Absent in melanoma 2 inflammasome is required for host defence against Streptococcus pneumoniae infection

Streptococcus pneumoniae: transmission, colonization and invasion

(2018) Jeffrey N. Weiser et al.   NATURE REVIEWS MICROBIOLOGY

Streptococcus pneumoniae’s Virulence and Host Immunity: Aging, Diagnostics, and Prevention

(2018) Lavida R. K. Brooks et al.   Frontiers in Immunology

AIM2 senses Brucella abortus DNA in dendritic cells to induce IL-1β secretion, pyroptosis and resistance to bacterial infection in mice

(2018) Miriam Maria Silva Costa Franco et al.   MICROBES AND INFECTION

IL-1R and Inflammasomes Mediate Early Pulmonary Protective Mechanisms in Respiratory Brucella Abortus Infection

(2018) M. Soledad Hielpos et al.   Frontiers in Cellular and Infection Microbiology

The AIM2 inflammasome: Sensor of pathogens and cellular perturbations

(2017) Jérôme Lugrin et al.   IMMUNOLOGICAL REVIEWS

Inflammasomes in the lung

(2017) James W. Pinkerton et al.   MOLECULAR IMMUNOLOGY

The IL-1 cytokine family and its role in inflammation and fibrosis in the lung

(2016) L. A. Borthwick   Seminars in Immunopathology

AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity

(2015) Si Ming Man et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Sensing of Interleukin-1 Cytokines during Streptococcus pneumoniae Colonization Contributes to Macrophage Recruitment and Bacterial Clearance

(2015) Jamie K. Lemon et al.   INFECTION AND IMMUNITY

Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt

(2015) Justin E Wilson et al.   NATURE MEDICINE

Inflammasome/IL-1β Responses to Streptococcal Pathogens

(2015) Christopher N. LaRock et al.   Frontiers in Immunology

NLRP3 and ASC Differentially Affect the Lung Transcriptome during Pneumococcal Pneumonia

(2013) Miriam H. van Lieshout et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Overview of Community-Acquired Pneumonia and the Role of Inflammatory Mechanisms in the Immunopathogenesis of Severe Pneumococcal Disease

(2013) Helen C. Steel et al.   MEDIATORS OF INFLAMMATION

Critical role of AIM2 in Mycobacterium tuberculosis infection

(2012) H. Saiga et al.   INTERNATIONAL IMMUNOLOGY

Interleukin-1 Promotes Coagulation, Which Is Necessary for Protective Immunity in the Lung Against Streptococcus pneumoniae Infection

(2012) Hyungjun Yang et al.   JOURNAL OF INFECTIOUS DISEASES

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Streptococcus pneumoniae Stimulates a STING- and IFN Regulatory Factor 3-Dependent Type I IFN Production in Macrophages, which Regulates RANTES Production in Macrophages, Cocultured Alveolar Epithelial Cells, and Mouse Lungs

(2011) U. Koppe et al.   JOURNAL OF IMMUNOLOGY

The NLRP3 Inflammasome Is Differentially Activated by Pneumolysin Variants and Contributes to Host Defense in Pneumococcal Pneumonia

(2011) M. Witzenrath et al.   JOURNAL OF IMMUNOLOGY

Critical Roles of ASC Inflammasomes in Caspase-1 Activation and Host Innate Resistance to Streptococcus pneumoniae Infection

(2011) R. Fang et al.   JOURNAL OF IMMUNOLOGY

Involvement of Absent in Melanoma 2 in Inflammasome Activation in Macrophages Infected with Listeria monocytogenes

(2010) K. Tsuchiya et al.   JOURNAL OF IMMUNOLOGY

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

(2010) Teresa Fernandes-Alnemri et al.   NATURE IMMUNOLOGY

Pneumolysin Activates the NLRP3 Inflammasome and Promotes Proinflammatory Cytokines Independently of TLR4

(2010) Edel A. McNeela et al.   PLoS Pathogens

Pathogenesis, treatment, and prevention of pneumococcal pneumonia

(2009) Tom van der Poll et al.   LANCET