Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

(2015) Sungsoon Fang et al.   NATURE MEDICINE

Nuclear bile acid signaling through the farnesoid X receptor

(2014) Claire Mazuy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular Mechanisms of Glucose-Stimulated GLP-1 Secretion From Perfused Rat Small Intestine

(2014) Rune E. Kuhre et al.   DIABETES

Loss ofCyp8b1Improves Glucose Homeostasis by Increasing GLP-1

(2014) Achint Kaur et al.   DIABETES

FXR is a molecular target for the effects of vertical sleeve gastrectomy

(2014) Karen K. Ryan et al.   NATURE

Beyond intestinal soap—bile acids in metabolic control

(2014) Folkert Kuipers et al.   Nature Reviews Endocrinology

Glucose-lowering effects of intestinal bile acid sequestration through enhancement of splanchnic glucose utilization

(2014) Janne Prawitt et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Microbial Modulation of Energy Availability in the Colon Regulates Intestinal Transit

(2013) Anita Wichmann et al.   Cell Host & Microbe

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Glucose sensing O-GlcNAcylation pathway regulates the nuclear bile acid receptor farnesoid X receptor (FXR)

(2013) Wahiba Berrabah et al.   HEPATOLOGY

Farnesoid X Receptor Inhibits the Transcriptional Activity of Carbohydrate Response Element Binding Protein in Human Hepatocytes

(2013) S. Caron et al.   MOLECULAR AND CELLULAR BIOLOGY

Ageing Fxr Deficient Mice Develop Increased Energy Expenditure, Improved Glucose Control and Liver Damage Resembling NASH

(2013) Mikael Bjursell et al.   PLoS One

Novel insights into ChREBP regulation and function

(2013) Gaëlle Filhoulaud et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery

(2012) Maartje C. P. Geraedts et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice

(2012) Matthew J. Potthoff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion

(2012) H. E. Parker et al.   DIABETOLOGIA

Overlap of Endocrine Hormone Expression in the Mouse Intestine Revealed by Transcriptional Profiling and Flow Cytometry

(2012) Abdella M. Habib et al.   ENDOCRINOLOGY

Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease

(2012) Geoffrey Porez et al.   JOURNAL OF LIPID RESEARCH

The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine

(2012) Oliver J. Mace et al.   JOURNAL OF PHYSIOLOGY-LONDON

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins

(2012) Taoufiq Harach et al.   Scientific Reports

Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity

(2011) J. Prawitt et al.   DIABETES

PPARβ/δ Activation Induces Enteroendocrine L Cell GLP-1 Production

(2011) Mehdi Daoudi et al.   GASTROENTEROLOGY

Lowering Bile Acid Pool Size with a Synthetic Farnesoid X Receptor (FXR) Agonist Induces Obesity and Diabetes through Reduced Energy Expenditure

(2011) Mitsuhiro Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bile Acid Sequestration Reduces Plasma Glucose Levels in db/db Mice by Increasing Its Metabolic Clearance Rate

(2011) Maxi Meissner et al.   PLoS One

Intestinal FXR-mediated FGF15 production contributes to diurnal control of hepatic bile acid synthesis in mice

(2010) Johanna H M Stroeve et al.   LABORATORY INVESTIGATION

Bile Acid Sequestrants: Glucose-Lowering Mechanisms

(2010) Janne Prawitt et al.   Metabolic Syndrome and Related Disorders

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Colesevelam lowers glucose and lipid levels in type 2 diabetes: the clinical evidence

(2009) Vivian A. Fonseca et al.   DIABETES OBESITY & METABOLISM

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

Glucose Sensing in L Cells: A Primary Cell Study

(2008) Frank Reimann et al.   Cell Metabolism