The autotaxin-lysophosphatidic acid–lysophosphatidic acid receptor cascade: proposal of a novel potential therapeutic target for treating glioblastoma multiforme

Promising Pharmacological Directions in the World of Lysophosphatidic Acid Signaling

(2015) Nicole C. Stoddard et al.   Biomolecules & Therapeutics

Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice

(2014) Matthew G. K. Benesch et al.   FASEB JOURNAL

Design of anticancer lysophosphatidic acid agonists and antagonists

(2014) Abby L Parrill   Future Medicinal Chemistry

Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes

(2014) Peter J Crack et al.   Journal of Neuroinflammation

A comparison of long-term survivors and short-term survivors with glioblastoma, subventricular zone involvement: a predictive factor for survival?

(2014) Sebastian Adeberg et al.   Radiation Oncology

Lysophosphatidic acid promotes secretion of VEGF by increasing expression of 150-kD Oxygen-regulated protein (ORP150) in mesenchymal stem cells

(2013) Hua Wei et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Autotaxin inhibitors: a patent review

(2013) Efrosini Barbayianni et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Autotaxin Inhibition with PF-8380 Enhances the Radiosensitivity of Human and Murine Glioblastoma Cell Lines

(2013) Sandeep R. Bhave et al.   Frontiers in Oncology

Lysophospholipids and their receptors in the central nervous system

(2012) Ji Woong Choi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lysophosphatidic acid induces increased BACE1 expression and Aβ formation

(2012) Jing Shi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo

(2012) Mayumi Komachi et al.   CANCER SCIENCE

Bevacizumab for the treatment of high-grade glioma

(2012) Mustafa Khasraw et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Relationship of glioblastoma multiforme to the subventricular zone is associated with survival

(2012) Nazia F. Jafri et al.   NEURO-ONCOLOGY

Autotaxin and LPA receptor signaling in cancer

(2011) Anna J. S. Houben et al.   CANCER AND METASTASIS REVIEWS

Modulation of LPA Receptor Expression in the Human Brain Following Neurotrauma

(2011) Tony Frugier et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

(2011) Hiroshi Nishimasu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Autotaxin and LPA Receptors Represent Potential Molecular Targets for the Radiosensitization of Murine Glioma through Effects on Tumor Vasculature

(2011) Stephen M. Schleicher et al.   PLoS One

Lysophosphatidic acid production and action: critical new players in breast cancer initiation and progression

(2010) N Panupinthu et al.   BRITISH JOURNAL OF CANCER

LPA receptor expression in the central nervous system in health and following injury

(2010) Yona Goldshmit et al.   CELL AND TISSUE RESEARCH

ATX-LPA receptor axis in inflammation and cancer

(2010) Shuying Liu et al.   CELL CYCLE

International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature

(2010) J. Chun et al.   PHARMACOLOGICAL REVIEWS

Dual Activity Lysophosphatidic Acid Receptor Pan-Antagonist/Autotaxin Inhibitor Reduces Breast Cancer Cell Migration In vitro and Causes Tumor Regression In vivo

(2009) Honglu Zhang et al.   CANCER RESEARCH

Autotaxin/Lysopholipase D and Lysophosphatidic Acid Regulate Murine Hemostasis and Thrombosis

(2009) Zehra Pamuklar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Modulation of invasive properties of CD133(+) glioblastoma stem cells: A role for MT1-MMP in bioactive lysophospholipid signaling

(2009) Borhane Annabi et al.   MOLECULAR CARCINOGENESIS

Antiangiogenic therapies for high-grade glioma

(2009) Andrew D. Norden et al.   Nature Reviews Neurology

Cerebral Ischemia Promotes Rich Pseudopalisading Necrosis in the Rat C6 Glioblastoma Model

(2009) Mahabub H. MAMUN et al.   NEUROLOGIA MEDICO-CHIRURGICA

Human neural progenitors express functional lysophospholipid receptors that regulate cell growth and morphology

(2008) Jillian H Hurst et al.   BMC NEUROSCIENCE

Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma

(2008) Akiko Masuda et al.   BRITISH JOURNAL OF HAEMATOLOGY

Therapeutic Potential of Autotaxin/Lysophospholipase D Inhibitors

(2008) Lorenzo Federico et al.   CURRENT DRUG TARGETS

Relationship of glioblastoma multiforme to the lateral ventricles predicts survival following tumor resection

(2008) Kaisorn L. Chaichana et al.   JOURNAL OF NEURO-ONCOLOGY

Role of LPA4/p2y9/GPR23 in Negative Regulation of Cell Motility

(2008) Zendra Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Influence of acetylsalicylate on plasma lysophosphatidic acid level in patients with ischemic cerebral vascular diseases

(2008) Zhen-Guang Li et al.   NEUROLOGICAL RESEARCH

Lysophosphatidic Acid Inhibits Neuronal Differentiation of Neural Stem/Progenitor Cells Derived from Human Embryonic Stem Cells

(2008) Mirella Dottori et al.   STEM CELLS