Pleotropic Roles of Autotaxin in the Nervous System Present Opportunities for the Development of Novel Therapeutics for Neurological Diseases
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Title
Pleotropic Roles of Autotaxin in the Nervous System Present Opportunities for the Development of Novel Therapeutics for Neurological Diseases
Authors
Keywords
Autotaxin, Lysophospholipase D, Inflammatory neuropathic pain, Glioblastoma multiforme, Hemorrhagic hydrocephalus, Schizophrenia, Multiple sclerosis, Alzheimer’s disease, Metabolic syndrome-induced brain damage, Traumatic brain injury, Hepatic encephalopathy induced cerebral edema, Macular edema, Major depressive disorder, Stress-induced psychiatric disorder, Alcohol-induced brain damage, HIV-induced brain injury, Pruritus, Peripheral nerve injury
Journal
MOLECULAR NEUROBIOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-30
DOI
10.1007/s12035-019-01719-1
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Note: Only part of the references are listed.- Lysophosphatidic acid activates satellite glia cells and Schwann cells
- (2019) Jan W. Robering et al. GLIA
- Reduced Serum and Cerebrospinal Fluid Levels of Autotaxin in Major Depressive Disorder
- (2019) Kei Itagaki et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Potential Therapeutic Applications for Inhibitors of Autotaxin, a Bioactive Lipid-Producing Lysophospholipase D, in Disorders Affecting the Nervous System
- (2018) Deron R. Herr et al. ACS Chemical Neuroscience
- Lysophosphatidic acid receptor, LPA 6 , regulates endothelial blood-brain barrier function: Implication for hepatic encephalopathy
- (2018) Kayo Masago et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cellular origin of glioblastoma and its implication in precision therapy
- (2018) Maojin Yao et al. Cellular & Molecular Immunology
- Autotaxin–Lysophosphatidic Acid Signaling in Alzheimer’s Disease
- (2018) Sindhu Ramesh et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders
- (2018) Carine Thalman et al. MOLECULAR PSYCHIATRY
- Safety, tolerability, pharmacokinetics, and pharmacodynamics of GLPG1690, a novel autotaxin inhibitor, to treat idiopathic pulmonary fibrosis (FLORA): a phase 2a randomised placebo-controlled trial
- (2018) Toby M Maher et al. Lancet Respiratory Medicine
- Lysophosphatidic acid and its receptor LPA1 mediate carrageenan induced inflammatory pain in mice
- (2018) Malavika Srikanth et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study
- (2018) Ken Kuwajima et al. PLoS One
- ANNALS EXPRESS: Autotaxin and sIL-2R levels in cerebrospinal fluids are useful for the diagnosis of central nervous system invasion caused by hematological malignancies
- (2018) Takuya Shimura et al. ANNALS OF CLINICAL BIOCHEMISTRY
- Lysophosphatidic Acid Protects Against Endotoxin-Induced Acute Kidney Injury
- (2017) Koryun Mirzoyan et al. INFLAMMATION
- Autotaxin is Related to Metabolic Dysfunction and Predicts Alzheimer’s Disease Outcomes
- (2017) Kelsey E. McLimans et al. JOURNAL OF ALZHEIMERS DISEASE
- Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis
- (2017) Nicolas Desroy et al. JOURNAL OF MEDICINAL CHEMISTRY
- Blocking lysophosphatidic acid receptor 1 signaling inhibits diabetic nephropathy in db/db mice
- (2017) Hui Ying Li et al. KIDNEY INTERNATIONAL
- Lysophosphatidic acid receptors (LPARs): Potential targets for the treatment of neuropathic pain
- (2017) María Velasco et al. NEUROPHARMACOLOGY
- Identification and pharmacological characterization of a novel inhibitor of autotaxin in rodent models of joint pain
- (2017) K. Thirunavukkarasu et al. OSTEOARTHRITIS AND CARTILAGE
- Dysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis
- (2017) K. Schmitz et al. Acta Neuropathologica Communications
- Genome-wide analysis identifies colonic genes differentially associated with serum leptin and insulin concentrations in C57BL/6J mice fed a high-fat diet
- (2017) Sung-Eun Kim et al. PLoS One
- HIV-1 Tat Inhibits Autotaxin Lysophospholipase D Activity and Modulates Oligodendrocyte Differentiation
- (2016) Natalie A. Wheeler et al. ASN Neuro
- Development of Autotaxin Inhibitors: An Overview of the Patent and Primary Literature
- (2016) Diana Castagna et al. JOURNAL OF MEDICINAL CHEMISTRY
- Secret talk between adipose tissue and central nervous system via secreted factors—an emerging frontier in the neurodegenerative research
- (2016) Avinash Parimisetty et al. Journal of Neuroinflammation
- Fingolimod promotes peripheral nerve regeneration via modulation of lysophospholipid signaling
- (2016) Fabian Szepanowski et al. Journal of Neuroinflammation
- Serum Autotaxin Activity Correlates With Pruritus in Pediatric Cholestatic Disorders
- (2016) Andreas E. Kremer et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Myelin-related gene silencing mediated by LPA1 – Rho/ROCK signaling is correlated to acetylation of NFκB in S16 Schwann cells
- (2016) Ryoko Tsukahara et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Structural basis for specific inhibition of Autotaxin by a DNA aptamer
- (2016) Kazuki Kato et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- To fingolimod and beyond: The rich pipeline of drug candidates that target S1P signaling
- (2016) Wee Siong Chew et al. PHARMACOLOGICAL RESEARCH
- LYSOPHOSPHATIDIC ACIDS AND AUTOTAXIN IN RETINAL VEIN OCCLUSION
- (2016) Ivanka Dacheva et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design
- (2016) Spencer B. Jones et al. ACS Medicinal Chemistry Letters
- Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus
- (2016) Raehee Park et al. Nature Communications
- Structural basis for specific inhibition of Autotaxin by a DNA aptamer
- (2016) Kazuki Kato et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Lysophosphatidic acid and signaling in sensory neurons
- (2015) Ronald P.J. Oude Elferink et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Autotaxin Derived From Lipoprotein(a) and Valve Interstitial Cells Promotes Inflammation and Mineralization of the Aortic ValveCLINICAL PERSPECTIVE
- (2015) Rihab Bouchareb et al. CIRCULATION
- Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP
- (2015) J. Vogt et al. EMBO Molecular Medicine
- Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer
- (2015) Matthew G K Benesch et al. ENDOCRINE-RELATED CANCER
- New insights into the autotaxin/LPA axis in cancer development and metastasis
- (2015) Raphaël Leblanc et al. EXPERIMENTAL CELL RESEARCH
- Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: implications for cancer treatment
- (2015) Ganesh Venkatraman et al. FASEB JOURNAL
- Tumor-induced inflammation in mammary adipose tissue stimulates a vicious cycle of autotaxin expression and breast cancer progression
- (2015) Matthew G. K. Benesch et al. FASEB JOURNAL
- Lysophosphatidic acid receptors LPA4and LPA6differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes
- (2015) Erina Hata et al. INTERNATIONAL IMMUNOLOGY
- Autotaxin activity has a high accuracy to diagnose intrahepatic cholestasis of pregnancy
- (2015) Andreas E. Kremer et al. JOURNAL OF HEPATOLOGY
- Definition of a Novel Pathway Centered on Lysophosphatidic Acid To Recruit Monocytes during the Resolution Phase of Tissue Inflammation
- (2015) Simon McArthur et al. JOURNAL OF IMMUNOLOGY
- Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis
- (2015) Mohamad Navab et al. JOURNAL OF LIPID RESEARCH
- The Autotaxin-Lysophosphatidic Acid Axis Modulates Histone Acetylation and Gene Expression during Oligodendrocyte Differentiation
- (2015) N. A. Wheeler et al. JOURNAL OF NEUROSCIENCE
- The autotaxin-lysophosphatidic acid–lysophosphatidic acid receptor cascade: proposal of a novel potential therapeutic target for treating glioblastoma multiforme
- (2015) Sadaharu Tabuchi Lipids in Health and Disease
- Serum Autotaxin/ENPP2 correlates with insulin resistance in older humans with obesity
- (2015) Valerie L. Reeves et al. Obesity
- Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics
- (2015) Joanna M. Woodcock et al. Oncotarget
- LPA signaling initiates schizophrenia-like brain and behavioral changes in a mouse model of prenatal brain hemorrhage
- (2015) H Mirendil et al. Translational Psychiatry
- Non-cell autonomous and non-catalytic activities of ATX in the developing brain
- (2015) Raanan Greenman et al. Frontiers in Neuroscience
- Autotaxin Overexpression Causes Embryonic Lethality and Vascular Defects
- (2015) Hiroshi Yukiura et al. PLoS One
- Autotaxin and Endotoxin-Induced Acute Lung Injury
- (2015) Marios-Angelos Mouratis et al. PLoS One
- The Bulk of Autotaxin Activity Is Dispensable for Adult Mouse Life
- (2015) Aggeliki Katsifa et al. PLoS One
- Exon Microarray Analysis of Human Dorsolateral Prefrontal Cortex in Alcoholism
- (2014) Ann M. Manzardo et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Potentials of the Circulating Pruritogenic Mediator Lysophosphatidic Acid in Development of Allergic Skin Inflammation in Mice
- (2014) Yoshibumi Shimizu et al. AMERICAN JOURNAL OF PATHOLOGY
- Loss of lysophosphatidic acid receptor LPA1 alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex
- (2014) Beatriz García-Díaz et al. Brain Structure & Function
- ENPP2 Contributes to Adipose Tissue Expansion and Insulin Resistance in Diet-Induced Obesity
- (2014) S. Nishimura et al. DIABETES
- Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice
- (2014) Matthew G. K. Benesch et al. FASEB JOURNAL
- Autotaxin in the crosshairs: Taking aim at cancer and other inflammatory conditions
- (2014) Matthew G.K. Benesch et al. FEBS LETTERS
- Role of p38MAPK in S1P receptor-mediated differentiation of human oligodendrocyte progenitors
- (2014) Qiao Ling Cui et al. GLIA
- Autotaxin Downregulates LPS-Induced Microglia Activation and Pro-Inflammatory Cytokines Production
- (2014) Rana Awada et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Complexities of lysophospholipid signalling in glioblastoma
- (2014) Wayne Ng et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Autotaxin Produced by Stromal Cells Promotes LFA-1–Independent and Rho-Dependent Interstitial T Cell Motility in the Lymph Node Paracortex
- (2014) Tomoya Katakai et al. JOURNAL OF IMMUNOLOGY
- Serum Autotaxin Levels Correlate with Pruritus in Patients with Atopic Dermatitis
- (2014) Momoko Nakao et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- LPA receptor signaling: pharmacology, physiology, and pathophysiology
- (2014) Yun C. Yung et al. JOURNAL OF LIPID RESEARCH
- Increased autotaxin activity in multiple sclerosis
- (2014) Hamid Zahednasab et al. JOURNAL OF NEUROIMMUNOLOGY
- Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes
- (2014) Peter J Crack et al. Journal of Neuroinflammation
- Pericytes prevent regression of endothelial cell tubes by accelerating metabolism of lysophosphatidic acid
- (2014) Rūta Motiejūnaitė et al. MICROVASCULAR RESEARCH
- A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation In Vivo and Regulates Urethral Tension
- (2014) Hiroshi Saga et al. PLoS One
- Autotaxin Production of Lysophosphatidic Acid Mediates Allergic Asthmatic Inflammation
- (2013) Gye Young Park et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- PF-8380 and Closely Related Analogs: Synthesis and Structure-Activity Relationship towards Autotaxin Inhibition and Glioma Cell Viability
- (2013) Patrick-Denis St-Cœur et al. ARCHIV DER PHARMAZIE
- Over-expression of the miRNA cluster at chromosome 14q32 in the alcoholic brain correlates with suppression of predicted target mRNA required for oligodendrocyte proliferation
- (2013) A.M. Manzardo et al. GENE
- Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice
- (2013) Abdel K. Salous et al. JOURNAL OF LIPID RESEARCH
- Intraventricular Hemorrhage and Neurodevelopmental Outcomes in Extreme Preterm Infants
- (2013) Srinivas Bolisetty et al. PEDIATRICS
- Autotaxin Inhibition with PF-8380 Enhances the Radiosensitivity of Human and Murine Glioblastoma Cell Lines
- (2013) Sandeep R. Bhave et al. Frontiers in Oncology
- Blockage of Lysophosphatidic Acid Signaling Improves Spinal Cord Injury Outcomes
- (2012) Yona Goldshmit et al. AMERICAN JOURNAL OF PATHOLOGY
- Role of the autotaxin–lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy
- (2012) David N. Brindley et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Lysophospholipids and their receptors in the central nervous system
- (2012) Ji Woong Choi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Autotaxin in embryonic development
- (2012) Wouter H. Moolenaar et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Lysophosphatidic acid: Chemical signature of neuropathic pain
- (2012) Hiroshi Ueda et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Lysophosphatidic acid induces increased BACE1 expression and Aβ formation
- (2012) Jing Shi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- ATX and LPA receptor 3 are coordinately up-regulated in lipopolysaccharide-stimulated THP-1 cells through PKR and SPK1-mediated pathways
