PinX1 the tail on the chromosome

The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice

(2011) Xiao Zhen Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction

(2010) Olga A. Kovalenko et al.   AGING CELL

Senescent cells as a source of inflammatory factors for tumor progression

(2010) Albert R. Davalos et al.   CANCER AND METASTASIS REVIEWS

Telomerase Inhibitor PinX1 Provides a Link between TRF1 and Telomerase to Prevent Telomere Elongation

(2010) Christina Y. Soohoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Telomeres and telomerase in cancer

(2009) S. E. Artandi et al.   CARCINOGENESIS

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

(2009) Agnel Sfeir et al.   CELL

PinX1 Is a Novel Microtubule-binding Protein Essential for Accurate Chromosome Segregation

(2009) Kai Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human PinX1 Mediates TRF1 Accumulation in Nucleolus and Enhances TRF1 Binding to Telomeres

(2009) Jeong Eun Yoo et al.   JOURNAL OF MOLECULAR BIOLOGY

Telomerase modulates Wnt signalling by association with target gene chromatin

(2009) Jae-Il Park et al.   NATURE

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

Telomerase-dependent and -independent chromosome healing in mouse embryonic stem cells

(2008) Qing Gao et al.   DNA REPAIR