IL-33 promotes growth and liver metastasis of colorectal cancer in mice by remodeling the tumor microenvironment and inducing angiogenesis

IL-33 facilitates oncogene-induced cholangiocarcinoma in mice by an interleukin-6-sensitive mechanism

(2015) Daisaku Yamada et al.   HEPATOLOGY

IL-33 activates tumor stroma to promote intestinal polyposis

(2015) Rebecca L. Maywald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation

(2015) E. Suzanne Cohen et al.   Nature Communications

Comprehensive analysis of β-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/β-catenin signaling

(2014) Andreas Herbst et al.   BMC GENOMICS

Dynamics of the IL-33/ST2 network in the progression of human colorectal adenoma to sporadic colorectal cancer

(2014) Guanglin Cui et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

BCR-ABL-Induced Deregulation of the IL-33/ST2 Pathway in CD34(+) Progenitors from Chronic Myeloid Leukemia Patients

(2014) A. Levescot et al.   CANCER RESEARCH

Tumoral Expression of IL-33 Inhibits Tumor Growth and Modifies the Tumor Microenvironment through CD8+T and NK Cells

(2014) Xin Gao et al.   JOURNAL OF IMMUNOLOGY

IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice

(2014) R Guabiraba et al.   Mucosal Immunology

High Serum Levels of the Interleukin-33 Receptor Soluble ST2 as a Negative Prognostic Factor in Hepatocellular Carcinoma

(2014) Dominik Bergis et al.   Translational Oncology

Serum IL-33 as a Diagnostic and Prognostic Marker in Non-small Cell Lung Cancer

(2013) Liang-An Hu et al.   Asian Pacific Journal of Cancer Prevention

Transgenic expression of IL-33 activates CD8+ T cells and NK cells and inhibits tumor growth and metastasis in mice

(2013) Kun Gao et al.   CANCER LETTERS

Development and characterization of a reliable mouse model of colorectal cancer metastasis to the liver

(2013) Yu Zhang et al.   CLINICAL & EXPERIMENTAL METASTASIS

The paracrine effect of cancer-associated fibroblast-induced interleukin-33 regulates the invasiveness of head and neck squamous cell carcinoma

(2013) Su-Feng Chen et al.   JOURNAL OF PATHOLOGY

Recruitment of myeloid cells to the tumor microenvironment supports liver metastasis

(2013) Su Yin Lim et al.   OncoImmunology

Interleukin-33 Drives a Proinflammatory Endothelial Activation That Selectively Targets Nonquiescent Cells

(2012) Jürgen Pollheimer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Improved efficacy of a novel anti-angiogenic drug combination (TL-118) against colorectal-cancer liver metastases; MRI monitoring in mice

(2012) Y Edrei et al.   BRITISH JOURNAL OF CANCER

Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer

(2012) Lauren J. Bayne et al.   CANCER CELL

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

Interleukin-33 acts as a pro-inflammatory cytokine and modulates its receptor gene expression in highly metastatic human pancreatic carcinoma cells

(2012) Annett Schmieder et al.   CYTOKINE

Alarmins: awaiting a clinical response

(2012) James K. Chan et al.   JOURNAL OF CLINICAL INVESTIGATION

The Alarmin Interleukin-33 Drives Protective Antiviral CD8+ T Cell Responses

(2012) W. V. Bonilla et al.   SCIENCE

The Immune-Modulating Cytokine and Endogenous Alarmin Interleukin-33 Is Upregulated in Skin Exposed to Inflammatory UVB Radiation

(2011) Scott Napier Byrne et al.   AMERICAN JOURNAL OF PATHOLOGY

Intestinal inflammatory cytokine response in relation to tumorigenesis in the ApcMin/+ mouse

(2011) Jamie L. McClellan et al.   CYTOKINE

Serum Interleukin-33 Levels in Patients with Gastric Cancer

(2011) Pinghu Sun et al.   DIGESTIVE DISEASES AND SCIENCES

Role of IL-33 in inflammation and disease

(2011) Ashley M Miller   Journal of Inflammation-London

S100A8/A9 Activate Key Genes and Pathways in Colon Tumor Progression

(2011) M. Ichikawa et al.   MOLECULAR CANCER RESEARCH

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

NF-κB Signaling Pathway, Inflammation and Colorectal Cancer

(2010) Soly Wang et al.   Cellular & Molecular Immunology

The enigmatic processing and secretion of interleukin-33

(2010) Weihua Zhao et al.   Cellular & Molecular Immunology

Inflammation and Colon Cancer

(2010) Janoš Terzić et al.   GASTROENTEROLOGY

Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy

(2009) S. J. Priceman et al.   BLOOD

Interleukin-33 induces angiogenesis and vascular permeability through ST2/TRAF6-mediated endothelial nitric oxide production

(2009) Y.-S. Choi et al.   BLOOD

New insights into the aetiology of colorectal cancer from genome-wide association studies

(2009) Albert Tenesa et al.   NATURE REVIEWS GENETICS

The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

(2009) C. Cayrol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-33 – cytokine of dual function or novel alarmin?

(2009) Guttorm Haraldsen et al.   TRENDS IN IMMUNOLOGY

Stromal Fibroblasts Activated by Tumor Cells Promote Angiogenesis in Mouse Gastric Cancer

(2008) Xiaoying Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

(2008) Sachie Hiratsuka et al.   NATURE CELL BIOLOGY

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

(2008) Christine Moussion et al.   PLoS One

Risk for colorectal cancer in ulcerative colitis: Changes, causes and management strategies

(2008) Peter Laszlo Lakatos et al.   WORLD JOURNAL OF GASTROENTEROLOGY