PinX1 represses renal cancer angiogenesis via the mir-125a-3p/VEGF signaling pathway

Consensus guidelines for the use and interpretation of angiogenesis assays

(2018) Patrycja Nowak-Sliwinska et al.   ANGIOGENESIS

miR-125a-3p is responsible for chemosensitivity in PDAC by inhibiting epithelial-mesenchymal transition via Fyn

(2018) Guodong Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

miR-125a-3p inhibits ERα transactivation and overrides tamoxifen resistance by targeting CDK3 in estrogen receptor–positive breast cancer

(2018) Lufeng Zheng et al.   FASEB JOURNAL

KIF4A facilitates cell proliferation via induction of p21-mediated cell cycle progression and promotes metastasis in colorectal cancer

(2018) Ping-Fu Hou et al.   Cell Death & Disease

Oncofoetal insulin receptor isoform A marks the tumour endothelium; an underestimated pathway during tumour angiogenesis and angiostatic treatment

(2018) Patrycja Nowak-Sliwinska et al.   BRITISH JOURNAL OF CANCER

The depletion of PinX1 involved in the tumorigenesis of non-small cell lung cancer promotes cell proliferation via p15/cyclin D1 pathway

(2017) Xiao-Peng Tian et al.   Molecular Cancer

miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway

(2017) Leilei Liang et al.   Cell Death & Disease

PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway

(2015) Meilin Shi et al.   Molecular Cancer

The telomere/telomerase binding factor PinX1 regulates paclitaxel sensitivity depending on spindle assembly checkpoint in human cervical squamous cell carcinomas

(2014) Xiao-Peng Tian et al.   CANCER LETTERS

The telomerase inhibitor Gno1p/PINX1 activates the helicase Prp43p during ribosome biogenesis

(2014) Y.-L. Chen et al.   NUCLEIC ACIDS RESEARCH

PinX1 suppresses bladder urothelial carcinoma cell proliferation via the inhibition of telomerase activity and p16/cyclin D1 pathway

(2013) Jian-Ye Liu et al.   Molecular Cancer

Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma

(2012) Michiel Smits et al.   FASEB JOURNAL

Ectopic Expression of MiR-125a Inhibits the Proliferation and Metastasis of Hepatocellular Carcinoma by Targeting MMP11 and VEGF

(2012) Qian Bi et al.   PLoS One

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

PinX1 the tail on the chromosome

(2011) F. Brad Johnson   JOURNAL OF CLINICAL INVESTIGATION

The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice

(2011) Xiao Zhen Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

(2011) Peter Carmeliet et al.   NATURE REVIEWS DRUG DISCOVERY

VEGF and angiopoietin signaling in tumor angiogenesis and metastasis

(2011) Pipsa Saharinen et al.   TRENDS IN MOLECULAR MEDICINE

Decreased expression of PinX1 protein is correlated with tumor development and is a new independent poor prognostic factor in ovarian carcinoma

(2010) Mu-Yan Cai et al.   CANCER SCIENCE

MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2

(2010) Linhui Liang et al.   HEPATOLOGY

MicroRNA-125b suppresses the development of bladder cancer by targeting E2F3

(2010) Li Huang et al.   INTERNATIONAL JOURNAL OF CANCER

MiR-125b targets BCL3 and suppresses ovarian cancer proliferation

(2010) Yi Guan et al.   INTERNATIONAL JOURNAL OF CANCER

Selective killing of Burkitt's lymphoma cells by mBAFF-targeted delivery of PinX1

(2010) L Zhang et al.   LEUKEMIA

Silencing PinX1 Compromises Telomere Length Maintenance As Well As Tumorigenicity in Telomerase-Positive Human Cancer Cells

(2008) B. Zhang et al.   CANCER RESEARCH