The N-terminal Ankyrin Repeat Domain Is Not Required for Electrophile and Heat Activation of the Purified Mosquito TRPA1 Receptor

Human TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity

(2016) Lavanya Moparthi et al.   Scientific Reports

Understanding Thermosensitive Transient Receptor Potential Channels as Versatile Polymodal Cellular Sensors

(2015) Jacob K. Hilton et al.   BIOCHEMISTRY

Structure of the TRPA1 ion channel suggests regulatory mechanisms

(2015) Candice E. Paulsen et al.   NATURE

Peripheral thermosensation in mammals

(2014) Joris Vriens et al.   NATURE REVIEWS NEUROSCIENCE

Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six

(2014) Sairam Jabba et al.   NEURON

Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain

(2014) Lavanya Moparthi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRP Channels and Pain

(2013) David Julius   Annual Review of Cell and Developmental Biology

Protter: interactive protein feature visualization and integration with experimental proteomic data

(2013) Ulrich Omasits et al.   BIOINFORMATICS

Molecular Characterization of Larval Peripheral Thermosensory Responses of the Malaria Vector Mosquito Anopheles gambiae

(2013) Chao Liu et al.   PLoS One

Residues in the pore region ofDrosophilatransient receptor potential A1 dictate sensitivity to thermal stimuli

(2012) Hong Wang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Thermosensory and Nonthermosensory Isoforms of Drosophila melanogaster TRPA1 Reveal Heat-Sensor Domains of a ThermoTRP Channel

(2012) Lixian Zhong et al.   Cell Reports

Increasing gene dosage greatly enhances recombinant expression of aquaporins in Pichia pastoris

(2011) Kristina Nordén et al.   BMC BIOTECHNOLOGY

Modulation of TRPA1 thermal sensitivity enables sensory discrimination in Drosophila

(2011) Kyeongjin Kang et al.   NATURE

Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system

(2011) Peter Holzer   PHARMACOLOGY & THERAPEUTICS

Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli

(2011) J. F. Cordero-Morales et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A thermodynamic framework for understanding temperature sensing by transient receptor potential (TRP) channels

(2011) D. E. Clapham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The transient receptor potential family of ion channels

(2011) Bernd Nilius et al.   GENOME BIOLOGY

Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception

(2010) Kyeongjin Kang et al.   NATURE

Molecular basis of infrared detection by snakes

(2010) Elena O. Gracheva et al.   NATURE

A Gain-of-Function Mutation in TRPA1 Causes Familial Episodic Pain Syndrome

(2010) Barbara Kremeyer et al.   NEURON

Infrared Snake Eyes: TRPA1 and the Thermal Sensitivity of the Snake Pit Organ

(2010) V. C. Panzano et al.   Science Signaling

Anopheles gambiaeTRPA1 is a heat-activated channel expressed in thermosensitive sensilla of female antennae

(2009) Guirong Wang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The M34A mutant of Connexin26 reveals active conductance states in pore-suspending membranes

(2009) Oliver Gaßmann et al.   JOURNAL OF STRUCTURAL BIOLOGY

TRPA1 acts as a cold sensor in vitro and in vivo

(2009) Y. Karashima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Transmembrane Domain 5 as a Critical Molecular Determinant of Menthol Sensitivity in Mammalian TRPA1 Channels

(2008) B. Xiao et al.   JOURNAL OF NEUROSCIENCE

Rapid screening of membrane protein activity: electrophysiological analysis of OmpF reconstituted in proteoliposomes

(2008) Mohamed Kreir et al.   LAB ON A CHIP

An internal thermal sensor controlling temperature preference in Drosophila

(2008) Fumika N. Hamada et al.   NATURE

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY

High-resolution x-ray structure of human aquaporin 5

(2008) R. Horsefield et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The protein fluorescence and structural toolkit: Database and programs for the analysis of protein fluorescence and structural data

(2008) Chi Shen et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS