UBR2 Enriched in p53 Deficient Mouse Bone Marrow Mesenchymal Stem Cell-Exosome Promoted Gastric Cancer Progression via Wnt/β-Catenin Pathway

Antioxidant properties of mesenchymal stem cells against oxidative stress in a murine model of colitis

(2016) Fabiany da Costa Gonçalves et al.   BIOTECHNOLOGY LETTERS

Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP

(2016) Min Lu et al.   CANCER CELL

Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: Involvement in cancer invasion and metastasis

(2016) Marco Cordani et al.   CANCER LETTERS

National estimates of cancer prevalence in China, 2011

(2016) Rongshou Zheng et al.   CANCER LETTERS

p53 functional deficiency in human colon cancer cells promotes fibroblast-mediated angiogenesis and tumor growth

(2016) Yoshito Hayashi et al.   CARCINOGENESIS

p53 pathway dysfunction is highly prevalent in acute myeloid leukemia independent of TP53 mutational status

(2016) A Quintás-Cardama et al.   LEUKEMIA

P53 expression correlates with poorer survival and augments the negative prognostic effect of MYC rearrangement, expression or concurrent MYC/BCL2 expression in diffuse large B-cell lymphoma

(2016) Xuan J Wang et al.   MODERN PATHOLOGY

MYC Mediates mRNA Cap Methylation of Canonical Wnt/β-Catenin Signaling Transcripts By Recruiting CDK7 and RNA Methyltransferase

(2016) Valeriya Posternak et al.   MOLECULAR CANCER RESEARCH

Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets

(2016) Yufang Shi et al.   NATURE REVIEWS DRUG DISCOVERY

The Influence of Ionizing Radiation on Exosome Composition, Secretion and Intercellular Communication

(2016) Karol Jelonek et al.   PROTEIN AND PEPTIDE LETTERS

HucMSC Exosome-Delivered 14-3-3ζ Orchestrates Self-Control of the Wnt Response via Modulation of YAP During Cutaneous Regeneration

(2016) Bin Zhang et al.   STEM CELLS

Mesenchymal Stem Cells are Recruited and Activated into Carcinoma-Associated Fibroblasts by Prostate Cancer Microenvironment-Derived TGF-β1

(2016) Pedro Barcellos-de-Souza et al.   STEM CELLS

Exosomes derived from gastric cancer cells activate NF-κB pathway in macrophages to promote cancer progression

(2016) Lijun Wu et al.   TUMOR BIOLOGY

Prognostic value of p53 mutation for poor outcome of Asian primary liver cancer patients: evidence from a cohort study and meta-analysis of 988 patients

(2016) Xiajie Wen et al.   OncoTargets and Therapy

miR-155-5p inhibition promotes the transition of bone marrow mesenchymal stem cells to gastric cancer tissue derived MSC-like cells via NF-κB p65 activation

(2016) Mengchu Zhu et al.   Oncotarget

Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3

(2016) Bing Tu et al.   Oncotarget

Exosomes in cancer: small particle, big player

(2015) Xu Zhang et al.   Journal of Hematology & Oncology

HucMSC-Exosome Mediated-Wnt4 Signaling Is Required for Cutaneous Wound Healing

(2015) Bin Zhang et al.   STEM CELLS

Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts

(2015) Ridwana Chowdhury et al.   Oncotarget

Mouse bone marrow-derived mesenchymal stem cells induce macrophage M2 polarization through the nuclear factor-κB and signal transducer and activator of transcription 3 pathways

(2014) Shuo Gao et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment

(2014) J Mao et al.   Cell Death & Disease

Signaling mechanism of tumor cell-induced up-regulation of E3 ubiquitin ligase UBR2

(2013) Guohua Zhang et al.   FASEB JOURNAL

Tumor-derived exosomes are enriched in ΔNp73, which promotes oncogenic potential in acceptor cells and correlates with patient survival

(2013) Beatriz Soldevilla et al.   HUMAN MOLECULAR GENETICS

Gastric Cancer Exosomes Trigger Differentiation of Umbilical Cord Derived Mesenchymal Stem Cells to Carcinoma-Associated Fibroblasts through TGF-β/Smad Pathway

(2012) Jianmei Gu et al.   PLoS One

Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Liver Fibrosis

(2012) Tingfen Li et al.   STEM CELLS AND DEVELOPMENT

Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway

(2010) Kanako Kume et al.   GENES TO CELLS

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C

(2010) Chieh Hsu et al.   JOURNAL OF CELL BIOLOGY

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

(2010) Ruenn Chai Lai et al.   Stem Cell Research

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

p53 Regulation of the IGF-1/AKT/mTOR Pathways and the Endosomal Compartment

(2009) Z. Feng   Cold Spring Harbor Perspectives in Biology

Oncogenic Pathway Combinations Predict Clinical Prognosis in Gastric Cancer

(2009) Chia Huey Ooi et al.   PLoS Genetics

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY