1H NMR-MS-based heterocovariance as a drug discovery tool for fishing bioactive compounds out of a complex mixture of structural analogues

Reconstruction of HMBC Correlation Networks: A Novel NMR-Based Contribution to Metabolite Mixture Analysis

(2018) Ali Bakiri et al.   Journal of Chemical Information and Modeling

Computer-Aided 13C NMR Chemical Profiling of Crude Natural Extracts without Fractionation

(2017) Ali Bakiri et al.   JOURNAL OF NATURAL PRODUCTS

Cytotoxic lanostane triterpenoids from the fruiting bodies of Piptoporus betulinus

(2017) Zeynep Tohtahon et al.   PHYTOCHEMISTRY

Could multivariate statistics exploit HPTLC and NMR data to reveal bioactive compounds? The case of Paeonia mascula

(2017) Vasiliki-Ioanna Boka et al.   Phytochemistry Letters

Integration of Molecular Networking and In-Silico MS/MS Fragmentation for Natural Products Dereplication

(2016) Pierre-Marie Allard et al.   ANALYTICAL CHEMISTRY

Extending accessible chemical space for the identification of novel leads

(2016) Jürgen Bajorath   Expert Opinion on Drug Discovery

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Statistical Correlations between HPLC Activity-Based Profiling Results and NMR/MS Microfraction Data to Deconvolute Bioactive Compounds in Mixtures

(2016) Samuel Bertrand et al.   MOLECULES

Heterocovariance Based Metabolomics as a Powerful Tool Accelerating Bioactive Natural Product Identification

(2016) Nektarios Aligiannis et al.   ChemistrySelect

The Regulation of Steroid Action by Sulfation and Desulfation

(2015) Jonathan W. Mueller et al.   ENDOCRINE REVIEWS

NMR-Based Metabolomic Study on Isatis tinctoria: Comparison of Different Accessions, Harvesting Dates, and the Effect of Repeated Harvesting

(2015) Niels Guldbrandsen et al.   JOURNAL OF NATURAL PRODUCTS

The re-emergence of natural products for drug discovery in the genomics era

(2015) Alan L. Harvey et al.   NATURE REVIEWS DRUG DISCOVERY

Accessing biological actions of Ganoderma secondary metabolites by in silico profiling

(2015) Ulrike Grienke et al.   PHYTOCHEMISTRY

Fungal strain matters: colony growth and bioactivity of the European medicinal polypores Fomes fomentarius, Fomitopsis pinicola and Piptoporus betulinus

(2015) Philipp Dresch et al.   AMB Express

Dereplication of depsides from the lichen Pseudevernia furfuracea by centrifugal partition chromatography combined to 13C nuclear magnetic resonance pattern recognition

(2014) Sarah K. Oettl et al.   ANALYTICA CHIMICA ACTA

2D NMR Barcoding and Differential Analysis of Complex Mixtures for Chemical Identification: The Actaea Triterpenes

(2014) Feng Qiu et al.   ANALYTICAL CHEMISTRY

Identification of Natural Metabolites in Mixture: A Pattern Recognition Strategy Based on 13C NMR

(2014) Jane Hubert et al.   ANALYTICAL CHEMISTRY

NMR Fingerprints of the Drug-like Natural-Product Space Identify Iotrochotazine A: A Chemical Probe to Study Parkinson’s Disease

(2014) Tanja Grkovic et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

European medicinal polypores – A modern view on traditional uses

(2014) Ulrike Grienke et al.   JOURNAL OF ETHNOPHARMACOLOGY

A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.

(2014) Qing Xia et al.   MOLECULES

Dereplication, Residual Complexity, and Rational Naming: The Case of the Actaea Triterpenes

(2012) Feng Qiu et al.   JOURNAL OF NATURAL PRODUCTS

Comprehensive Extraction Method Integrated with NMR Metabolomics: A New Bioactivity Screening Method for Plants, Adenosine A1 Receptor Binding Compounds inOrthosiphon stamineusBenth

(2011) Nancy Dewi Yuliana et al.   ANALYTICAL CHEMISTRY

Steroid sulfatase inhibitors for estrogen- and androgen-dependent cancers

(2011) Atul Purohit et al.   JOURNAL OF ENDOCRINOLOGY

Similar interactions of natural products with biosynthetic enzymes and therapeutic targets could explain why nature produces such a large proportion of existing drugs

(2011) Esther Kellenberger et al.   NATURAL PRODUCT REPORTS

Nuclear magnetic resonance and liquid chromatography–mass spectrometry combined with an incompleted separation strategy for identifying the natural products in crude extract

(2008) Dongmei Dai et al.   ANALYTICA CHIMICA ACTA