Advances in genetics of migraine

Novel hypotheses emerging from GWAS in migraine?

(2019) Arn M. J. M. van den Maagdenberg et al.   JOURNAL OF HEADACHE AND PAIN

Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations

(2019) Fabiola P. Monteiro et al.   European Journal of Medical Genetics

ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder

(2019) Lloyd B. Williams et al.   GENETICS IN MEDICINE

Genome-wide DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine

(2018) Zachary F. Gerring et al.   BMC GENOMICS

PRRT2 controls neuronal excitability by negatively modulating Na+ channel 1.2/1.6 activity

(2018) Floriana Fruscione et al.   BRAIN

Migraine and associated comorbidities are three times more frequent in children with ADHD and their mothers

(2018) Meryem Ozlem Kutuk et al.   BRAIN & DEVELOPMENT

Regulatory variants: from detection to predicting impact

(2018) Elena Rojano et al.   BRIEFINGS IN BIOINFORMATICS

Localization of migraine susceptibility genes in human brain by single-cell RNA sequencing

(2018) William Renthal   CEPHALALGIA

The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: A clinical and genetic study in Finnish migraine families

(2018) Marjo Eveliina Hiekkala et al.   CEPHALALGIA

Gain of function of sporadic/familial hemiplegic migraine-causing SCN1A mutations: Use of an optimized cDNA

(2018) Sara Bertelli et al.   CEPHALALGIA

Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition

(2018)   CEPHALALGIA

Phenotypes, genotypes, and the management of paroxysmal movement disorders

(2018) Laura Silveira-Moriyama et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Molecular genetic overlap between migraine and major depressive disorder

(2018) Yuanhao Yang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A Phase-by-Phase Review of Migraine Pathophysiology

(2018) David W. Dodick   HEADACHE

The NRP1 migraine risk variant shows evidence of association with menstrual migraine

(2018) Charmaine E. Pollock et al.   JOURNAL OF HEADACHE AND PAIN

Polygenic risk score: use in migraine research

(2018) Mona Ameri Chalmer et al.   JOURNAL OF HEADACHE AND PAIN

Clinical spectrum of hemiplegic migraine and chances of finding a pathogenic mutation

(2018) Nadine Pelzer et al.   NEUROLOGY

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

(2018) Padhraig Gormley et al.   NEURON

Pathophysiological mechanisms of migraine and epilepsy: Similarities and differences

(2018) Massimo Mantegazza et al.   NEUROSCIENCE LETTERS

Gain of Function for the SCN1A/hNav1.1-L1670W Mutation Responsible for Familial Hemiplegic Migraine

(2018) Sandra Dhifallah et al.   Frontiers in Molecular Neuroscience

A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N = 223,773)

(2018) Weihua Meng et al.   EBioMedicine

Major intra-familial phenotypic heterogeneity and incomplete penetrance due to a CACNA1A pathogenic variant

(2018) Chloé Angelini et al.   European Journal of Medical Genetics

Using a Genetic Risk Score Approach to Predict Headache Response to Triptans in Migraine Without Aura

(2018) Sarah Cargnin et al.   JOURNAL OF CLINICAL PHARMACOLOGY

New CACNA1A deletions are associated to migraine phenotypes

(2018) G. S. Grieco et al.   JOURNAL OF HEADACHE AND PAIN

Common variants at 5q33.1 predispose to migraine in African-American children

(2018) Xiao Chang et al.   JOURNAL OF MEDICAL GENETICS

Drosophila CaV2 channels harboring human migraine mutations cause synapse hyperexcitability that can be suppressed by inhibition of a Ca2+ store release pathway

(2018) Douglas J. Brusich et al.   PLoS Genetics

A novel ATP1A2 mutation in a patient with hypokalaemic periodic paralysis and CNS symptoms

(2018) Marisol Sampedro Castañeda et al.   BRAIN

Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK

(2018) Perrine Royal et al.   NEURON

Prdm16 is required for the maintenance of neural stem cells in the postnatal forebrain and their differentiation into ependymal cells

(2017) Issei S. Shimada et al.   GENES & DEVELOPMENT

Genetics of Migraine: Insights into the Molecular Basis of Migraine Disorders

(2017) Heidi G. Sutherland et al.   HEADACHE

Genome-wide compound heterozygote analysis highlights alleles associated with adult height in Europeans

