Increases in miR-124-3p in Microglial Exosomes Confer Neuroprotective Effects by Targeting FIP200-Mediated Neuronal Autophagy Following Traumatic Brain Injury

miR-23b improves cognitive impairments in traumatic brain injury by targeting ATG12-mediated neuronal autophagy

(2018) Liqian Sun et al.   BEHAVIOURAL BRAIN RESEARCH

Exosomes from MiR-30d-5p-ADSCs Reverse Acute Ischemic Stroke-Induced, Autophagy-Mediated Brain Injury by Promoting M2 Microglial/Macrophage Polarization

(2018) Mei Jiang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Increased miR-124-3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons

(2018) Shan Huang et al.   FASEB JOURNAL

Increased miR-21-3p in injured brain microvascular endothelial cells following traumatic brain injury aggravates blood-brain barrier damage by promoting cellular apoptosis and inflammation through targeting MAT2B

(2018) Xintong Ge et al.   JOURNAL OF NEUROTRAUMA

Exosomes in Acquired Neurological Disorders: New Insights into Pathophysiology and Treatment

(2018) Nicole Osier et al.   MOLECULAR NEUROBIOLOGY

Cell-to-cell Communication by Extracellular Vesicles: Focus on Microglia

(2018) Rosa C. Paolicelli et al.   NEUROSCIENCE

miR-124-3p is a chronic regulator of gene expression after brain injury

(2018) Niina Vuokila et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A novel repetitive mild traumatic brain injury mouse model for chronic traumatic encephalopathy research

(2018) Xintong Ge et al.   JOURNAL OF NEUROSCIENCE METHODS

The Neuroprotective Role of MiR-124-3p in a 6-Hydroxydopamine-Induced Cell Model of Parkinson's Disease via the Regulation of ANAX5

(2017) Rui-Fang Dong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Traumatic brain injury: a global challenge

(2017) Walter D Johnson et al.   LANCET NEUROLOGY

Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research

(2017) Andrew I R Maas et al.   LANCET NEUROLOGY

Past, present and future of preserving and restoring function in the visual system: removing galectin-3 as a promising treatment

(2017) AnaM. Blanco Martinez et al.   Neural Regeneration Research

Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury

(2017) Yanlu Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Regulation of autophagy, NF-κB signaling, and cell viability by miR-124 in KRAS mutant mesenchymal-like NSCLC cells

(2017) Anita K. Mehta et al.   Science Signaling

Regulation of autophagy, NF-κB signaling, and cell viability by miR-124 in KRAS mutant mesenchymal-like NSCLC cells

(2017) Anita K. Mehta et al.   Science Signaling

MiRNA-124 induces neuroprotection and functional improvement after focal cerebral ischemia

(2016) Somayyeh Hamzei Taj et al.   BIOMATERIALS

miR-21-5p alleviates leakage of injured brain microvascular endothelial barrier in vitro through suppressing inflammation and apoptosis

(2016) Xintong Ge et al.   BRAIN RESEARCH

Extracellular vesicles: interneural shuttles of complex messages

(2016) Eva-Maria Krämer-Albers et al.   CURRENT OPINION IN NEUROBIOLOGY

Temporal Profile of MicroRNA Expression in Contused Cortex after Traumatic Brain Injury in Mice

(2016) Lilja Meissner et al.   JOURNAL OF NEUROTRAUMA

MiR-20a and miR-20b negatively regulate autophagy by targeting RB1CC1/FIP200 in breast cancer cells

(2016) Shufeng Li et al.   LIFE SCIENCES

Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons

(2016) Yi Zhang et al.   MOLECULAR NEUROBIOLOGY

Extracellular vesicles in neurodegenerative disease — pathogenesis to biomarkers

(2016) Alexander G. Thompson et al.   Nature Reviews Neurology

Extracellular vesicles round off communication in the nervous system

(2016) Vivian Budnik et al.   NATURE REVIEWS NEUROSCIENCE

Autophagy Biomarkers Beclin 1 and p62 are Increased in Cerebrospinal Fluid after Traumatic Brain Injury

(2016) Alicia K. Au et al.   Neurocritical Care

A novel cognitive impairment mechanism that astrocytic p-connexin 43 promotes neuronic autophagy via activation of P2X7R and down-regulation of GLT-1 expression in the hippocampus following traumatic brain injury in rats

(2015) Liqian Sun et al.   BEHAVIOURAL BRAIN RESEARCH

miR-21 alleviates secondary blood–brain barrier damage after traumatic brain injury in rats

(2015) Xintong Ge et al.   BRAIN RESEARCH

Establishment of Lipofection Protocol for Efficient miR-21 Transfection into Cortical NeuronsIn Vitro