- (2012) Song Li et al. FEBS LETTERS
- 11-deoxy prostaglandin F2α, a thromboxane A2 receptor agonist, partially alleviates embryo crowding in Lpar3(−/−) females
- (2012) Xiaoqin Ye et al. FERTILITY AND STERILITY
- Autotaxin/ENPP2 regulates oligodendrocyte differentiation in vivo in the developing zebrafish hindbrain
- (2012) Larra W. Yuelling et al. GLIA
- Serum autotaxin is increased in pruritus of cholestasis, but not of other origin, and responds to therapeutic interventions
- (2012) Andreas E. Kremer et al. HEPATOLOGY
- Targeted Deletion of LPA5Identifies Novel Roles for Lysophosphatidic Acid Signaling in Development of Neuropathic Pain
- (2012) Mu-En Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autotaxin and Its Product Lysophosphatidic Acid Suppress Brown Adipose Differentiation and Promote Diet-Induced Obesity in Mice
- (2012) Lorenzo Federico et al. MOLECULAR ENDOCRINOLOGY
- Autotaxin-Lysophosphatidic Acid Axis Is a Novel Molecular Target for Lowering Intraocular Pressure
- (2012) Padma Iyer et al. PLoS One
- Autotaxin and LPA receptor signaling in cancer
- (2011) Anna J. S. Houben et al. CANCER AND METASTASIS REVIEWS
- Modulation of LPA Receptor Expression in the Human Brain Following Neurotrauma
- (2011) Tony Frugier et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Benzyl and Naphthalene Methylphosphonic Acid Inhibitors of Autotaxin with Anti-invasive and Anti-metastatic Activity
- (2011) Renuka Gupte et al. ChemMedChem
- Mediators of pruritus during cholestasis
- (2011) Ronald PJ Oude Elferink et al. CURRENT OPINION IN GASTROENTEROLOGY
- Autotaxin is required for the cranial neural tube closure and establishment of the midbrain-hindbrain boundary during mouse development
- (2011) Seiichi Koike et al. DEVELOPMENTAL DYNAMICS
- Unique uterine localization and regulation may differentiate LPA3 from other lysophospholipid receptors for its role in embryo implantation
- (2011) Xiaoqin Ye et al. FERTILITY AND STERILITY
- Autotaxin protects microglial cells against oxidative stress
- (2011) Rana Awada et al. FREE RADICAL BIOLOGY AND MEDICINE
- Binding of Autotaxin to Integrins Localizes Lysophosphatidic Acid Production to Platelets and Mammalian Cells
- (2011) Zachary Fulkerson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure-Based Design of Novel Boronic Acid-Based Inhibitors of Autotaxin
- (2011) Harald M. H. G. Albers et al. JOURNAL OF MEDICINAL CHEMISTRY
- Pre-emptive morphine treatment abolishes nerve injury-induced lysophospholipid synthesis in mass spectrometrical analysis
- (2011) Jun Nagai et al. JOURNAL OF NEUROCHEMISTRY
- Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosis
- (2011) Song Li et al. Molecular Cancer
- Antinociceptive Effect of Cyclic Phosphatidic Acid and Its Derivative on Animal Models of Acute and Chronic Pain
- (2011) Yasutaka Kakiuchi et al. Molecular Pain
- Structural basis of substrate discrimination and integrin binding by autotaxin
- (2011) Jens Hausmann et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Autotaxin and LPA Receptors Represent Potential Molecular Targets for the Radiosensitization of Murine Glioma through Effects on Tumor Vasculature
- (2011) Stephen M. Schleicher et al. PLoS One
- Stereotyped fetal brain disorganization is induced by hypoxia and requires lysophosphatidic acid receptor 1 (LPA1) signaling
- (2011) K. J. Herr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lysophosphatidic Acid Signaling May Initiate Fetal Hydrocephalus
- (2011) Y. C. Yung et al. Science Translational Medicine
- LPA Receptors: Subtypes and Biological Actions
- (2010) Ji Woong Choi et al. Annual Review of Pharmacology and Toxicology
- A novel, orally active LPA1 receptor antagonist inhibits lung fibrosis in the mouse bleomycin model
- (2010) JS Swaney et al. BRITISH JOURNAL OF PHARMACOLOGY
- A novel mutation in LPAR6 causes autosomal recessive hypotrichosis of the scalp
- (2010) S. Nahum et al. CLINICAL AND EXPERIMENTAL DERMATOLOGY
- ATX expression and LPA signalling are vital for the development of the nervous system
- (2010) Stella Fotopoulou et al. DEVELOPMENTAL BIOLOGY
- Lysophosphatidic Acid Is a Potential Mediator of Cholestatic Pruritus
- (2010) Andreas E. Kremer et al. GASTROENTEROLOGY
