Hypoxia and mesenchymal stromal cells as key drivers of initial fracture healing in an equine in vitro fracture hematoma model
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Title
Hypoxia and mesenchymal stromal cells as key drivers of initial fracture healing in an equine in vitro fracture hematoma model
Authors
Keywords
Hypoxia, Bone fracture, Equines, Immune cells, Granulocytes, Horses, Blood, Cell differentiation
Journal
PLoS One
Volume 14, Issue 4, Pages e0214276
Publisher
Public Library of Science (PLoS)
Online
2019-04-05
DOI
10.1371/journal.pone.0214276
References
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Note: Only part of the references are listed.- Risk factors for race-day fatality in flat racing Thoroughbreds in Great Britain (2000 to 2013)
- (2018) Sarah M. Rosanowski et al. PLoS One
- A Pronounced Inflammatory Activity Characterizes the Early Fracture Healing Phase in Immunologically Restricted Patients
- (2017) Paula Hoff et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Use of locking compression plates in ulnar fractures of 18 horses*
- (2017) Carrie C. Jacobs et al. VETERINARY SURGERY
- Easy-to-use strategy for reference gene selection in quantitative real-time PCR experiments
- (2016) Stefanie Klenke et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Immunotolerant Properties of Mesenchymal Stem Cells: Updated Review
- (2016) Whitney Faiella et al. Stem Cells International
- Phenotypic switch of CD8+T cells reactivated under hypoxia toward IL-10 secreting, poorly proliferative effector cells
- (2015) Romain Vuillefroy de Silly et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Improved survival of mesenchymal stem cells by macrophage migration inhibitory factor
- (2015) Wenzheng Xia et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Fracture management in horses: Where have we been and where are we going?
- (2015) Jörg A. Auer et al. VETERINARY JOURNAL
- Interactions between MSCs and Immune Cells: Implications for Bone Healing
- (2015) Tracy K. Kovach et al. Journal of Immunology Research
- Comparative immunophenotyping of equine multipotent mesenchymal stromal cells: An approach toward a standardized definition
- (2014) Felicitas Paebst et al. CYTOMETRY PART A
- Metabolic requirements for the maintenance of self-renewing stem cells
- (2014) Keisuke Ito et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cell therapy for bone repair
- (2014) P. Rosset et al. Orthopaedics & Traumatology-Surgery & Research
- Suitable housekeeping genes for normalization of transcript abundance analysis by real-time RT-PCR in cultured bovine granulosa cells during hypoxia and differential cell plating density
- (2014) Vijay S Baddela et al. Reproductive Biology and Endocrinology
- Equine mesenchymal stem cells from bone marrow, adipose tissue and umbilical cord: immunophenotypic characterization and differentiation potential
- (2014) Danielle Barberini et al. Stem Cell Research & Therapy
- Characterization and osteogenic potential of equine muscle tissue– and periosteal tissue–derived mesenchymal stem cells in comparison with bone marrow– and adipose tissue–derived mesenchymal stem cells
- (2013) Catherine L. Radtke et al. AMERICAN JOURNAL OF VETERINARY RESEARCH
- Human immune cells' behavior and survival under bioenergetically restricted conditions in an in vitro fracture hematoma model
- (2013) Paula Hoff et al. Cellular & Molecular Immunology
- The influence of non-osteogenic factors on the expression of M-CSF and VEGF during fracture healing
- (2013) J. Köttstorfer et al. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
- How Vascular Endothelial Growth Factor-A (VEGF) Regulates Differentiation of Mesenchymal Stem Cells
- (2013) Agnes D. Berendsen et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Immunophenotypic, immunocytochemistry, ultrastructural, and cytogenetic characterization of mesenchymal stem cells from equine bone marrow
- (2013) Leandro Maia et al. MICROSCOPY RESEARCH AND TECHNIQUE
- Genomic responses in mouse models poorly mimic human inflammatory diseases
- (2013) Junhee Seok et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Terminally Differentiated CD8+ T Cells Negatively Affect Bone Regeneration in Humans
- (2013) S. Reinke et al. Science Translational Medicine
- Mesenchymal Stem Cells in Bone Regeneration
- (2013) M. Noelle Knight et al. Advances in Wound Care
- Effect of hypoxia on equine mesenchymal stem cells derived from bone marrow and adipose tissue
- (2012) Beatriz Ranera et al. BMC Veterinary Research
- Immunosuppressive Properties of Mesenchymal Stem Cells: Advances and Applications
- (2012) M. P. De Miguel et al. CURRENT MOLECULAR MEDICINE
- In search for cross-reactivity to immunophenotype equine mesenchymal stromal cells by multicolor flow cytometry
- (2012) Catharina De Schauwer et al. CYTOMETRY PART A
- Successful isolation of equine mesenchymal stromal cells from cryopreserved umbilical cord blood-derived mononuclear cell fractions
- (2012) C. De Schauwer et al. EQUINE VETERINARY JOURNAL
- Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation
- (2012) Yanqiu Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- Initial immune reaction and angiogenesis in bone healing
- (2012) Katharina Schmidt-Bleek et al. Journal of Tissue Engineering and Regenerative Medicine
- Hypoxia Promotes Osteogenesis but Suppresses Adipogenesis of Human Mesenchymal Stromal Cells in a Hypoxia-Inducible Factor-1 Dependent Manner
- (2012) Markus Wagegg et al. PLoS One
- Effects of a novel hydrogel on equine bone healing: A pilot study
- (2012) J. M. Cohen et al. VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY
- Osteoprogenitor Cell Therapy in an Equine Fracture Model
- (2012) Laurie A. McDuffee et al. VETERINARY SURGERY
- Endothelial Progenitor Cells (EPCs) and Mesenchymal Stem Cells (MSCs) in Bone Healing
- (2012) Nikolaos C. Keramaris et al. Current Stem Cell Research & Therapy
- Human Early Fracture Hematoma Is Characterized by Inflammation and Hypoxia
- (2011) Paula Kolar et al. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
- The biology of fracture healing
- (2011) Richard Marsell et al. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
- Local application of VEGF compensates callus deficiency after acute soft tissue trauma-results using a limb-shortening distraction procedure in rabbit tibia
- (2011) Sabine Ochman et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Mesenchymal stem cell effects on T-cell effector pathways
- (2011) Michelle M Duffy et al. Stem Cell Research & Therapy
- Fracture healing is accelerated in the absence of the adaptive immune system
- (2010) Daniel Toben et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Advances in the Establishment of Defined Mouse Models for the Study of Fracture Healing and Bone Regeneration
- (2010) J H Holstein et al. JOURNAL OF ORTHOPAEDIC TRAUMA
- VEGF Modulates Angiogenesis and Osteogenesis in Shockwave-Promoted Fracture Healing in Rabbits
- (2010) Ching-Jen Wang et al. JOURNAL OF SURGICAL RESEARCH
- Impaired fracture healing in macrophage migration inhibitory factor-deficient mice
- (2010) T. Kobayashi et al. OSTEOPOROSIS INTERNATIONAL
- Mechanisms underlying neutrophil-mediated monocyte recruitment
- (2009) O. Soehnlein et al. BLOOD
- Cellular composition of the initial fracture hematoma compared to a muscle hematoma: A study in sheep
- (2009) Katharina Schmidt-Bleek et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Characterization of α4β1 (CD49d/CD29) on equine leukocytes: Potential utility of a potent α4β1 (CD49d/CD29) receptor antagonist in the treatment of equine heaves (recurrent airway obstruction)
- (2009) Kelly M. Treonze et al. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
- Descriptive epidemiology of fractures occurring in British Thoroughbred racehorses in training
- (2007) K. L. P. Verheyen et al. EQUINE VETERINARY JOURNAL
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