SopF, a phosphoinositide binding effector, promotes the stability of the nascent Salmonella-containing vacuole

Screening Mycobacterium tuberculosis Secreted Proteins Identifies Mpt64 as a Eukaryotic Membrane-Binding Bacterial Effector

(2019) Chelsea E. Stamm et al.   mSphere

The entry of Salmonella in a distinct tight compartment revealed at high temporal and ultrastructural resolution

(2018) Jennifer Fredlund et al.   CELLULAR MICROBIOLOGY

Quantitative Yeast Genetic Interaction Profiling of Bacterial Effector Proteins Uncovers a Role for the Human Retromer in Salmonella Infection

(2018) Kristin L. Patrick et al.   Cell Systems

Distinct roles for plasma membrane PtdIns(4)P and PtdIns(4,5)P 2 during receptor-mediated endocytosis in yeast

(2017) Wataru Yamamoto et al.   JOURNAL OF CELL SCIENCE

Identification of a NovelSalmonellaType III Effector by Quantitative Secretome Profiling

(2017) Sen Cheng et al.   MOLECULAR & CELLULAR PROTEOMICS

Functional relatedness in the Inv/Mxi-Spa type III secretion system family

(2017) Jessica A. Klein et al.   MOLECULAR MICROBIOLOGY

Combinatorial actions of bacterial effectors revealed by exploiting genetic tools in yeast

(2017) Alan Huett   Molecular Systems Biology

Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems

(2017) Eric M. Feeley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlled Activity of the Salmonella Invasion-Associated Injectisome Reveals Its Intracellular Role in the Cytosolic Population

(2017) Jessica A. Klein et al.   mBio

A systematic exploration of the interactions between bacterial effector proteins and host cell membranes

(2017) Bethany A. Weigele et al.   Nature Communications

A second wave of Salmonella T3SS1 activity prolongs the lifespan of infected epithelial cells

(2017) Ciaran E. Finn et al.   PLoS Pathogens

Swiss Army Pathogen: The Salmonella Entry Toolkit

(2017) Peter J. Hume et al.   Frontiers in Cellular and Infection Microbiology

SopB-Mediated Recruitment of SNX18 Facilitates Salmonella Typhimurium Internalization by the Host Cell

(2017) David Liebl et al.   Frontiers in Cellular and Infection Microbiology

The Salmonella effector SteA binds phosphatidylinositol 4-phosphate for subcellular targeting within host cells

(2016) Lia Domingues et al.   CELLULAR MICROBIOLOGY

Coxiella burnetiieffector CvpB modulates phosphoinositide metabolism for optimal vacuole development

(2016) Eric Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The type III secretion system apparatus determines the intracellular niche of bacterial pathogens

(2016) Juan Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping the Regulatory Network for Salmonella enterica Serovar Typhimurium Invasion

(2016) Carol Smith et al.   mBio

Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death

(2016) Teresa L. M. Thurston et al.   Nature Communications

The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium

(2016) Aoife M. Colgan et al.   PLoS Genetics

Macropinosomes are Key Players in Early Shigella Invasion and Vacuolar Escape in Epithelial Cells

(2016) Allon Weiner et al.   PLoS Pathogens

Autophagy Proteins Promote Repair of Endosomal Membranes Damaged by the Salmonella Type Three Secretion System 1

(2015) Saskia Kreibich et al.   Cell Host & Microbe

Dual 4- and 5-phosphatase activities regulate SopB-dependent phosphoinositide dynamics to promote bacterial entry

(2015) Heather L. Piscatelli et al.   CELLULAR MICROBIOLOGY

The COPII complex and lysosomal VAMP7 determine intracellularSalmonellalocalization and growth

(2015) José Carlos Santos et al.   CELLULAR MICROBIOLOGY

Legionella pneumophila Effector LpdA Is a Palmitoylated Phospholipase D Virulence Factor

(2015) Gunnar N. Schroeder et al.   INFECTION AND IMMUNITY

Host Cell-catalyzedS-Palmitoylation Mediates Golgi Targeting of theLegionellaUbiquitin Ligase GobX

(2015) Yi-Han Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Salmonellae interactions with host processes

(2015) Doris L. LaRock et al.   NATURE REVIEWS MICROBIOLOGY

Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome

(2015) Xi Luo et al.   PLoS Pathogens

Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens

(2014) Leigh A. Knodler et al.   Cell Host & Microbe

Shigella Subverts the Host Recycling Compartment to Rupture Its Vacuole

(2014) Nora Mellouk et al.   Cell Host & Microbe

TheSalmonella Typhimurium effector protein SopE transiently localizes to the early SCV and contributes to intracellular replication

(2014) Pascale Vonaesch et al.   CELLULAR MICROBIOLOGY

The Legionella longbeachae Icm/Dot Substrate SidC Selectively Binds Phosphatidylinositol 4-Phosphate with Nanomolar Affinity and Promotes Pathogen Vacuole-Endoplasmic Reticulum Interactions

(2014) Stephanie Dolinsky et al.   INFECTION AND IMMUNITY

A Novel Phosphatidylinositol 4,5-Bisphosphate Binding Domain Mediates Plasma Membrane Localization of ExoU and Other Patatin-like Phospholipases

(2014) Gregory H. Tyson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi

(2014) Gerald R.V. Hammond et al.   JOURNAL OF CELL BIOLOGY

The ubiquitin-like modifier FAT10 decorates autophagy-targeted Salmonella and contributes to Salmonella resistance in mice

(2014) V. Spinnenhirn et al.   JOURNAL OF CELL SCIENCE

Ena/VASP regulates mDia2-initiated filopodial length, dynamics, and function

(2014) Melanie Barzik et al.   MOLECULAR BIOLOGY OF THE CELL

Quantitative Assessment of Cytosolic Salmonella in Epithelial Cells

(2014) Leigh A. Knodler et al.   PLoS One

Golgi and plasma membrane pools of PI(4)P contribute to plasma membrane PI(4,5)P2 and maintenance of KCNQ2/3 ion channel current

(2014) E. J. Dickson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Machinery at Endoplasmic Reticulum-Plasma Membrane Contact Sites Contributes to Spatial Regulation of Multiple Legionella Effector Proteins

(2014) Andree Hubber et al.   PLoS Pathogens

Phosphatidylinositol 3,5-bisphosphate: Low abundance, high significance

(2013) Amber J. McCartney et al.   BIOESSAYS

The Legionella Effector RidL Inhibits Retrograde Trafficking to Promote Intracellular Replication

(2013) Ivo Finsel et al.   Cell Host & Microbe

The Annexin A2/p11 complex is required for efficient invasion ofSalmonella Typhimurium in epithelial cells

(2013) Carrie Jolly et al.   CELLULAR MICROBIOLOGY

LtpD Is a Novel Legionella pneumophila Effector That Binds Phosphatidylinositol 3-Phosphate and Inositol Monophosphatase IMPA1

(2013) Clare R. Harding et al.   INFECTION AND IMMUNITY

Exploitation of eukaryotic subcellular targeting mechanisms by bacterial effectors

(2013) Stuart W. Hicks et al.   NATURE REVIEWS MICROBIOLOGY

Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation

(2013) Tamas Balla   PHYSIOLOGICAL REVIEWS

Evolutionary Genomics of Salmonella enterica Subspecies

(2013) P. T. Desai et al.   mBio

Effectors of animal and plant pathogens use a common domain to bind host phosphoinositides

(2013) Dor Salomon et al.   Nature Communications

Comprehensive Assignment of Roles for Salmonella Typhimurium Genes in Intestinal Colonization of Food-Producing Animals

(2013) Roy R. Chaudhuri et al.   PLoS Genetics

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

The Bimodal Lifestyle of Intracellular Salmonella in Epithelial Cells: Replication in the Cytosol Obscures Defects in Vacuolar Replication

(2012) Preeti Malik-Kale et al.   PLoS One

The protein SdhA maintains the integrity of the Legionella-containing vacuole

(2012) E. A. Creasey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome sequencing reveals diversification of virulence factor content and possible host adaptation in distinct subpopulations of Salmonella enterica

(2011) Henk C den Bakker et al.   BMC GENOMICS

Subcellular Targeting of Salmonella Virulence Proteins by Host-Mediated S-Palmitoylation

(2011) Stuart W. Hicks et al.   Cell Host & Microbe

Coiled-coil domains enhance the membrane association of Salmonella type III effectors

