Obeticholic acid ameliorates dyslipidemia but not glucose tolerance in a mouse model of gestational diabetes

Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration

(2017) Gloria Alvarez-Sola et al.   GUT

Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism

(2017) Preeti Pathak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential regulation of intestinal efflux transporters by pregnancy in mice

(2017) Jamie E. Moscovitz et al.   XENOBIOTICA

Association of History of Gestational Diabetes With Long-term Cardiovascular Disease Risk in a Large Prospective Cohort of US Women

(2017) Deirdre K. Tobias et al.   JAMA Internal Medicine

Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

(2016) Annika Wahlström et al.   Cell Metabolism

Farnesoid X receptor activation increases reverse cholesterol transport by modulating bile acid composition and cholesterol absorption in mice

(2016) Yang Xu et al.   HEPATOLOGY

Regulation of lipid metabolism by obeticholic acid in hyperlipidemic hamsters

(2016) Bin Dong et al.   JOURNAL OF LIPID RESEARCH

Restoration of enterohepatic bile acid pathways in pregnant mice following short term activation of Fxr by GW4064

(2016) Jamie E. Moscovitz et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Maternal Obesity Promotes Diabetic Nephropathy in Rodent Offspring

(2016) Sarah J. Glastras et al.   Scientific Reports

Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells

(2015) Mohamed-Sami Trabelsi et al.   Nature Communications

Metabolic fingerprint of Gestational Diabetes Mellitus

(2014) Danuta Dudzik et al.   Journal of Proteomics

Serum Concentrations of Fibroblast Growth Factors 19 and 21 in Women with Gestational Diabetes Mellitus: Association with Insulin Resistance, Adiponectin, and Polycystic Ovary Syndrome History

(2013) Dongyu Wang et al.   PLoS One

Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype

(2012) Shadi Abu-Hayyeh et al.   HEPATOLOGY

Gestational Diabetes and the Offspring: Implications in the Development of the Cardiorenal Metabolic Syndrome in Offspring

(2012) Liliana Garcia-Vargas et al.   CardioRenal Medicine

Implication of Low Level Inflammation in the Insulin Resistance of Adipose Tissue at Late Pregnancy

(2011) J. de Castro et al.   ENDOCRINOLOGY

Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2 −/− (Abcb4 −/− ) mouse cholangiopathy model by promoting biliary HCO 3− output

(2011) Anna Baghdasaryan et al.   HEPATOLOGY

Microbial Community Development in a Dynamic Gut Model Is Reproducible, Colon Region Specific, and Selective for Bacteroidetes and Clostridium Cluster IX

(2010) P. Van den Abbeele et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Farnesoid X Receptor Activation Improves Erectile Function in Animal Models of Metabolic Syndrome and Diabetes

(2010) Linda Vignozzi et al.   Journal of Sexual Medicine

Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis

(2009) Leanne Bellamy et al.   LANCET

High–saturated-fat diet induces gestational diabetes and placental vasculopathy in C57BL/6 mice

(2009) Chengya Liang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice

(2008) Nicole JW de Wit et al.   BMC Medical Genomics

Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response

(2008) Yan-Dong Wang et al.   HEPATOLOGY

Comparison of oritavancin versus vancomycin as treatments for clindamycin-induced Clostridium difficile PCR ribotype 027 infection in a human gut model

(2008) S. D. Baines et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Hyperglycemia and Adverse Pregnancy Outcomes

(2008)   NEW ENGLAND JOURNAL OF MEDICINE