johswich et al.   PLoS Pathogens

Adult zebrafish model of bacterial meningitis in Streptococcus agalactiae infection

(2012) Hayley Patterson et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Innate Immune Response to Streptococcus iniae Infection in Zebrafish Larvae

(2012) Elizabeth A. Harvie et al.   INFECTION AND IMMUNITY

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

(2012) Ethan S Lippmann et al.   NATURE BIOTECHNOLOGY

Group B Streptococcus Interactions with Human Meningeal Cells and Astrocytes In Vitro

(2012) Khalil Alkuwaity et al.   PLoS One

Viral disruption of the blood–brain barrier

(2012) Katherine R. Spindler et al.   TRENDS IN MICROBIOLOGY

Pathogenesis and Pathophysiology of Pneumococcal Meningitis

(2011) B. B. Mook-Kanamori et al.   CLINICAL MICROBIOLOGY REVIEWS

Meningococcus Hijacks a β2-Adrenoceptor/β-Arrestin Pathway to Cross Brain Microvasculature Endothelium

(2010) Mathieu Coureuil et al.   CELL

Activation of brain endothelium by pneumococcal neuraminidase NanA promotes bacterial internalization

(2010) Anirban Banerjee et al.   CELLULAR MICROBIOLOGY

Deciphering the Roles of Outer Membrane Protein A Extracellular Loops in the Pathogenesis ofEscherichia coliK1 Meningitis

(2010) Rahul Mittal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-10 administration reduces PGE-2 levels and promotes CR3-mediated clearance ofEscherichia coliK1 by phagocytes in meningitis

(2010) Rahul Mittal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bacterial Pore-Forming Cytolysins Induce Neuronal Damage in a Rat Model of Neonatal Meningitis

(2010) Anja Reiß et al.   JOURNAL OF INFECTIOUS DISEASES

The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion

(2009) Satoshi Uchiyama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

The blood–brain and the blood–cerebrospinal fluid barriers: function and dysfunction

(2009) Britta Engelhardt et al.   Seminars in Immunopathology

Animal Models of Streptococcus pneumoniae Disease

(2008) D. Chiavolini et al.   CLINICAL MICROBIOLOGY REVIEWS

Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport

(2008) S. Syvanen et al.   DRUG METABOLISM AND DISPOSITION