Plant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages

Regulation of the Cell Biology of Antigen Cross-Presentation

(2018) J. Magarian Blander   Annual Review of Immunology

Identification of immunodominant CD8 epitope in the stalk domain of influenza B viral hemagglutinin

(2018) Abenaya Muralidharan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intramuscular and intranasal immunization with an H7N9 influenza virus-like particle vaccine protects mice against lethal influenza virus challenge

(2018) Zhiguang Ren et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Combining stable insect cell lines with baculovirus-mediated expression for multi-HA influenza VLP production

(2018) Daniela P. Sequeira et al.   VACCINE

Morphological characterization of a plant-made virus-like particle vaccine bearing influenza virus hemagglutinins by electron microscopy

(2018) Brianne J. Lindsay et al.   VACCINE

Immune responses after live attenuated influenza vaccination

(2018) Kristin G.-I. Mohn et al.   Human Vaccines & Immunotherapeutics

The CD8 T Cell Response to Respiratory Virus Infections

(2018) Megan E. Schmidt et al.   Frontiers in Immunology

Humoral and cell-mediated immune responses to H5N1 plant-made virus-like particle vaccine are differentially impacted by alum and GLA-SE adjuvants in a Phase 2 clinical trial

(2018) Stéphane Pillet et al.   npj Vaccines

Characterization of the innate stimulatory capacity of plant-derived virus-like particles bearing influenza hemagglutinin

(2018) So-Yoon Won et al.   VACCINE

Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2

(2017) Jil Sander et al.   IMMUNITY

Lineage-specific epitope profiles for HPAI H5 pre-pandemic vaccine selection and evaluation

(2017) Xueting Qiu et al.   Influenza and Other Respiratory Viruses

The molecular basis for peptide repertoire selection in the human leukocyte antigen (HLA) C*06:02 molecule

(2017) Jesse I. Mobbs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plant-made virus-like particles bearing influenza hemagglutinin (HA) recapitulate early interactions of native influenza virions with human monocytes/macrophages

(2017) Alexander I. Makarkov et al.   VACCINE

Plant-made virus-like particle vaccines bearing the hemagglutinin of either seasonal (H1) or avian (H5) influenza have distinct patterns of interaction with human immune cells in vitro

(2017) Hilary E. Hendin et al.   VACCINE

Synthetic plant virology for nanobiotechnology and nanomedicine

(2017) John F. C. Steele et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice

(2017) Wenqian He et al.   Nature Communications

Escherichia coli-derived virus-like particles in vaccine development

(2017) Xiaofen Huang et al.   npj Vaccines

Comparisons of the Humoral and Cellular Immune Responses Induced by Live Attenuated Influenza Vaccine and Inactivated Influenza Vaccine in Adults

(2016) Daniel F. Hoft et al.   Clinical and Vaccine Immunology

A plant-derived quadrivalent virus like particle influenza vaccine induces cross-reactive antibody and T cell response in healthy adults

(2016) Stéphane Pillet et al.   CLINICAL IMMUNOLOGY

Molecular pharming — VLPs made in plants

(2016) Johanna Marsian et al.   CURRENT OPINION IN BIOTECHNOLOGY

The contributions of lung macrophage and monocyte heterogeneity to influenza pathogenesis

(2016) Mubing Duan et al.   IMMUNOLOGY AND CELL BIOLOGY

Identification of MHC-Bound Peptides from Dendritic Cells Infected with Salmonella enterica Strain SL1344: Implications for a Nontyphoidal Salmonella Vaccine

(2016) Karuna P. Karunakaran et al.   JOURNAL OF PROTEOME RESEARCH

Human influenza viruses and CD8 + T cell responses

(2016) Emma J Grant et al.   Current Opinion in Virology

Heterosubtypic T-Cell Immunity to Influenza in Humans: Challenges for Universal T-Cell Influenza Vaccines

(2016) Saranya Sridhar   Frontiers in Immunology

Virus like particle-based vaccines against emerging infectious disease viruses

(2016) Jinliang Liu et al.   VIROLOGICA SINICA

The application of virus-like particles as vaccines and biological vehicles

(2015) Dan Yan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The Impact II, a Very High-Resolution Quadrupole Time-of-Flight Instrument (QTOF) for Deep Shotgun Proteomics

(2015) Scarlet Beck et al.   MOLECULAR & CELLULAR PROTEOMICS

Analysis of Major Histocompatibility Complex (MHC) Immunopeptidomes Using Mass Spectrometry

(2015) Etienne Caron et al.   MOLECULAR & CELLULAR PROTEOMICS

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Physical detection of influenza A epitopes identifies a stealth subset on human lung epithelium evading natural CD8 immunity

(2015) Derin B. Keskin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ISCOMATRIX™ adjuvant promotes epitope spreading and antibody affinity maturation of influenza A H7N9 virus like particle vaccine that correlate with virus neutralization in humans

(2015) Ka Yan Chung et al.   VACCINE

Incorporation of conserved nucleoprotein into influenza virus-like particles could provoke a broad protective immune response in BALB/c mice and chickens

(2015) Chunyi Xue et al.   VIRUS RESEARCH

A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus

(2015) Ying Wu et al.   Nature Communications

Heat shock protein 90 targets a chaperoned peptide to the static early endosome for efficient cross-presentation by human dendritic cells

(2014) Tsutomu Tanaka et al.   CANCER SCIENCE

TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation

(2014) Priyanka Nair-Gupta et al.   CELL

Influenza virus-like particle vaccines made in Nicotiana benthamiana elicit durable, poly-functional and cross-reactive T cell responses to influenza HA antigens

(2014) Nathalie Landry et al.   CLINICAL IMMUNOLOGY

Redirecting soluble antigen for MHC class I cross-presentation during phagocytosis

(2014) Aswin Hari et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Virus-like particles as antigenic nanomaterials for inducing protective immune responses in the lung

(2014) Agnieszka Rynda-Apple et al.   Nanomedicine

Biochemical composition of haemagglutinin-based influenza virus-like particle vaccine produced by transient expression in tobacco plants

(2014) François Le Mauff et al.   PLANT BIOTECHNOLOGY JOURNAL

Endosome maturation, transport and functions

(2014) Cameron C. Scott et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: Results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers

(2014) Jenny G.H. Low et al.   VACCINE

The Complex Ultrastructure of the Endolysosomal System

(2014) J. Klumperman et al.   Cold Spring Harbor Perspectives in Biology

Function and Regulation of the Endosomal Fusion and Fission Machineries

(2014) A. Gautreau et al.   Cold Spring Harbor Perspectives in Biology

Immunogenicity of H1N1 influenza virus-like particles produced inNicotiana benthamiana

(2014) Yoko Shoji et al.   Human Vaccines & Immunotherapeutics

Enhanced Influenza VLP vaccines comprising matrix-2 ectodomain and nucleoprotein epitopes protects mice from lethal challenge

(2013) Xiao Gao et al.   ANTIVIRAL RESEARCH

Virus-like particles: the future of microbial factories and cell-free systems as platforms for vaccine development

(2013) William A Rodríguez-Limas et al.   CURRENT OPINION IN BIOTECHNOLOGY

Virus-like particles produced in plants as potential vaccines

(2013) Nunzia Scotti et al.   Expert Review of Vaccines

Protective CD8 T Cell-Mediated Immunity against Influenza A Virus Infection following Influenza Virus-like Particle Vaccination

(2013) E. A. Hemann et al.   JOURNAL OF IMMUNOLOGY

Longitudinal and Integrative Biomodeling of Effector and Memory Immune Compartments after Inactivated Influenza Vaccination

(2013) O. Bonduelle et al.   JOURNAL OF IMMUNOLOGY

Pattern of activation of human antigen presenting cells by genotype GII.4 norovirus virus-like particles

(2013) Eleonora Ponterio et al.   Journal of Translational Medicine

Hepatitis B virus-like particles access major histocompatibility class I and II antigen presentation pathways in primary dendritic cells

(2013) Jessica M. Moffat et al.   VACCINE

Safety and immunogenicity of a plant-produced recombinant monomer hemagglutinin-based influenza vaccine derived from influenza A (H1N1)pdm09 virus: A Phase 1 dose-escalation study in healthy adults

(2013) James F. Cummings et al.   VACCINE

MHC Class II Antigen Presentation by Dendritic Cells Regulated through Endosomal Sorting

(2013) T. ten Broeke et al.   Cold Spring Harbor Perspectives in Biology

Virus-like particles as universal influenza vaccines

(2012) Sang-Moo Kang et al.   Expert Review of Vaccines

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

(2012) Tom M Wilkinson et al.   NATURE MEDICINE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Production and characterization of mammalian virus-like particles from modified vaccinia virus Ankara vectors expressing influenza H5N1 hemagglutinin and neuraminidase

(2012) Falko Schmeisser et al.   VACCINE

Plant-derived virus-like particles as vaccines

(2012) Qiang Chen et al.   Human Vaccines & Immunotherapeutics

The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza

(2010) Marc-André D’Aoust et al.   PLANT BIOTECHNOLOGY JOURNAL

Mammalian Expression of Virus-Like Particles for Advanced Mimicry of Authentic Influenza Virus

(2010) Chia-Ying Wu et al.   PLoS One

In vitro stimulation of human influenza-specific CD8+ T cells by dendritic cells pulsed with an influenza virus-like particle (VLP) vaccine

(2010) Haifeng Song et al.   VACCINE

HLA class I molecules consistently present internal influenza epitopes

(2009) A. Wahl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IRAP Identifies an Endosomal Compartment Required for MHC Class I Cross-Presentation

(2009) L. Saveanu et al.   SCIENCE

Endocytosis mechanisms and the cell biology of antigen presentation

(2008) Sven Burgdorf et al.   CURRENT OPINION IN IMMUNOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Influenza virus-like particles produced by transient expression inNicotiana benthamianainduce a protective immune response against a lethal viral challenge in mice

(2008) Marc-André D’Aoust et al.   PLANT BIOTECHNOLOGY JOURNAL