Pneumolysin Activates the NLRP3 Inflammasome and Promotes Proinflammatory Cytokines Independently of TLR4

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense againstSalmonella

(2010) Petr Broz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-23 Receptor Regulates Unconventional IL-17–Producing T Cells That Control Bacterial Infections

(2010) Lorena Riol-Blanco et al.   JOURNAL OF IMMUNOLOGY

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals

(2009) Bruno Martin et al.   IMMUNITY

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

The roles of IL-17A in inflammatory immune responses and host defense against pathogens

(2009) Yoichiro Iwakura et al.   IMMUNOLOGICAL REVIEWS

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

(2009) Fiona A. Sharp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD4 T cells: fates, functions, and faults

(2008) J. Zhu et al.   BLOOD

Critical Involvement of Pneumolysin in Production of Interleukin-1  and Caspase-1-Dependent Cytokines in Infection with Streptococcus pneumoniae In Vitro: a Novel Function of Pneumolysin in Caspase-1 Activation

(2008) S. Shoma et al.   INFECTION AND IMMUNITY

Contribution of IL-1 to resistance to Streptococcus pneumoniae infection

(2008) D. Kafka et al.   INTERNATIONAL IMMUNOLOGY

Tumor Suppressor Cylindromatosis Acts as a Negative Regulator forStreptococcus pneumoniae-induced NFAT Signaling

(2008) Tomoaki Koga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Interleukin-17A Mediates Acquired Immunity to Pneumococcal Colonization

(2008) Ying-Jie Lu et al.   PLoS Pathogens