Mouse TRPA1 function and membrane localization are modulated by direct interactions with cholesterol

TRP Channels as Sensors of Chemically-Induced Changes in Cell Membrane Mechanical Properties

(2019) Justyna Startek et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Carboxamido steroids inhibit the opening properties of Transient Receptor Potential ion channels by lipid raft modulation

(2018) Eva Saghy et al.   JOURNAL OF LIPID RESEARCH

A TRP channel trio mediates acute noxious heat sensing

(2018) Ine Vandewauw et al.   NATURE

To flourish or perish: evolutionary TRiPs into the sensory biology of plant-herbivore interactions

(2018) Justyna B. Startek et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Differential interactions of bacterial lipopolysaccharides with lipid membranes: implications for TRPA1-mediated chemosensation

(2018) Justyna B. Startek et al.   Scientific Reports

Cholesterol regulates polymodal sensory transduction in Müller glia

(2017) Monika Lakk et al.   GLIA

Preferential selection of Arginine at the lipid-water-interface of TRPV1 during vertebrate evolution correlates with its snorkeling behaviour and cholesterol interaction

(2017) Somdatta Saha et al.   Scientific Reports

The N-terminal Ankyrin Repeat Domain Is Not Required for Electrophile and Heat Activation of the Purified Mosquito TRPA1 Receptor

(2016) Sabeen Survery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Agonist-induced sensitisation of the irritant receptor ion channel TRPA1

(2016) Jannis E. Meents et al.   JOURNAL OF PHYSIOLOGY-LONDON

VAMP7 regulates constitutive membrane incorporation of the cold-activated channel TRPM8

(2016) Debapriya Ghosh et al.   Nature Communications

Gustatory-mediated avoidance of bacterial lipopolysaccharides via TRPA1 activation in Drosophila

(2016) Alessia Soldano et al.   eLife

A mirror code for protein-cholesterol interactions in the two leaflets of biological membranes

(2016) Jacques Fantini et al.   Scientific Reports

Human TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity

(2016) Lavanya Moparthi et al.   Scientific Reports

Influence of membrane cholesterol in the molecular evolution and functional regulation of TRPV4

(2015) Shikha Kumari et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Erratum: Structure of the TRPA1 ion channel suggests regulatory mechanisms

(2015) Candice E. Paulsen et al.   NATURE

Evidence for the role of lipid rafts and sphingomyelin in Ca2+-gating of Transient Receptor Potential channels in trigeminal sensory neurons and peripheral nerve terminals

(2015) Éva Sághy et al.   PHARMACOLOGICAL RESEARCH

Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain

(2014) Lavanya Moparthi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins

(2014) Victor Meseguer et al.   Nature Communications

Cholesterol sensitises the transient receptor potential channel TRPV3 to lower temperatures and activator concentrations

(2013) Anke S. Klein et al.   CELL CALCIUM

Species differences and molecular determinant of TRPA1 cold sensitivity

(2013) Jun Chen et al.   Nature Communications

How cholesterol interacts with membrane proteins: an exploration of cholesterol-binding sites including CRAC, CARC, and tilted domains

(2013) Jacques Fantini et al.   Frontiers in Physiology

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Transient Receptor Potential Ankyrin 1 Channel Localized to Non-Neuronal Airway Cells Promotes Non-Neurogenic Inflammation

(2012) Romina Nassini et al.   PLoS One

Exploring the activation mechanism of TRPM8 channel by targeted MD simulations

(2011) Alessandro Pedretti et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors

(2011) Juliette Descoeur et al.   EMBO Molecular Medicine

Identification of a Binding Motif in the S5 Helix That Confers Cholesterol Sensitivity to the TRPV1 Ion Channel

(2011) Giovanni Picazo-Juárez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures, Biosynthesis, and Functions of Gangliosides-an Overview

(2011) Robert K. Yu et al.   Journal of Oleo Science

Research advances on flotillins

(2011) Feng Zhao et al.   Virology Journal

Lipid-dependent gating of a voltage-gated potassium channel

(2011) Hui Zheng et al.   Nature Communications

Pregnenolone Sulphate- and Cholesterol-Regulated TRPM3 Channels Coupled to Vascular Smooth Muscle Secretion and Contraction

(2010) Jacqueline Naylor et al.   CIRCULATION RESEARCH

Regulation of Nociceptive Transmission at the Periphery Via TRPA1-TRPV1 Interactions

(2010) Armen N. Akopian   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Irritating channels: the case of TRPA1

(2010) Bernd Nilius et al.   JOURNAL OF PHYSIOLOGY-LONDON

Transient receptor potential V1 regulates activation and modulation of transient receptor potential A1 by Ca2+

(2010) M.J. Patil et al.   NEUROSCIENCE

Comparative modeling of the quaternary structure for the human TRPM8 channel and analysis of its binding features

(2009) Alessandro Pedretti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Effect of lipid raft disruption on TRPV1 receptor activation of trigeminal sensory neurons and transfected cell line

(2009) Éva Szőke et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Differential Effect of Membrane Cholesterol Removal on μ- and δ-Opioid Receptors

(2009) Erica S. Levitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid Raft Segregation Modulates TRPM8 Channel Activity

(2009) Cruz Morenilla-Palao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Non-Neuronal Expression of Transient Receptor Potential Type A1 (TRPA1) in Human Skin

(2009) Ruzanna Atoyan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons

(2009) K. Y. Kwan et al.   JOURNAL OF NEUROSCIENCE

TRPA1 acts as a cold sensor in vitro and in vivo

(2009) Y. Karashima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transient receptor potential A1 mediates an osmotically activated ion channel

(2008) Xu-Feng Zhang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cholesterol-dependent Separation of the β2-Adrenergic Receptor from Its Partners Determines Signaling Efficacy

(2008) Stéphanie M. Pontier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingomyelinase acts by an area-activated mechanism on the liquid-expanded phase of sphingomyelin monolayers

(2008) Luisina De Tullio et al.   JOURNAL OF LIPID RESEARCH

An internal thermal sensor controlling temperature preference in Drosophila

(2008) Fumika N. Hamada et al.   NATURE

Intact Aδ-fibers up-regulate transient receptor potential A1 and contribute to cold hypersensitivity in neuropathic rats

(2008) G. Ji et al.   NEUROSCIENCE

TRPA1 receptor localisation in the human peripheral nervous system and functional studies in cultured human and rat sensory neurons

(2008) U. Anand et al.   NEUROSCIENCE LETTERS

Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators

(2008) Yuji Karashima et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY