PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway

PinX1: a sought-after major tumor suppressor at human chromosome 8p23

(2015) Xiao Zhen Zhou   Oncotarget

Reduced expression of PinX1 correlates to progressive features in patients with prostate cancer

(2014) Rong Shi et al.   Cancer Cell International

Cullin1 is a novel marker of poor prognosis and a potential therapeutic target in human breast cancer

(2013) J. Bai et al.   ANNALS OF ONCOLOGY

PinX1 suppresses bladder urothelial carcinoma cell proliferation via the inhibition of telomerase activity and p16/cyclin D1 pathway

(2013) Jian-Ye Liu et al.   Molecular Cancer

HOXB13 downregulates intracellular zinc and increases NF-κB signaling to promote prostate cancer metastasis

(2013) Y-R Kim et al.   ONCOGENE

RUNX3 Suppresses Migration, Invasion and Angiogenesis of Human Renal Cell Carcinoma

(2013) Feifei Chen et al.   PLoS One

MLK3 Regulates Paxillin Phosphorylation in Chemokine-Mediated Breast Cancer Cell Migration and Invasion to Drive Metastasis

(2012) Jian Chen et al.   CANCER RESEARCH

BRG1 expression is increased in human glioma and controls glioma cell proliferation, migration and invasion in vitro

(2012) Jin Bai et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

PinX1 regulation of telomerase activity and apoptosis in nasopharyngeal carcinoma cells

(2012) Xiao-Fen Lai et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Breast cancer risk–associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression

(2012) Richard Cowper-Sal·lari et al.   NATURE GENETICS

Suppression of matrix metalloproteinase-9 expression by andrographolide in human monocytic THP-1 cells via inhibition of NF-κB activation

(2012) Woan-Ruoh Lee et al.   PHYTOMEDICINE

Breast cancer statistics, 2011

(2011) Carol DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice

(2011) Xiao Zhen Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop

(2011) Lili Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Decreased expression of PinX1 protein is correlated with tumor development and is a new independent poor prognostic factor in ovarian carcinoma

(2010) Mu-Yan Cai et al.   CANCER SCIENCE

α-Mangostin Suppresses Phorbol 12-myristate 13-acetate-Induced MMP-2/MMP-9 Expressions via αvβ3 Integrin/FAK/ERK and NF-κB Signaling Pathway in Human Lung Adenocarcinoma A549 Cells

(2010) Yuan-Wei Shih et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Overexpression of Cullin1 is associated with poor prognosis of patients with gastric cancer☆

(2010) Jin Bai et al.   HUMAN PATHOLOGY

Selective killing of Burkitt's lymphoma cells by mBAFF-targeted delivery of PinX1

(2010) L Zhang et al.   LEUKEMIA

KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9

(2010) X Wang et al.   ONCOGENE

JWA regulates melanoma metastasis by integrin αVβ3 signaling

(2009) J Bai et al.   ONCOGENE

Silencing PinX1 Compromises Telomere Length Maintenance As Well As Tumorigenicity in Telomerase-Positive Human Cancer Cells

(2008) B. Zhang et al.   CANCER RESEARCH

NF-κB and cancer—identifying targets and mechanisms

(2008) Willscott E Naugler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The correlation of genetic instability of PINX1 gene to clinico-pathological features of gastric cancer in the Chinese population

(2008) Yingyu Ma et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance

(2008) Tae Ho Lee et al.   NATURE CELL BIOLOGY