Oncofoetal insulin receptor isoform A marks the tumour endothelium; an underestimated pathway during tumour angiogenesis and angiostatic treatment

Consensus guidelines for the use and interpretation of angiogenesis assays

(2018) Patrycja Nowak-Sliwinska et al.   ANGIOGENESIS

High expression of insulin receptor on tumour-associated blood vessels in invasive bladder cancer predicts poor overall and progression-free survival

(2017) Filip Roudnicky et al.   JOURNAL OF PATHOLOGY

Insulin-like growth factor axis targeting in cancer and tumour angiogenesis - the missing link

(2016) Judy R. van Beijnum et al.   BIOLOGICAL REVIEWS

Role of the tumor stroma in resistance to anti-angiogenic therapy

(2016) Elisabeth J.M. Huijbers et al.   DRUG RESISTANCE UPDATES

Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis

(2015) Isabel Heidegger et al.   Oncotarget

The chicken chorioallantoic membrane model in biology, medicine and bioengineering

(2014) Patrycja Nowak-Sliwinska et al.   ANGIOGENESIS

A Phase I Study of Continuous Oral Dosing of OSI-906, a Dual Inhibitor of Insulin-Like Growth Factor-1 and Insulin Receptors, in Patients with Advanced Solid Tumors

(2014) I. Puzanov et al.   CLINICAL CANCER RESEARCH

Combination of the mTOR Inhibitor Ridaforolimus and the Anti-IGF1R Monoclonal Antibody Dalotuzumab: Preclinical Characterization and Phase I Clinical Trial

(2014) S. Di Cosimo et al.   CLINICAL CANCER RESEARCH

Endothelial cells and the IGF system

(2014) Leon A Bach   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF-1R) signaling systems: novel treatment strategies for cancer

(2013) Pushpendra Singh et al.   MEDICAL ONCOLOGY

Ensemble of Gene Signatures Identifies Novel Biomarkers in Colorectal Cancer Activated through PPARγ and TNFα Signaling

(2013) Stefano Maria Pagnotta et al.   PLoS One

Identification and Characterization of Angiogenesis Targets through Proteomic Profiling of Endothelial Cells in Human Cancer Tissues

(2013) Mehdi Mesri et al.   PLoS One

Targeting the insulin-like growth factor-1 receptor in human cancer

(2013) Alexandre Arcaro   Frontiers in Pharmacology

Rapid Angiogenesis Onset after Discontinuation of Sunitinib Treatment of Renal Cell Carcinoma Patients

(2012) A. W. Griffioen et al.   CLINICAL CANCER RESEARCH

Tumor angiogenesis is enforced by autocrine regulation of high-mobility group box 1

(2012) J R van Beijnum et al.   ONCOGENE

VEGF Inhibition, Hypertension, and Renal Toxicity

(2012) Suzanne R. Hayman et al.   Current Oncology Reports

Functional consequences of prolactin signalling in endothelial cells: a potential link with angiogenesis in pathophysiology?

(2011) Anne Q. Reuwer et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Organometallic Ruthenium(II) Arene Compounds with Antiangiogenic Activity

(2011) Patrycja Nowak-Sliwinska et al.   JOURNAL OF MEDICINAL CHEMISTRY

Potent Inhibition of Angiogenesis by the IGF-1 Receptor-Targeting Antibody SCH717454 Is Reversed by IGF-2

(2011) H. K. Bid et al.   MOLECULAR CANCER THERAPEUTICS

Vascular regrowth following photodynamic therapy in the chicken embryo chorioallantoic membrane

(2010) Patrycja Nowak-Sliwinska et al.   ANGIOGENESIS

Could recombinant insulin compounds contribute to adenocarcinoma progression by stimulating local angiogenesis?

(2010) K. L. Rensing et al.   DIABETOLOGIA

Randomized, Phase II Study of the Insulin-Like Growth Factor-1 Receptor Inhibitor IMC-A12, With or Without Cetuximab, in Patients With Cetuximab- or Panitumumab-Refractory Metastatic Colorectal Cancer

(2010) Diane Lauren Reidy et al.   JOURNAL OF CLINICAL ONCOLOGY

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Expression of Follicle-Stimulating Hormone Receptor in Tumor Blood Vessels

(2010) Aurelian Radu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of cancer cell proliferation and metastasis by insulin receptor downregulation

(2010) H Zhang et al.   ONCOGENE

The Neovessel Occlusion Efficacy of 151-Hydroxypurpurin-7-Lactone Dimethyl Ester Induced with Photodynamic Therapy

(2010) Siang Hui Lim et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer

(2009) R. N. Jorissen et al.   CLINICAL CANCER RESEARCH

Insulin glargine use and short-term incidence of malignancies—a population-based follow-up study in Sweden

(2009) J. M. Jonasson et al.   DIABETOLOGIA

Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: a cohort study

(2009) L. G. Hemkens et al.   DIABETOLOGIA

Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease

(2009) Antonino Belfiore et al.   ENDOCRINE REVIEWS

Sunitinib in solid tumors

(2009) Hui K Gan et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Cell and molecular mechanisms of insulin-induced angiogenesis

(2008) Yan Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Isolation of endothelial cells from fresh tissues

(2008) Judy R van Beijnum et al.   Nature Protocols

The role of insulin receptors and IGF-I receptors in cancer and other diseases

(2008) Francesco Frasca et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Angiogenic profiling and comparison of immortalized endothelial cells for functional genomics

(2007) Judy R. van Beijnum et al.   EXPERIMENTAL CELL RESEARCH