(2017) Kaiyin Zhong et al.   HUMAN GENETICS

Family studies to find rare high risk variants in migraine

(2017) Rikke Dyhr Hansen et al.   JOURNAL OF HEADACHE AND PAIN

De novo exonic duplication of ATP1A2 in Italian patient with hemiplegic migraine: a case report

(2017) Stella Gagliardi et al.   JOURNAL OF HEADACHE AND PAIN

Rare and low-frequency coding variants alter human adult height

(2017) Eirini Marouli et al.   NATURE

Genome-wide association study identifies 112 new loci for body mass index in the Japanese population

(2017) Masato Akiyama et al.   NATURE GENETICS

Hyperpolarization-activated current I h in mouse trigeminal sensory neurons in a transgenic mouse model of familial hemiplegic migraine type-1

(2017) Francesca Eroli et al.   NEUROSCIENCE

Zinc transporter 3 (ZnT3) and vesicular zinc in central nervous system function

(2017) Brendan B. McAllister et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Pathophysiology of Migraine: A Disorder of Sensory Processing

(2017) Peter J. Goadsby et al.   PHYSIOLOGICAL REVIEWS

High-throughput electrophysiological assays for voltage gated ion channels using SyncroPatch 768PE

(2017) Tianbo Li et al.   PLoS One

Impaired K+ binding to glial glutamate transporter EAAT1 in migraine

(2017) Peter Kovermann et al.   Scientific Reports

Activity-dependent calcium, oxygen, and vascular responses in a mouse model of familial hemiplegic migraine type 1

(2016) Lila Khennouf et al.   ANNALS OF NEUROLOGY

Large-Scale Functional RNAi Screen in C. elegans Identifies TGF-β and Notch Signaling Pathways as Modifiers of CACNA1A

(2016) Maria da Conceição Pereira et al.   ASN Neuro

Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations

(2016) Anine H. Stam et al.   BRAIN

Recurrent coma and fever in familial hemiplegic migraine type 2. A prospective 15-year follow-up of a large family with a novel ATP1A2 mutation

(2016) N Pelzer et al.   CEPHALALGIA

Animal models of monogenic migraine

(2016) Shih-Pin Chen et al.   CEPHALALGIA

Early-onset familial hemiplegic migraine due to a novel SCN1A mutation

(2016) Chunxiang Fan et al.   CEPHALALGIA

A novel SCN1A mutation identified in a Chinese family with familial hemiplegic migraine: A case report

(2016) Yang Zhang et al.   CEPHALALGIA

Prevalence and characteristics of migraine in CADASIL

(2016) Stephanie Guey et al.   CEPHALALGIA

Defective glutamate and K+clearance by cortical astrocytes in familial hemiplegic migraine type 2

(2016) Clizia Capuani et al.   EMBO Molecular Medicine

TRPM8 and Migraine

(2016) Greg Dussor et al.   HEADACHE

Gene co-expression analysis identifies brain regions and cell types involved in migraine pathophysiology: a GWAS-based study using the Allen Human Brain Atlas

(2016) Else Eising et al.   HUMAN GENETICS

Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics

(2016) Adam E. Handel et al.   HUMAN MOLECULAR GENETICS

Cortical spreading depolarization: Pathophysiology, implications, and future directions

(2016) Daniel R. Kramer et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Biomarkers of migraine: Part 1 – Genetic markers

(2016) Natalia Kondratieva et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

(2016) Padhraig Gormley et al.   NATURE GENETICS

Prevalence of lifetime depression in a large hemiplegic migraine cohort

(2016) Mark A. Louter et al.   NEUROLOGY

Dual Function of NRP1 in Axon Guidance and Subcellular Target Recognition in Cerebellum

(2016) Ludovic Telley et al.   NEURON

Loss of inhibition by brain natriuretic peptide over P2X3 receptors contributes to enhanced spike firing of trigeminal ganglion neurons in a mouse model of familial hemiplegic migraine type-1

(2016) Anna Marchenkova et al.   NEUROSCIENCE

The Multifaceted Roles of PRDM16: Adipose Biology and Beyond

(2016) Jingyi Chi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Complicated Migraines

(2016) Alyssa E. Blumenfeld et al.   Seminars in Pediatric Neurology

The Revolution in Migraine Genetics: From Aching Channels Disorders to a Next-Generation Medicine

(2016) Simona Pellacani et al.   Frontiers in Cellular Neuroscience

Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor

(2016) Haig Aghajanian et al.   Nature Communications

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model

(2016) Pernille Bøttger et al.   Scientific Reports

PRRT2 Is a Key Component of the Ca 2+ -Dependent Neurotransmitter Release Machinery

(2016) Pierluigi Valente et al.   Cell Reports

TGF-β Signaling in Dopaminergic Neurons Regulates Dendritic Growth, Excitatory-Inhibitory Synaptic Balance, and Reversal Learning

(2016) Sarah X. Luo et al.   Cell Reports

Migraine genetics: from genome-wide association studies to translational insights

(2016) Padhraig Gormley et al.   Genome Medicine

Insights into the Pathology of the α2-Na+/K+-ATPase in Neurological Disorders; Lessons from Animal Models

(2016) Toke J. Isaksen et al.   Frontiers in Physiology

Next-generation sequencing identifies novelCACNA1Agene mutations in episodic ataxia type 2

(2016) Neven Maksemous et al.   Molecular Genetics & Genomic Medicine

CADASIL: Migraine, Encephalopathy, Stroke and Their Inter-Relationships

(2016) Rhea Yan Ying Tan et al.   PLoS One

The evolving spectrum ofPRRT2-associated paroxysmal diseases

(2015) Darius Ebrahimi-Fakhari et al.   BRAIN

The clinical and genetic heterogeneity of paroxysmal dyskinesias

(2015) Alice R. Gardiner et al.   BRAIN

Systematic re-evaluation of genes from candidate gene association studies in migraine using a large genome-wide association data set

(2015) Boukje de Vries et al.   CEPHALALGIA

The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample

(2015) Ann-Louise Esserlind et al.   CEPHALALGIA

Gene-based pleiotropy across migraine with aura and migraine without aura patient groups

(2015) Huiying Zhao et al.   CEPHALALGIA

The influence of genetic constitution on migraine drug responses

(2015) Anne Francke Christensen et al.   CEPHALALGIA

Common polygenic variation contributes to risk of migraine in the Norfolk Island population

(2015) A. J. Rodriguez-Acevedo et al.   HUMAN GENETICS

Strategies for fine-mapping complex traits

(2015) Sarah L. Spain et al.   HUMAN MOLECULAR GENETICS

TheSCN1AMutation Database: Updating Information and Analysis of the Relationships among Genotype, Functional Alteration, and Phenotype

(2015) Heng Meng et al.   HUMAN MUTATION

Human Disease Phenotypes Associated With Mutations in TREX1

(2015) Gillian I. Rice et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Association of genetic loci for migraine susceptibility in the she people of China

(2015) Qi-Fang Lin et al.   JOURNAL OF HEADACHE AND PAIN

Migraine: Multiple Processes, Complex Pathophysiology

(2015) R. Burstein et al.   JOURNAL OF NEUROSCIENCE

Migraine pathophysiology: lessons from mouse models and human genetics

(2015) Michel D Ferrari et al.   LANCET NEUROLOGY

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Meta-analysis of the heritability of human traits based on fifty years of twin studies

(2015) Tinca J C Polderman et al.   NATURE GENETICS

A method to predict the impact of regulatory variants from DNA sequence

(2015) Dongwon Lee et al.   NATURE GENETICS

Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants

(2015) R. Malik et al.   NEUROLOGY

ClinVar: public archive of interpretations of clinically relevant variants

(2015) Melissa J. Landrum et al.   NUCLEIC ACIDS RESEARCH

A replication study of GWAS findings in migraine identifies association in a Swedish case–control sample

(2014) Caroline Ran et al.   BMC Medical Genetics

A novel SLC2A1 mutation linking hemiplegic migraine with alternating hemiplegia of childhood

(2014) Claudia M Weller et al.   CEPHALALGIA

Replication study of previous migraine genome-wide association study findings in a Spanish sample of migraine with aura

(2014) Cèlia Sintas et al.   CEPHALALGIA

Benefit of carbamazepine in a patient with hemiplegic migraine associated withPRRT2mutation

(2014) Russell C Dale et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

A missense variant of the ATP1A2 gene is associated with a novel phenotype of progressive sensorineural hearing loss associated with migraine

(2014) Se-Kyung Oh et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The comorbid relationship between migraine and epilepsy: a systematic review and meta-analysis

(2014) M. R. Keezer et al.   EUROPEAN JOURNAL OF NEUROLOGY

Replication of Migraine GWAS Susceptibility Loci in Chinese Han Population

(2014) Xiaoping Fan et al.   HEADACHE

Nonmigraine-associated TRESK K+ channel variant C110R does not increase the excitability of trigeminal ganglion neurons

(2014) Zhaohua Guo et al.   JOURNAL OF NEUROPHYSIOLOGY

CRISPR-Cas systems for editing, regulating and targeting genomes

(2014) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Measuring the activity of protein variants on a large scale using deep mutational scanning

(2014) Douglas M Fowler et al.   Nature Protocols

PRRT2 and hemiplegic migraine: A complex association

(2014) N. Pelzer et al.   NEUROLOGY

A hyperexcitability phenotype in mouse trigeminal sensory neurons expressing the R192Q Cacna1a missense mutation of familial hemiplegic migraine type-1

(2014) S.K. Hullugundi et al.   NEUROSCIENCE

Properties, regulation, pharmacology, and functions of the K2P channel, TRESK

(2014) Péter Enyedi et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Regulates the Stability and Function of GluA1 α-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionic Acid (AMPA) Receptor in Neurons

(2014) Ming Gan et al.   PLoS One

Selectivity in Genetic Association with Sub-classified Migraine in Women

(2014) Daniel I. Chasman et al.   PLoS Genetics

Brain activations in the premonitory phase of nitroglycerin-triggered migraine attacks

(2013) Farooq Husain Maniyar et al.   BRAIN

Next generation sequencing for molecular diagnosis of neurological disorders using ataxias as a model

(2013) Andrea H. Németh et al.   BRAIN

Clinical spectrum in three families with familial hemiplegic migraine type 2 including a novel mutation in the ATP1A2 gene

(2013) Christian Roth et al.   CEPHALALGIA

Divergent effects of the T1174SSCN1Amutation associated with seizures and hemiplegic migraine

(2013) Sandrine Cestèle et al.   EPILEPSIA

Predicting the functional consequences of non-synonymous DNA sequence variants — evaluation of bioinformatics tools and development of a consensus strategy

(2013) Kimon Frousios et al.   GENOMICS

Genome-Wide-Associated Variants in Migraine Susceptibility: A Replication Study From North India

(2013) Jayashri Ghosh et al.   HEADACHE

The Prevalence of Familial Hemiplegic Migraine With Cerebellar Ataxia and Spinocerebellar Ataxia Type 6 in Portugal

(2013) José Barros et al.   HEADACHE

PRDM16 rs2651899 Variant Is a Risk Factor for Chinese Common Migraine Patients

(2013) Xing-Kai An et al.   HEADACHE

Low Density Lipoprotein Receptor-related Protein 1 (LRP1) ModulatesN-Methyl-d-aspartate (NMDA) Receptor-dependent Intracellular Signaling and NMDA-induced Regulation of Postsynaptic Protein Complexes

(2013) Chikako Nakajima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Wide Clinical Phenotype Spectrum in Patients With ATP1A2 Mutations

(2013) Bashaer Al-Bulushi et al.   JOURNAL OF CHILD NEUROLOGY

Functional Analysis of a Migraine-Associated TRESK K+ Channel Mutation

(2013) P. Liu et al.   JOURNAL OF NEUROSCIENCE

MTHFR C677T polymorphism and migraine risk: A meta-analysis

(2013) Ruozhuo Liu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Genome-wide meta-analysis identifies new susceptibility loci for migraine

(2013) Verneri Anttila et al.   NATURE GENETICS

Behavioral evidence for photophobia and stress-related ipsilateral head pain in transgenic Cacna1a mutant mice

(2013) Mona Lisa Chanda et al.   PAIN

Migraine pathophysiology: Anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain

(2013) Rodrigo Noseda et al.   PAIN

Identification of a Novel Nonsense Mutation p.Tyr1957Ter of CACNA1A in a Chinese Family with Episodic Ataxia 2

(2013) Yafang Hu et al.   PLoS One

Nonfunctional NaV1.1 familial hemiplegic migraine mutant transformed into gain of function by partial rescue of folding defects

(2013) S. Cestele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spreading Depression Triggers Headache by Activating Neuronal Panx1 Channels

(2013) H. Karatas et al.   SCIENCE

Casein Kinase I  Mutations in Familial Migraine and Advanced Sleep Phase

(2013) K. C. Brennan et al.   Science Translational Medicine

Power and Predictive Accuracy of Polygenic Risk Scores

(2013) Frank Dudbridge   PLoS Genetics

Screening ofCACNA1AandATP1A2genes in hemiplegic migraine: clinical, genetic, and functional studies

(2013) Oriel Carreño et al.   Molecular Genetics & Genomic Medicine

PRRT2 Mutations Cause Benign Familial Infantile Epilepsy and Infantile Convulsions with Choreoathetosis Syndrome

(2012) Sarah E. Heron et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pathophysiology of Migraine

(2012) Daniela Pietrobon et al.   Annual Review of Physiology

Endogenous Mechanisms Underlying the Activation and Sensitization of Meningeal Nociceptors: The Role of Immuno-Vascular Interactions and Cortical Spreading Depression

(2012) Dan Levy   Current Pain and Headache Reports

Familial and Sporadic Hemiplegic Migraine: Diagnosis and Treatment

(2012) Nadine Pelzer et al.   Current Treatment Options in Neurology

Familial PRRT2 mutation with heterogeneous paroxysmal disorders including paroxysmal torticollis and hemiplegic migraine

(2012) RUSSELL C DALE et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Migraine headache: a review of the molecular genetics of a common disorder

(2012) Cherubino Di Lorenzo et al.   JOURNAL OF HEADACHE AND PAIN

Mutations in PRRT2 responsible for paroxysmal kinesigenic dyskinesias also cause benign familial infantile convulsions

(2012) Shinji Ono et al.   JOURNAL OF HUMAN GENETICS

Bayesian refinement of association signals for 14 loci in 3 common diseases

(2012) Julian B Maller et al.   NATURE GENETICS

Genome-wide association analysis identifies susceptibility loci for migraine without aura

(2012) Tobias Freilinger et al.   NATURE GENETICS

A genome-wide analysis of 'Bounty' descendants implicates several novel variants in migraine susceptibility

(2012) Hannah C. Cox et al.   NEUROGENETICS

PRRT2 mutations in familial infantile seizures, paroxysmal dyskinesia, and hemiplegic migraine

(2012) C. Marini et al.   NEUROLOGY

PRRT2 mutations cause hemiplegic migraine

(2012) F. Riant et al.   NEUROLOGY

SIFT web server: predicting effects of amino acid substitutions on proteins

(2012) Ngak-Leng Sim et al.   NUCLEIC ACIDS RESEARCH

Migraine: a disorder of brain excitatory–inhibitory balance?

(2012) Dania Vecchia et al.   TRENDS IN NEUROSCIENCES

Functional analysis of missense variants in the TRESK (KCNK18) K+ channel

(2012) Isabelle Andres-Enguix et al.   Scientific Reports

Mutations in the Gene PRRT2 Cause Paroxysmal Kinesigenic Dyskinesia with Infantile Convulsions

(2012) Hsien-Yang Lee et al.   Cell Reports

LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer's disease

(2012) Carlos Spuch et al.   Frontiers in Physiology

Methylenetetrahydrofolate Reductase Gene Variant (MTHFR C677T) and Migraine: A Case Control Study and Meta-analysis

(2011) Zainab Samaan et al.   BMC Neurology

Identification of PRRT2 as the causative gene of paroxysmal kinesigenic dyskinesias

(2011) J.-L. Wang et al.   BRAIN

Exome Sequencing of Ion Channel Genes Reveals Complex Profiles Confounding Personal Risk Assessment in Epilepsy

(2011) Tara Klassen et al.   CELL

The genetics of Dravet syndrome

(2011) Carla Marini et al.   EPILEPSIA

Trigeminal Nociceptive Transmission in Migraineurs Predicts Migraine Attacks

(2011) A. Stankewitz et al.   JOURNAL OF NEUROSCIENCE

TGF-β signaling in endothelial cells, but not neuroepithelial cells, is essential for cerebral vascular development

(2011) Ha-Long Nguyen et al.   LABORATORY INVESTIGATION

Sporadic and familial hemiplegic migraine: pathophysiological mechanisms, clinical characteristics, diagnosis, and management

(2011) Michael Bjørn Russell et al.   LANCET NEUROLOGY

Identification of molecular genetic factors that influence migraine

(2011) Bridget H. Maher et al.   MOLECULAR GENETICS AND GENOMICS

Exome sequencing identifies truncating mutations in PRRT2 that cause paroxysmal kinesigenic dyskinesia

(2011) Wan-Jin Chen et al.   NATURE GENETICS

Genome-wide association study reveals three susceptibility loci for common migraine in the general population

(2011) Daniel I Chasman et al.   NATURE GENETICS

Increased Susceptibility to Cortical Spreading Depression in the Mouse Model of Familial Hemiplegic Migraine Type 2

(2011) Loredana Leo et al.   PLoS Genetics

Discrete Change in Volatile Anesthetic Sensitivity in Mice with Inactivated Tandem Pore Potassium Ion Channel TRESK

(2010) Yun Jeong Chae et al.   ANESTHESIOLOGY

Activation of central trigeminovascular neurons by cortical spreading depression

(2010) XiChun Zhang et al.   ANNALS OF NEUROLOGY

CADASIL and migraine: A narrative review

(2010) Michael K Liem et al.   CEPHALALGIA

Impaired plasma membrane targeting or protein stability by certain ATP1A2 mutations identified in sporadic or familial hemiplegic migraine

(2010) Neslihan N. Tavraz et al.   Channels

Sodium channel SCN1A and epilepsy: Mutations and mechanisms

(2010) Andrew Escayg et al.   EPILEPSIA

Endogenous SNAP-25 Regulates Native Voltage-gated Calcium Channels in Glutamatergic Neurons

(2010) Steven B. Condliffe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Frequencies of genetic polymorphisms related to triptans metabolism in chronic migraine

(2010) Giovanna Gentile et al.   JOURNAL OF HEADACHE AND PAIN

Pain channelopathies

(2010) Roman Cregg et al.   JOURNAL OF PHYSIOLOGY-LONDON

Identification of novel and recurrent CACNA1A gene mutations in fifteen patients with episodic ataxia type 2

(2010) Elide Mantuano et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress

(2010) Sergei Chuikov et al.   NATURE CELL BIOLOGY

Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1

(2010) Verneri Anttila et al.   NATURE GENETICS

A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura

(2010) Ronald G Lafrenière et al.   NATURE MEDICINE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

MutationTaster evaluates disease-causing potential of sequence alterations

(2010) Jana Marie Schwarz et al.   NATURE METHODS

De novo mutations in ATP1A2 and CACNA1A are frequent in early-onset sporadic hemiplegic migraine

(2010) F. Riant et al.   NEUROLOGY

Glutamate transporters: Diversity, function, and involvement in neurologic disease

(2010) E. E. Benarroch   NEUROLOGY

Defective membrane expression of the Na+-HCO3- cotransporter NBCe1 is associated with familial migraine

(2010) M. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Next generation tools for the annotation of human SNPs

(2009) Rachel Karchin   BRIEFINGS IN BIOINFORMATICS

Migraine and Genetic and Acquired Vasculopathies

(2009) AH Stam et al.   CEPHALALGIA

Migraine and the Hypothalamus

(2009) KB Alstadhaug   CEPHALALGIA

MTHFR677C>T andACED/I Polymorphisms in Migraine: A Systematic Review and Meta-Analysis

(2009) Markus Schürks et al.   HEADACHE

Molecular genetics of migraine

(2009) Boukje de Vries et al.   HUMAN GENETICS

Large scale calcium channel gene rearrangements in episodic ataxia and hemiplegic migraine: implications for diagnostic testing

(2009) R W Labrum et al.   JOURNAL OF MEDICAL GENETICS

CADASIL

(2009) Hugues Chabriat et al.   LANCET NEUROLOGY

Enhanced Excitatory Transmission at Cortical Synapses as the Basis for Facilitated Spreading Depression in CaV2.1 Knockin Migraine Mice

(2009) Angelita Tottene et al.   NEURON

First Mutation in the Voltage-Gated Nav1.1 Subunit Gene SCN1A with Co-Occurring Familial Hemiplegic Migraine and Epilepsy

(2008) M-J Castro et al.   CEPHALALGIA

Diverse Functional Consequences of Mutations in the Na+/K+-ATPase α2-Subunit Causing Familial Hemiplegic Migraine Type 2

(2008) Neslihan N. Tavraz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Self-Limited Hyperexcitability: Functional Effect of a Familial Hemiplegic Migraine Mutation of the Nav1.1 (SCN1A) Na+ Channel

(2008) S. Cestele et al.   JOURNAL OF NEUROSCIENCE

Divergent sodium channel defects in familial hemiplegic migraine

(2008) K. M. Kahlig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spinocerebellar ataxia type 6 knockin mice develop a progressive neuronal dysfunction with age-dependent accumulation of mutant CaV2.1 channels

(2008) K. Watase et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of the C677T Polymorphism in the MTHFR Gene with Migraine: A Meta-Analysis

(2007) E Rubino et al.   CEPHALALGIA

Epilepsy as part of the phenotype associated withATP1A2mutations

(2007) Liesbet Deprez et al.   EPILEPSIA