Tumor-Derived Exosomes Mediate the Instability of Cadherins and Promote Tumor Progression

Effects of Gastric Cancer Cell-Derived Exosomes on the Immune Regulation of Mesenchymal Stem Cells by the NF-kB Signaling Pathway

(2019) Yamei Shen et al.   STEM CELLS AND DEVELOPMENT

Reassessment of Exosome Composition

(2019) Dennis K. Jeppesen et al.   CELL

Hypoxic tumor-derived exosomal miR-301a mediates M2 macrophage polarization via PTEN/PI3Kγ to promote pancreatic cancer metastasis

(2018) Xiaofeng Wang et al.   CANCER RESEARCH

Hepatoma cell-secreted exosomal microRNA-103 increases vascular permeability and promotes metastasis by targeting junction proteins

(2018) Jian-Hong Fang et al.   HEPATOLOGY

Thyroid cancer stem-like cell exosomes: regulation of EMT via transfer of lncRNAs

(2018) Heather Hardin et al.   LABORATORY INVESTIGATION

Tumor-originated exosomal lncUEGC1 as a circulating biomarker for early-stage gastric cancer

(2018) Ling-Yun Lin et al.   Molecular Cancer

Emerging role of exosome-derived long non-coding RNAs in tumor microenvironment

(2018) Zhenqiang Sun et al.   Molecular Cancer

FGFR1-ERK1/2-SOX2 axis promotes cell proliferation, epithelial–mesenchymal transition, and metastasis in FGFR1-amplified lung cancer

(2018) Kaixuan Wang et al.   ONCOGENE

Tumor-derived exosomal lnc-Sox2ot promotes EMT and stemness by acting as a ceRNA in pancreatic ductal adenocarcinoma

(2018) Zhonghu Li et al.   ONCOGENE

Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A

(2018) Kyoko Hashimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-Induced Matrix Metalloproteinase-13 Expression in Exosomes from Nasopharyngeal Carcinoma Enhances Metastases

(2018) Ying Shan et al.   Cell Death & Disease

Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface

(2018) Maggie K. S. Tang et al.   Nature Communications

Loss of exosomal miR-148b from cancer-associated fibroblasts promotes endometrial cancer cell invasion and cancer metastasis

(2018) Bi-Lan Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Melittin-induced long non-coding RNA NONHSAT105177 inhibits proliferation and migration of pancreatic ductal adenocarcinoma

(2018) Xinjing Wang et al.   Cell Death & Disease

TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression

(2018) Dong-ming Wu et al.   Cancer Medicine

Alterations in exosomal miRNA profile upon epithelial-mesenchymal transition in human lung cancer cell lines

(2018) Yue-Ting Tang et al.   BMC GENOMICS

Glycomics of prostate cancer: updates

(2018) Jan Tkac et al.   Expert Review of Proteomics

Carcinogenic epithelial-mesenchymal transition initiated by oral cancer exosomes is inhibited by anti-EGFR antibody cetuximab

(2018) Toshifumi Fujiwara et al.   ORAL ONCOLOGY

Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells

(2017) Nikolina Dioufa et al.   Molecular Cancer

Hypoxic exosomes facilitate bladder tumor growth and development through transferring long non-coding RNA-UCA1

(2017) Mei Xue et al.   Molecular Cancer

Lipids in exosomes: Current knowledge and the way forward

(2017) Tore Skotland et al.   PROGRESS IN LIPID RESEARCH

SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 - and RB1 -deficient prostate cancer

(2017) Ping Mu et al.   SCIENCE

The role of exosomes in cancer metastasis

(2017) Teresa Bernadette Steinbichler et al.   SEMINARS IN CANCER BIOLOGY

UBR2 Enriched in p53 Deficient Mouse Bone Marrow Mesenchymal Stem Cell-Exosome Promoted Gastric Cancer Progression via Wnt/β-Catenin Pathway

(2017) Jiahui Mao et al.   STEM CELLS

Cadherin 6 is activated by Epstein–Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma

(2017) L-L Zuo et al.   Oncogenesis

Genetic Mutation and Exosome Signature of Human Papilloma Virus Associated Oropharyngeal Cancer

(2017) Anbarasu Kannan et al.   Scientific Reports

Exosomes from metastatic cancer cells transfer amoeboid phenotype to non-metastatic cells and increase endothelial permeability: their emerging role in tumor heterogeneity

(2017) Odessa Schillaci et al.   Scientific Reports

Exosome cargo reflects TGF-β1-mediated epithelial-to-mesenchymal transition (EMT) status in A549 human lung adenocarcinoma cells

(2016) Jiyeon Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

lncRNAs and microRNAs with a role in cancer development

(2016) Julia Liz et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Exosomes Derived from Hypoxic Oral Squamous Cell Carcinoma Cells Deliver miR-21 to Normoxic Cells to Elicit a Prometastatic Phenotype

(2016) Ling Li et al.   CANCER RESEARCH

Circulating miRNAs with prognostic value in metastatic breast cancer and for early detection of metastasis

(2016) Dharanija Madhavan et al.   CARCINOGENESIS

Epithelial–mesenchymal transition (EMT) and metastasis: yes, no, maybe?

(2016) Maren Diepenbruck et al.   CURRENT OPINION IN CELL BIOLOGY

Beyond a tumor suppressor: Soluble E-cadherin promotes the progression of cancer

(2016) Qi-Ping Hu et al.   INTERNATIONAL JOURNAL OF CANCER

New Concepts in Cancer Biomarkers: Circulating miRNAs in Liquid Biopsies

(2016) Erika Larrea et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The biology and function of exosomes in cancer

(2016) Raghu Kalluri   JOURNAL OF CLINICAL INVESTIGATION

LncRNA-ATB mediated E-cadherin repression promotes the progression of colon cancer and predicts poor prognosis

(2016) Ben Yue et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Differential expression of the epithelial mesenchymal transition factors Snail, Slug, Twist, TGF-β, and E-cadherin in ameloblastoma

(2016) Kagami Kurioka et al.   Medical Molecular Morphology

Roles for E-cadherin cell surface regulation in cancer

(2016) Yuliya I. Petrova et al.   MOLECULAR BIOLOGY OF THE CELL

Exosomes Promote Ovarian Cancer Cell Invasion through Transfer of CD44 to Peritoneal Mesothelial Cells

(2016) Koji Nakamura et al.   MOLECULAR CANCER RESEARCH

IL-33 promotes growth and liver metastasis of colorectal cancer in mice by remodeling the tumor microenvironment and inducing angiogenesis

(2016) Yu Zhang et al.   MOLECULAR CARCINOGENESIS

Unique features of long non-coding RNA biogenesis and function

(2016) Jeffrey J. Quinn et al.   NATURE REVIEWS GENETICS

Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy

(2016) M Gugnoni et al.   ONCOGENE

Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation

(2016) Silvana Sandri et al.   PHARMACOLOGICAL RESEARCH

Crosstalk between TGF-β signaling and miRNAs in breast cancer metastasis

(2016) Wei Chen et al.   TUMOR BIOLOGY

Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts

(2016) S Baroni et al.   Cell Death & Disease

KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes

(2016) Andrew J. McKenzie et al.   Cell Reports

Expression of the Long Non-Coding RNA HOTAIR Correlates with Disease Progression in Bladder Cancer and Is Contained in Bladder Cancer Patient Urinary Exosomes

(2016) Claudia Berrondo et al.   PLoS One

Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression

(2015) Suman Dutta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Effects of Decitabine on Invasion and Exosomal Expression of miR-200c and miR-141 in Oxaliplatin-Resistant Colorectal Cancer Cells

(2015) Shota Tanaka et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression

(2015) Sinéad T Aherne et al.   BMC CANCER

PDLIM1 Stabilizes the E-Cadherin/ -Catenin Complex to Prevent Epithelial-Mesenchymal Transition and Metastatic Potential of Colorectal Cancer Cells

(2015) H.-N. Chen et al.   CANCER RESEARCH

Matrix metalloproteinase 13-containing exosomes promote nasopharyngeal carcinoma metastasis

(2015) Yiwen You et al.   CANCER SCIENCE

Evf2lncRNA/BRG1/DLX1 interactions reveal RNA-dependent inhibition of chromatin remodeling

(2015) Ivelisse Cajigas et al.   DEVELOPMENT

Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces

(2015) Elena Scarpa et al.   DEVELOPMENTAL CELL

N-cadherin promotes epithelial-mesenchymal transition and cancer stem cell-like traits via ErbB signaling in prostate cancer cells

(2015) MIN WANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Long Non-coding RNAs (LncRNA) Regulated by Transforming Growth Factor (TGF) β

(2015) Edward J. Richards et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-cadherin functions as a growth suppressor in a model of K-ras-induced PanIN

(2015) Y Su et al.   ONCOGENE

MicroRNA-224 promotes tumor progression in nonsmall cell lung cancer

(2015) Ri Cui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes

(2015) Ken Tajima et al.   Nature Communications

LncRNA HOTAIR Enhances the Androgen-Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer

(2015) Ali Zhang et al.   Cell Reports

Epithelial Plasticity in Cancer: Unmasking a MicroRNA Network for TGF-β-, Notch-, and Wnt-Mediated EMT

(2015) Eugenio Zoni et al.   Journal of Oncology

Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods

(2015) Tamás Baranyai et al.   PLoS One

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

(2014) Sonia A. Melo et al.   CANCER CELL

Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor

(2014) Hyungsoon Im et al.   NATURE BIOTECHNOLOGY

Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization

(2014) G Canesin et al.   ONCOGENE

Long Noncoding RNA-EBIC Promotes Tumor Cell Invasion by Binding to EZH2 and Repressing E-Cadherin in Cervical Cancer

(2014) Ning-xia Sun et al.   PLoS One

SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal network

(2013) Xuefei Li et al.   CANCER LETTERS

Long non-coding RNA H19 increases bladder cancer metastasis by associating with EZH2 and inhibiting E-cadherin expression

(2013) Ming Luo et al.   CANCER LETTERS

FGF Receptors: Cancer Biology and Therapeutics

(2013) Masaru Katoh et al.   MEDICINAL RESEARCH REVIEWS

Soluble E-cadherin: a critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling

(2013) S M Brouxhon et al.   ONCOGENE

Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury

(2013) Fatih Arslan et al.   Stem Cell Research

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease

(2012) Irfan A. Qureshi et al.   NATURE REVIEWS NEUROSCIENCE

Tumor-Recruited Neutrophils and Neutrophil TIMP-Free MMP-9 Regulate Coordinately the Levels of Tumor Angiogenesis and Efficiency of Malignant Cell Intravasation

(2011) Erin M. Bekes et al.   AMERICAN JOURNAL OF PATHOLOGY

ExoCarta 2012: database of exosomal proteins, RNA and lipids

(2011) S. Mathivanan et al.   NUCLEIC ACIDS RESEARCH

Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling

(2010) Arthit Chairoungdua et al.   JOURNAL OF CELL BIOLOGY

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

(2010) Sihem Cheloufi et al.   NATURE

E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer

(2009) Otto Schmalhofer et al.   CANCER AND METASTASIS REVIEWS

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Abundant conserved microRNA target sites in the 5′-untranslated region and coding sequence

(2009) Xue Zhou et al.   GENETICA

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

(2008) Douglas D. Taylor et al.   GYNECOLOGIC ONCOLOGY

Cadherin switching

(2008) M. J. Wheelock et al.   JOURNAL OF CELL SCIENCE

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY