Sjogren’s Syndrome and TAM Receptors: A Possible Contribution to Disease Onset

Impaired anti-inflammatory activity of PPARγ in the salivary epithelia of Sjögren's syndrome patients imposed by intrinsic NF-κB activation

(2018) Aigli G. Vakrakou et al.   JOURNAL OF AUTOIMMUNITY

Clinical and immunological parameters of Sjögren's syndrome

(2018) Konstantia Psianou et al.   AUTOIMMUNITY REVIEWS

Efferocytosis and autoimmune disease

(2018) Mahiru Kawano et al.   INTERNATIONAL IMMUNOLOGY

Macrophages in inflammation, repair and regeneration

(2018) Yumiko Oishi et al.   INTERNATIONAL IMMUNOLOGY

Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution

(2018) Jonathan D. Proto et al.   IMMUNITY

The Dual Role of TAM Receptors in Autoimmune Diseases and Cancer: An Overview

(2018) Martha Wium et al.   Cells

Myd88 is required for disease development in a primary Sjögren’s syndrome mouse model

(2017) Jeremy Kiripolsky et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Phosphatidylserine Is the Signal for TAM Receptors and Their Ligands

(2017) Greg Lemke   TRENDS IN BIOCHEMICAL SCIENCES

Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses

(2017) Laurent Meertens et al.   Cell Reports

Requirement of Gamma-Carboxyglutamic Acid Modification and Phosphatidylserine Binding for the Activation of Tyro3, Axl, and Mertk Receptors by Growth Arrest-Specific 6

(2017) Ke Geng et al.   Frontiers in Immunology

The Dynamics of Apoptotic Cell Clearance

(2016) Michael R. Elliott et al.   DEVELOPMENTAL CELL

Age-related spontaneous lacrimal keratoconjunctivitis is accompanied by dysfunctional T regulatory cells

(2016) T G Coursey et al.   Mucosal Immunology

Sexual dimorphic function of IL-17 in salivary gland dysfunction of the C57BL/6.NOD-Aec1Aec2 model of Sjögren’s syndrome

(2016) Alexandria Voigt et al.   Scientific Reports

2016 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Primary Sjögren's Syndrome: A Consensus and Data-Driven Methodology Involving Three International Patient Cohorts

(2016) Caroline H. Shiboski et al.   Arthritis & Rheumatology

TAM Receptor Signaling in Immune Homeostasis

(2015) Carla V. Rothlin et al.   Annual Review of Immunology

Toll-Like Receptor Pathways in Autoimmune Diseases

(2015) Ji-Qing Chen et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Swallowing Disorders in Sjögren’s Syndrome: Prevalence, Risk Factors, and Effects on Quality of Life

(2015) Jenny L. Pierce et al.   DYSPHAGIA

Clinical and laboratory profiles of primary Sjogren's syndrome in a Chinese population: A retrospective analysis of 315 patients

(2015) Xiaomei Li et al.   International Journal of Rheumatic Diseases

The association of Tyro3/Axl/Mer signaling with inflammatory response, disease activity in patients with primary Sjögren's syndrome

(2015) Baodong Qin et al.   JOINT BONE SPINE

Type I and II interferon signatures in Sjogren's syndrome pathogenesis: Contributions in distinct clinical phenotypes and Sjogren's related lymphomagenesis

(2015) Adrianos Nezos et al.   JOURNAL OF AUTOIMMUNITY

Quality of Sexual Life in Women with Primary Sjogren Syndrome

(2015) R. Priori et al.   JOURNAL OF RHEUMATOLOGY

T Regulatory and T Helper 17 Cells in Primary Sjögren’s Syndrome: Facts and Perspectives

(2015) Alessia Alunno et al.   MEDIATORS OF INFLAMMATION

Phagocytosis of apoptotic cells in homeostasis

(2015) Sanja Arandjelovic et al.   NATURE IMMUNOLOGY

Renal involvement in primary Sjögren syndrome

(2015) Hélène François et al.   Nature Reviews Nephrology

Ocular and Systemic Morbidity in a Longitudinal Cohort of Sjögren’s Syndrome

(2015) Esen Karamursel Akpek et al.   OPHTHALMOLOGY

Increased soluble phagocytic receptors sMer, sTyro3 and sAxl and reduced phagocytosis in Juvenile-onset Systemic Lupus Erythematosus

(2015) Lucy Ballantine et al.   Pediatric Rheumatology

Renal involvement in primary Sjögren’s syndrome

(2015) Rhys Evans et al.   RHEUMATOLOGY

The impact of primary Sjögren’s syndrome on female sexual function

(2015) Jolien F. van Nimwegen et al.   RHEUMATOLOGY

The clinical relevance of animal models in Sjögren’s syndrome: the interferon signature from mouse to man