- PrevalentLIPHfounder mutations lead to loss of P2Y5 activation ability of PA-PLA1α in autosomal recessive hypotrichosis
- (2010) Satoru Shinkuma et al. HUMAN MUTATION
- Lipidomics reveals a remarkable diversity of lipids in human plasma,
- (2010) Oswald Quehenberger et al. JOURNAL OF LIPID RESEARCH
- Evidence for De Novo Synthesis of Lysophosphatidic Acid in the Spinal Cord through Phospholipase A2 and Autotaxin in Nerve Injury-Induced Neuropathic Pain
- (2010) L. Ma et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Phospholipase C Activation Drives Increased Production of Autotaxin in Endothelial Cells and Lysophosphatidic Acid-Dependent Regression
- (2010) E. Im et al. MOLECULAR AND CELLULAR BIOLOGY
- Autotaxin expression and its connection with the TNF-alpha-NF-κB axis in human hepatocellular carcinoma
- (2010) Jian-Min Wu et al. Molecular Cancer
- Autotaxin Signaling via Lysophosphatidic Acid Receptors Contributes to Vascular Endothelial Growth Factor-Induced Endothelial Cell Migration
- (2010) M. M. Ptaszynska et al. MOLECULAR CANCER RESEARCH
- Autotaxin and Lysophosphatidic Acid1 receptor-Mediated Demyelination of Dorsal Root Fibers by Sciatic Nerve Injury and Intrathecal Lysophosphatidylcholine
- (2010) Jun Nagai et al. Molecular Pain
- Direct profiling of phospholipids and lysophospholipids in rat brain sections after ischemic stroke
- (2010) Hay-Yan J. Wang et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases
- (2009) Shuying Liu et al. CANCER CELL
- Modulation of invasive properties of CD133(+) glioblastoma stem cells: A role for MT1-MMP in bioactive lysophospholipid signaling
- (2009) Borhane Annabi et al. MOLECULAR CARCINOGENESIS
- Lysophosphatidic Acid-3 Receptor-Mediated Feed-Forward Production of Lysophosphatidic Acid: an Initiator of Nerve Injury-Induced Neuropathic Pain
- (2009) Lin Ma et al. Molecular Pain
- Lysophosphatidic acid (LPA) receptors: Signaling properties and disease relevance
- (2009) Mu-En Lin et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Involvement of the Lysophosphatidic Acid-Generating Enzyme Autotaxin in Lymphocyte-Endothelial Cell Interactions
- (2008) Tae Nakasaki et al. AMERICAN JOURNAL OF PATHOLOGY
- Lipopolysaccharide induces autotaxin expression in human monocytic THP-1 cells
- (2008) Song Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Autotaxin (ATX): A multi-functional and multi-modular protein possessing enzymatic lysoPLD activity and matricellular properties
- (2008) L YUELLING BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Anticancer activity of FTY720: Phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D
- (2008) Laurens A. van Meeteren et al. CANCER LETTERS
- Autosomal recessive woolly hair with hypotrichosis caused by a novel homozygous mutation in theP2RY5gene
- (2008) Yutaka Shimomura et al. EXPERIMENTAL DERMATOLOGY
- Lysophosphatidic Acid Receptor-dependent Secondary Effects via Astrocytes Promote Neuronal Differentiation
- (2008) Tânia Cristina de Sampaio e Spohr et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX-mediated conversion to LPA, an initiator of neuropathic pain
- (2008) Makoto Inoue et al. JOURNAL OF NEUROCHEMISTRY
- S32826, A Nanomolar Inhibitor of Autotaxin: Discovery, Synthesis and Applications as a Pharmacological Tool
- (2008) G. Ferry et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Role of LPA4/p2y9/GPR23 in Negative Regulation of Cell Motility
- (2008) Zendra Lee et al. MOLECULAR BIOLOGY OF THE CELL
- Autotaxin, a Synthetic Enzyme of Lysophosphatidic Acid (LPA), Mediates the Induction of Nerve-Injured Neuropathic Pain
- (2008) Makoto Inoue et al. Molecular Pain
- G protein–coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth
- (2008) Sandra M Pasternack et al. NATURE GENETICS
- Lysophosphatidic Acid can Support the Formation of Membranous Structures and an Increase in MBP mRNA Levels in Differentiating Oligodendrocytes
- (2008) Luciana Nogaroli et al. NEUROCHEMICAL RESEARCH
- Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid
- (2008) M. Inoue et al. NEUROSCIENCE
- Phosphodiesterase-Iα/autotaxin's MORFO domain regulates oligodendroglial process network formation and focal adhesion organization
- (2007) Jameel Dennis et al. MOLECULAR AND CELLULAR NEUROSCIENCE
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