(2011) Leigh A. Knodler et al.   CELLULAR MICROBIOLOGY

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

The Coxiella burnetii Dot/Icm System Delivers a Unique Repertoire of Type IV Effectors into Host Cells and Is Required for Intracellular Replication

(2011) Kimberly L. Carey et al.   PLoS Pathogens

The Phosphoinositide Phosphatase SopB Manipulates Membrane Surface Charge and Trafficking of the Salmonella-Containing Vacuole

(2010) Malina A. Bakowski et al.   Cell Host & Microbe

Sorting nexin 3 (SNX3) is a component of a tubular endosomal network induced by Salmonella and involved in maturation of the Salmonella-containing vacuole

(2010) Virginie Braun et al.   CELLULAR MICROBIOLOGY

So similar, yet so different: uncovering distinctive features in the genomes of Salmonella enterica serovars Typhimurium and Typhi

(2010) Sébastien C. Sabbagh et al.   FEMS MICROBIOLOGY LETTERS

Lipidation by the Host Prenyltransferase Machinery Facilitates Membrane Localization ofLegionella pneumophilaEffector Proteins

(2010) Stanimir S. Ivanov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissemination of invasiveSalmonellavia bacterial-induced extrusion of mucosal epithelia

(2010) Leigh A. Knodler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SKIP, the Host Target of the Salmonella Virulence Factor SifA, Promotes Kinesin-1-Dependent Vacuolar Membrane Exchanges

(2010) Audrey Dumont et al.   TRAFFIC

Legionella Metaeffector Exploits Host Proteasome to Temporally Regulate Cognate Effector

(2010) Tomoko Kubori et al.   PLoS Pathogens

The Virulence Protein SopD2 Regulates Membrane Dynamics of Salmonella-Containing Vacuoles

(2010) Nina Schroeder et al.   PLoS Pathogens

Diversification of a Salmonella Virulence Protein Function by Ubiquitin-Dependent Differential Localization

(2009) Jayesh C. Patel et al.   CELL

Ubiquitination of the bacterial inositol phosphatase, SopB, regulates its biological activity at the plasma membrane

(2009) Leigh A. Knodler et al.   CELLULAR MICROBIOLOGY

Galectin-3, a marker for vacuole lysis by invasive pathogens

(2009) Irit Paz et al.   CELLULAR MICROBIOLOGY

Salmonella takes control: effector-driven manipulation of the host

(2009) Emma J McGhie et al.   CURRENT OPINION IN MICROBIOLOGY

The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway

(2009) Y. T. Zheng et al.   JOURNAL OF IMMUNOLOGY

The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

(2009) Teresa L M Thurston et al.   NATURE IMMUNOLOGY

TheLegionella pneumophilaphosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole

(2008) Curdin Ragaz et al.   CELLULAR MICROBIOLOGY

The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth ofLegionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE

(2008) Stefan S. Weber et al.   CELLULAR MICROBIOLOGY

Rho Family GTPase Modification and Dependence on CAAXMotif-signaled Posttranslational Modification

(2008) Patrick J. Roberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab1 Guanine Nucleotide Exchange Factor SidM Is a Major Phosphatidylinositol 4-Phosphate-binding Effector Protein ofLegionella pneumophila

(2008) Eva Brombacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SopB promotes phosphatidylinositol 3-phosphate formation onSalmonellavacuoles by recruiting Rab5 and Vps34

(2008) Gustavo V. Mallo et al.   JOURNAL OF CELL BIOLOGY

Sorting nexin-1 defines an early phase of Salmonella-containing vacuole-remodeling during Salmonella infection

(2008) M. V. Bujny et al.   JOURNAL OF CELL SCIENCE

The Salmonella SPI-2 effector SseJ exhibits eukaryotic activator-dependent phospholipase A and glycerophospholipid : cholesterol acyltransferase activity

(2008) N. S. Lossi et al.   MICROBIOLOGY-SGM

Maintenance of Hormone-sensitive Phosphoinositide Pools in the Plasma Membrane Requires Phosphatidylinositol 4-Kinase IIIα

(2007) Andras Balla et al.   MOLECULAR BIOLOGY OF THE CELL