(2015) Zhaoli Han et al.   DNA AND CELL BIOLOGY

Active endocannabinoids are secreted on extracellular membrane vesicles

(2015) M. Gabrielli et al.   EMBO REPORTS

MicroRNA-124 regulates glucocorticoid sensitivity by targeting phosphodiesterase 4B in diffuse large B cell lymphoma

(2015) Jinyoung Kim et al.   GENE

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

(2015) Hirohide Asai et al.   NATURE NEUROSCIENCE

Chromatographically isolated CD63+CD81+extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI

(2015) Dong-ki Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury

(2014) Chinmoy Sarkar et al.   Autophagy

miR-21 alleviated apoptosis of cortical neurons through promoting PTEN-Akt signaling pathway in vitro after experimental traumatic brain injury

(2014) Zhaoli Han et al.   BRAIN RESEARCH

Emerging Roles of Extracellular Vesicles in the Nervous System

(2014) L. Rajendran et al.   JOURNAL OF NEUROSCIENCE

Traumatic Brain Injury Dysregulates MicroRNAs to Modulate Cell Signaling in Rat Hippocampus

(2014) Liang Liu et al.   PLoS One

Resveratrol protects astrocytes against traumatic brain injury through inhibiting apoptotic and autophagic cell death

(2014) C-J Lin et al.   Cell Death & Disease

MiR-216a: a link between endothelial dysfunction and autophagy

(2014) R Menghini et al.   Cell Death & Disease

miR-21 improves the neurological outcome after traumatic brain injury in rats

(2014) Xin-Tong Ge et al.   Scientific Reports

MicroRNA-30b functions as a tumour suppressor in human colorectal cancer by targetingKRAS,PIK3CDandBCL2

(2013) Wen-Ting Liao et al.   JOURNAL OF PATHOLOGY

Autophagy Negatively Regulates Early Axon Growth in Cortical Neurons

(2013) B.-K. Ban et al.   MOLECULAR AND CELLULAR BIOLOGY

Animal models of traumatic brain injury

(2013) Ye Xiong et al.   NATURE REVIEWS NEUROSCIENCE

miR-210 suppresses BNIP3 to protect against the apoptosis of neural progenitor cells

(2013) Fei Wang et al.   Stem Cell Research

miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1

(2012) Gozde Korkmaz et al.   Autophagy

Wnt3a induces exosome secretion from primary cultured rat microglia

(2012) Claudie Hooper et al.   BMC NEUROSCIENCE

MicroRNA regulation of autophagy

(2012) L. B. Frankel et al.   CARCINOGENESIS

MiR-20a and miR-106b negatively regulate autophagy induced by leucine deprivation via suppression of ULK1 expression in C2C12 myoblasts

(2012) Hao Wu et al.   CELLULAR SIGNALLING

Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism

(2012) Flavia Antonucci et al.   EMBO JOURNAL

Head trauma in China

(2012) Ji-yao Jiang   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Chinese Head Trauma Data Bank: Effect of gender on the outcome of patients with severe traumatic brain injury

(2012) Guo-yi Gao et al.   JOURNAL OF NEUROTRAUMA

Traumatic brain injury: networks and neuropathology

(2012) Harvey Levin et al.   LANCET NEUROLOGY

miR-148b Functions as a Tumor Suppressor in Pancreatic Cancer by Targeting AMPK 1

(2012) G. Zhao et al.   MOLECULAR CANCER THERAPEUTICS

Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth

(2012) Hongqi Xin et al.   STEM CELLS

Downregulation of FIP200 Induces Apoptosis of Glioblastoma Cells and Microvascular Endothelial Cells by Enhancing Pyk2 Activity

(2011) Dongyan Wang et al.   PLoS One

MicroRNA-375 Is Downregulated in Gastric Carcinomas and Regulates Cell Survival by Targeting PDK1 and 14-3-3 

(2010) Y. Tsukamoto et al.   CANCER RESEARCH

Statins Promote the Degradation of Extracellular Amyloid β-Peptide by Microglia via Stimulation of Exosome-associated Insulin-degrading Enzyme (IDE) Secretion

(2010) Irfan Y. Tamboli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

(2010) Xuan Zhou et al.   LABORATORY INVESTIGATION

Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury

(2010) Dan Shlosberg et al.   Nature Reviews Neurology

Microarray based analysis of microRNA expression in rat cerebral cortex after traumatic brain injury

(2009) Ping Lei et al.   BRAIN RESEARCH

MicroRNAs Potentiate Neural Development

(2009) Sarah K. Fineberg et al.   NEURON

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL