Statistical Correlations between HPLC Activity-Based Profiling Results and NMR/MS Microfraction Data to Deconvolute Bioactive Compounds in Mixtures

Normal phase HPLC-based activity profiling of non-polar crude plant extracts – acetylcholinesterase inhibiting guttiferones from Montrouziera cauliflora as a case study

(2016) Anne Landreau et al.   NATURAL PRODUCT RESEARCH

Current approaches and challenges for the metabolite profiling of complex natural extracts

(2015) Jean-Luc Wolfender et al.   JOURNAL OF CHROMATOGRAPHY A

Zebrafish Bioassay-Guided Microfractionation Identifies Anticonvulsant Steroid Glycosides from the Philippine Medicinal Plant Solanum torvum

(2014) Soura Challal et al.   ACS Chemical Neuroscience

Unambiguous Characterization of N-Glycans of Monoclonal Antibody Cetuximab by Integration of LC-MS/MS and 1H NMR Spectroscopy

(2014) Alena Wiegandt et al.   ANALYTICAL CHEMISTRY

The pharmaceutical industry and natural products: historical status and new trends

(2014) Bruno David et al.   PHYTOCHEMISTRY REVIEWS

Combined Use of Extract Libraries and HPLC-Based Activity Profiling for Lead Discovery: Potential, Challenges, and Practical Considerations

(2014) Olivier Potterat et al.   PLANTA MEDICA

Comprehensive profiling and marker identification in non-volatile citrus oil residues by mass spectrometry and nuclear magnetic resonance

(2013) Guillaume Marti et al.   FOOD CHEMISTRY

Targeting high-performance liquid chromatography–high-resolution mass spectrometry–solid-phase extraction–nuclear magnetic resonance analysis with high-resolution radical scavenging profiles—Bioactive secondary metabolites from the endophytic fungus Penicillium namyslowskii

(2013) Sileshi G. Wubshet et al.   JOURNAL OF CHROMATOGRAPHY A

Detection of metabolite induction in fungal co-cultures on solid media by high-throughput differential ultra-high pressure liquid chromatography–time-of-flight mass spectrometry fingerprinting

(2013) Samuel Bertrand et al.   JOURNAL OF CHROMATOGRAPHY A

De Novo Production of Metabolites by Fungal Co-culture of Trichophyton rubrum and Bionectria ochroleuca

(2013) Samuel Bertrand et al.   JOURNAL OF NATURAL PRODUCTS

High-Resolution MS, MS/MS, and UV Database of Fungal Secondary Metabolites as a Dereplication Protocol for Bioactive Natural Products

(2013) Tamam El-Elimat et al.   JOURNAL OF NATURAL PRODUCTS

Concepts and technologies for tracking bioactive compounds in natural product extracts: generation of libraries, and hyphenation of analytical processes with bioassays

(2013) Olivier Potterat et al.   NATURAL PRODUCT REPORTS

HPLC Profiling with At-line Microdilution Assay for the Early Identification of Anti-fungal Compounds in Plants from French Polynesia

(2013) Samuel Bertrand et al.   PHYTOCHEMICAL ANALYSIS

Cancer chemopreventive diterpenes from Salvia corrugata

(2013) Emanuela Giacomelli et al.   PHYTOCHEMISTRY

Metabolomics for the rapid dereplication of bioactive compounds from natural sources

(2013) Nancy Dewi Yuliana et al.   PHYTOCHEMISTRY REVIEWS

Integration of Microfractionation, qNMR and Zebrafish Screening for the In Vivo Bioassay-Guided Isolation and Quantitative Bioactivity Analysis of Natural Products

(2013) Nadine Bohni et al.   PLoS One

Resolving the problem of chromatographic overlap by 3D cross correlation (3DCC) processing of LC, MS and NMR data for characterization of complex glycan mixtures

(2012) Henning N. Behnken et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Unbiased evaluation of bioactive secondary metabolites in complex matrices

(2012) Taichi Inui et al.   FITOTERAPIA

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Coupling of a High-resolution Monoamine Oxidase-A Inhibitor Assay and HPLC-SPE-NMR for Advanced Bioactivity Profiling of Plant Extracts

(2012) Clara Grosso et al.   PHYTOCHEMICAL ANALYSIS

Acylated pregnane glycosides from Caralluma sinaica

(2012) Shaza M. Al-Massarani et al.   PHYTOCHEMISTRY

Dereplication of phytochemicals in plants by LC-ESI-MS and ESI-MSn

(2012) W.F. Smyth et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Confronting the Challenges of Natural Product-Based Antifungal Discovery

(2011) Terry Roemer et al.   CHEMISTRY & BIOLOGY

Clustered patterns of species origins of nature-derived drugs and clues for future bioprospecting

(2011) F. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advances in mass spectrometry-based post-column bioaffinity profiling of mixtures

(2010) Jeroen Kool et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data

(2010) Tomáš Pluskal et al.   BMC BIOINFORMATICS

Metabolomics for bioactivity assessment of natural products

(2010) Nancy Dewi Yuliana et al.   PHYTOTHERAPY RESEARCH

Novel Chemical Space Exploration via Natural Products

(2009) Josefin Rosén et al.   JOURNAL OF MEDICINAL CHEMISTRY

1H NMR and UPLC-MSEStatistical Heterospectroscopy: Characterization of Drug Metabolites (Xenometabolome) in Epidemiological Studies

(2008) Derek J. Crockford et al.   ANALYTICAL CHEMISTRY

Optimized liquid chromatography–mass spectrometry approach for the isolation of minor stress biomarkers in plant extracts and their identification by capillary nuclear magnetic resonance

(2008) Gaetan Glauser et al.   JOURNAL OF CHROMATOGRAPHY A

Method transfer for fast liquid chromatography in pharmaceutical analysis: Application to short columns packed with small particle. Part II: Gradient experiments

(2007) Davy Guillarme et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS