Article
Multidisciplinary Sciences
Ke Mo, Yu Zhang, Zheng Dong, Yuhang Yang, Xiaoqiang Ma, Ben L. Feringa, Depeng Zhao
Summary: Scientists have designed synthetic molecular motors that can be driven by chemical energy and have intrinsic control over the direction of rotation, simple autonomous motion, and near-perfect unidirectionality. This study demonstrates the potential for future generations of multicomponent machines to perform mechanical functions.
Article
Engineering, Biomedical
Ruslan Garifullin, Mustafa O. Guler
Summary: This review discusses the use of self-assembling peptide molecules and electroactive units in supramolecular functional electronic and optical materials, with potential biomedical and bioelectronics applications.
MATERIALS TODAY BIO
(2021)
Review
Biochemistry & Molecular Biology
Traian Constantin, Mihai Pavalean, Stefana Bucur, Maria Magdalena Constantin, Alin Codrut Nicolescu, Irina Pacu, Victor Madan
Summary: Bladder cancer animal models can be categorized as either autochthonous or non-autochthonous, with the non-autochthonous models further classified into syngeneic and xenograft models. These models have different characteristics and applications based on the type of tumor implantation.
Article
Engineering, Multidisciplinary
Mariusz Ksiazek
Summary: The author explores the potential use of polymerized sulfur waste as a biocompatible material in biomaterial production, particularly in surgical applications. Experimental studies have demonstrated that polymerized sulfur waste shows promise as a biocomposite, opening up new possibilities for the industry.
COMPOSITES PART B-ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Alana N. Vagnozzi, Jian-Guo Li, Jin Chiu, Roshanak Razmpour, Rebecca Warfield, Servio H. Ramirez, Domenico Pratico
Summary: VPS35 plays a crucial role in tau metabolism and neuropathology, with its overexpression reducing pathological tau in neuronal cells while genetic silencing leads to accumulation. The availability of active cathepsin D mediates the effect of VPS35 on pathological tau accumulation, making it a potential therapeutic target for human tauopathies.
MOLECULAR PSYCHIATRY
(2021)
Article
Behavioral Sciences
Etedal Ahmed A. Ibrahim, Ghada A. Mutaal Badri, Khabab Abbasher Hussien Mohamed Ahmed, Mohammed Eltahier Abdalla Omer
Summary: The study found that environmental conditions were the most common triggers of migraine headache among Sudanese patients, while Acetaminophen was the most commonly used drug for relieving migraine in this population. The majority of patients were female (80%), aged 26-35 years (56.9%), and a significant proportion were housewives (40%).
BRAIN AND BEHAVIOR
(2021)
Review
Humanities, Multidisciplinary
Ahmad Fekry Moussa, Ibrahim Suleiman Al Qatawneh, Moustafa Elmetwaly Kandeel
Summary: This study focuses on the procedural necessity of primary investigations in the Arab countries, particularly in Egypt. It analyzes the position of the Arab procedural legislation and judiciary systems regarding procedural necessity and argues against expanding discretionary powers that may lead to abuse of officials and restrict individual rights and freedoms.
HUMANITIES & SOCIAL SCIENCES COMMUNICATIONS
(2022)
Article
Environmental Sciences
Yin Lu, Qin Ma, Xiaolu Xu, Zhefu Yu, Tianjiao Guo, Yangkai Wu
Summary: The study showed that exposure to poly styrene microplastics (PS-MPs) can lead to increased apoptosis and cell death, higher micronucleus rate, and reduced mitotic index in V. faba root cells. Additionally, it causes significant oxidative stress by altering the expression of antioxidant enzymes and genes related to cell cycle and DNA repair.
ENVIRONMENTAL POLLUTION
(2021)
Article
Physics, Multidisciplinary
Gabriel Koch Ocker
Summary: This study presents a statistical field theory for networks of integrate-and-fire neurons with stochastic spike emission, revealing the impact of spike-driven reset of the membrane voltage on population activity. The study uncovers bistability and fluctuation effects in the mean-field dynamics, as well as the roles of spike resets and recurrent inhibition in stabilizing network activity. It also calculates the phase diagram for inhibitory stabilization and finds that wide regions of parameter space exhibit inhibition-stabilized regime.
Article
Engineering, Chemical
James Dufty, Jeffrey Wrighton, Kai Luo
Summary: This article considers definitions for local pressure in an inhomogeneous fluid, covering both equilibrium and local equilibrium states, and reconciles thermodynamic and mechanical (hydrodynamic) contexts. Remaining problems and uncertainties in the topic are also discussed.
Article
Multidisciplinary Sciences
Peter C. Chu
Summary: In ocean dynamics, two different treatments are found for horizontal pressure gradient force and gravity, with vertical component being much larger than horizontal in both cases. Horizontal pressure gradient force is considered dominant, while horizontal gravity is completely omitted in oceanography. The importance of horizontal gravity is identified using a non-dimensional C number, with global data showing an unexpectedly large C number around 24.
SCIENTIFIC REPORTS
(2021)
Article
Education & Educational Research
Olga Garanina, Nidal Al Said, Valery Stepenko, Marija Troyanskaya
Summary: The study developed and tested an original model illustrating personality development in the information society, finding that its implementation increased students' use of resources for personal growth. The model's practical value lies in its applicability to higher education systems in various countries, especially in the context of distance learning and social isolation caused by the COVID-19 pandemic.
EDUCATION AND INFORMATION TECHNOLOGIES
(2021)
Article
Agricultural Engineering
Jiangkuan Xing, Ryoichi Kurose, Kun Luo, Jianren Fan
Summary: Researchers have developed a new tool for establishing solid fuel conversion kinetics from thermogravimetric analysis (TGA) measurements using chemistry-informed machine learning approaches. The derived pyrolysis kinetics accurately reproduce the pyrolysis process for different biomass types and demonstrate advantages in predicting volatiles yield.
BIORESOURCE TECHNOLOGY
(2022)
Article
Clinical Neurology
Julian Klingbeil, Max-Lennart Brandt, Max Wawrzyniak, Anika Stockert, Hans R. Schneider, Petra Baum, Karl-Titus Hoffmann, Dorothee Saur
Summary: Lesions in the left ventrolateral prefrontal cortex increase the risk of depressive symptoms 6 months poststroke, while lesions within the right hemisphere are unrelated to depressive symptoms. Early prediction factors for poststroke depression include depressive symptoms within the first 4 weeks poststroke.
Article
Multidisciplinary Sciences
Muhammad Aslam
Summary: A new F-test method for two counts data from the Poisson distribution under classical statistics is proposed in this paper. The test is applicable in situations where the count data is uncertain, in the interval, or indeterminate, and it has been shown to be efficient in application and comparison studies.
SCIENTIFIC REPORTS
(2021)
Review
Microbiology
Wei Dang, Yan Xie, Pengfei Cao, Shuyu Xin, Jia Wang, Shen Li, Yanling Li, Jianhong Lu
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Virology
Wenxing Yue, Meijuan Zhu, Lielian Zuo, Shuyu Xin, Jing Zhang, Lingzhi Liu, Shen Li, Wei Dang, Siwei Zhang, Yan Xie, Fanxiu Zhu, Jianhong Lu
Article
Oncology
Lingzhi Liu, Lielian Zuo, Jing Yang, Shuyu Xin, Jing Zhang, Jianhua Zhou, Guiyuan Li, Jinyong Tang, Jianhong Lu
Review
Virology
Jing Zhang, Xiaohan Li, Jingjin Hu, Pengfei Cao, Qijia Yan, Siwei Zhang, Wei Dang, Jianhong Lu
Article
Multidisciplinary Sciences
Yu Li, Ziding Zhang, Li Yang, Xianyi Lian, Yan Xie, Shen Li, Shuyu Xin, Pengfei Cao, Jianhong Lu
Review
Microbiology
Jing Li, Shen Li, Li Yang, Pengfei Cao, Jianhong Lu
Summary: SFTSV is a novel bunyavirus that has been causing high fatality rates in China since 2007, with cases reported in other countries as well. The World Health Organisation has prioritized SFTSV for research and development in emergency contexts, but the pathogenesis of the virus remains largely unclear and there are currently no specific therapeutics available.
CRITICAL REVIEWS IN MICROBIOLOGY
(2021)
Article
Immunology
Xiang Zheng, Jia Wang, Xiaoyue Zhang, Yuxin Fu, Qiu Peng, Jianhong Lu, Lingyu Wei, Zhengshuo Li, Can Liu, Yangge Wu, Qun Yan, Jian Ma
Summary: This study provides mechanistic insights into the viral and cellular m(6)A epitranscriptomes during de novo EBV infection in the pre-latent phase. It reveals that EBV infection induces emergent and lost m(6)A modifications, and can influence the host cellular m(6)A epitranscriptome.
IMMUNITY INFLAMMATION AND DISEASE
(2021)
Review
Immunology
Xingyu Zhai, Yunfei Zhang, Shuyu Xin, Pengfei Cao, Jianhong Lu
Summary: Circular RNAs (circRNAs) are abundant, stable RNA molecules with circular structures that can serve as biomarkers for various diseases. In the context of autoimmune diseases (AIDs), circRNAs offer new possibilities for diagnosis and treatment by impacting the pathophysiological processes.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Oncology
Wei Dang, Pengfei Cao, Qijia Yan, Li Yang, Yiwei Wang, Jing Yang, Shuyu Xin, Jing Zhang, Jing Li, Sijing Long, Wentao Zhang, Senmiao Zhang, Jianhong Lu
Summary: This study reveals that EBV promotes tumorigenesis, particularly in B-cell lymphoma progression, by downregulating the novel p53-responsive lncRNA IGFBP7-AS1, which affects cell proliferation and apoptosis by regulating the stability of IGFBP7 mRNA and other related signaling pathways.
Review
Microbiology
Sijing Long, Li Yang, Wei Dang, Shuyu Xin, Mingjuan Jiang, Wentao Zhang, Jing Li, Yiwei Wang, Senmiao Zhang, Jianhong Lu
Summary: Deubiquitylating enzymes (DUBs) are proteases that reverse the fate of protein substrates by cracking the ubiquitin code, mediating cellular biological functions and antiviral innate immune response. They play a crucial role in fine-tuning antiviral immunity and may offer therapeutic opportunities for viral infections.
FRONTIERS IN MICROBIOLOGY
(2021)
Review
Cell Biology
Li Yang, Jing Li, Shen Li, Wei Dang, Shuyu Xin, Sijing Long, Wentao Zhang, Pengfei Cao, Jianhong Lu
Summary: Extracellular vesicles (EVs) serve as a tool for intercellular communication and are closely related to human health. Viruses can modulate their infection ability and pathogenicity by regulating the component and function of EVs, which in turn affects the occurrence and development of diseases.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Review
Virology
Yiwei Wang, Yanling Li, Xinyu Liang, Shuyu Xin, Li Yang, Pengfei Cao, Mingjuan Jiang, Yujie Xin, Senmiao Zhang, Yang Yang, Jianhong Lu
Summary: Cell-free DNA (cfDNA) is a popular cancer biomarker with advantages of being dynamic, instant, and noninvasive. This review summarizes the methods and techniques for detecting cfDNA from different body fluids, and discusses the implications of cfDNA derived from different tumor viruses in the detection and treatment monitoring of virus-associated cancers.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Correction
Microbiology
Yan Xie, Li Yang, Pengfei Cao, Shen Li, Wentao Zhang, Wei Dang, Shuyu Xin, Mingjuan Jiang, Yujie Xin, Jing Li, Sijing Long, Yiwei Wang, Senmiao Zhang, Yang Yang, Jianhong Lu
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Virology
Wentao Zhang, Yanling Li, Shuyu Xin, Li Yang, Mingjuan Jiang, Yujie Xin, Yiwei Wang, Pengfei Cao, Senmiao Zhang, Yang Yang, Jianhong Lu
Summary: IFIT3 is an important protein induced by interferon, playing a role in antiviral innate immunity and regulating cellular biology. It has the potential to serve as a biomarker for disease diagnosis and therapy.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Review
Oncology
Senmiao Zhang, Yanling Li, Shuyu Xin, Li Yang, Mingjuan Jiang, Yujie Xin, Yiwei Wang, Jing Yang, Jianhong Lu
Summary: This review summarizes the biological functions and clinical implications of long noncoding RNAs and circular RNAs as competitive endogenous RNAs in nasopharyngeal carcinoma (NPC). The imbalanced ceRNA networks derived from lncRNA/circRNA-miRNA-mRNA interaction are widely found to contribute to NPC development. Understanding the involvement of these ceRNAs networks provides new insights into the pathogenesis and treatment strategies of NPC.