(2015) Naomi I Maria et al.   ARTHRITIS RESEARCH & THERAPY

Growth Arrest-Specific 6 Protein in Patients with Sjögren Syndrome: Determination of the Plasma Level and Expression in the Labial Salivary Gland

(2015) Chen-Hung Chen et al.   PLoS One

Epidemiology of primary Sjögren's syndrome: a systematic review and meta-analysis

(2014) Baodong Qin et al.   ANNALS OF THE RHEUMATIC DISEASES

TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis

(2014) J. H. M. van der Meer et al.   BLOOD

Dysregulation of the suppressor of cytokine signalling 3-signal transducer and activator of transcription-3 pathway in the aetiopathogenesis of Sjögren's syndrome

(2014) S. R. Vartoukian et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Monocytes from Sjögren's syndrome patients display increased vasoactive intestinal peptide receptor 2 expression and impaired apoptotic cell phagocytosis

(2014) V. Hauk et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

Diversification of TAM receptor tyrosine kinase function

(2014) Anna Zagórska et al.   NATURE IMMUNOLOGY

Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities

(2014) Erin D Lew et al.   eLife

SOCS3, a Major Regulator of Infection and Inflammation

(2014) Berit Carow et al.   Frontiers in Immunology

An estimation of the number of cells in the human body

(2013) Eva Bianconi et al.   ANNALS OF HUMAN BIOLOGY

MxA as a clinically applicable biomarker for identifying systemic interferon type I in primary Sjögren's syndrome

(2013) Naomi I Maria et al.   ANNALS OF THE RHEUMATIC DISEASES

Enveloped Viruses Disable Innate Immune Responses in Dendritic Cells by Direct Activation of TAM Receptors

(2013) Suchita Bhattacharyya et al.   Cell Host & Microbe

Enhanced Apoptosis by Disruption of the STAT3-IκB-ζ Signaling Pathway in Epithelial Cells Induces Sjögren’s Syndrome-like Autoimmune Disease

(2013) Atsushi Okuma et al.   IMMUNITY

CXCL13 is elevated in Sjögrenˈs syndrome in mice and humans and is implicated in disease pathogenesis

(2013) Jill M. Kramer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The inhibitory effects of antimuscarinic autoantibodies in the sera of primary Sjogren syndrome patients on the gastrointestinal motility

(2013) Kyungpyo Park et al.   MOLECULAR IMMUNOLOGY

Transcriptional landscapes of emerging autoimmunity: transient aberrations in the targeted tissue’s extracellular milieu precede immune responses in Sjögren’s syndrome

(2013) Nicolas Delaleu et al.   ARTHRITIS RESEARCH & THERAPY

Vitamin K-dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity

(2013) Pedro Recarte-Pelz et al.   ARTHRITIS RESEARCH & THERAPY

Circulating levels of soluble MER in lupus reflect M2c activation of monocytes/macrophages, autoantibody specificities and disease activity

(2013) Gaetano Zizzo et al.   ARTHRITIS RESEARCH & THERAPY

Biology of the TAM Receptors

(2013) G. Lemke   Cold Spring Harbor Perspectives in Biology

Oral Complications of Sjögren's Syndrome

(2013) Joel J. Napeñas et al.   Oral and Maxillofacial Surgery Clinics of North America

Sjögren's Syndrome

(2013) Tove R. Reksten et al.   Oral and Maxillofacial Surgery Clinics of North America

Prevalence of interferon type I signature in CD14 monocytes of patients with Sjögren's syndrome and association with disease activity and BAFF gene expression

(2012) Zana Brkic et al.   ANNALS OF THE RHEUMATIC DISEASES

The biology and mechanism of action of suppressor of cytokine signaling 3

(2012) Jeffrey J. Babon et al.   GROWTH FACTORS

Plasma concentrations of growth arrest specific protein 6 and the soluble form of its tyrosine kinase receptor Axl in patients with Systemic lupus erythematosus and Behçets disease

(2012) Tamer A. Gheita et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Salivary gland hypofunction induced by activation of innate immunity is dependent on type I interferon signaling

(2012) Seshagiri-Rao Nandula et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

Transcriptome Analysis of the Interferon-Signature Defining the Autoimmune Process of Sjögren’s Syndrome

(2012) A. B. Peck et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Primary Sjögren's syndrome as a systemic disease: A study of participants enrolled in an International Sjögren's syndrome registry

(2012) Arundathi S. Malladi et al.   ARTHRITIS CARE & RESEARCH

Overview of the biology of type I interferons

(2012) George D Kalliolias et al.   ARTHRITIS RESEARCH & THERAPY

SOCS, Inflammation, and Autoimmunity

(2012) Akihiko Yoshimura et al.   Frontiers in Immunology

Evaluation of gastrointestinal symptoms in different patient groups using the visual analogue scale for irritable bowel syndrome (VAS-IBS)

(2011) Mariette Bengtsson et al.   BMC GASTROENTEROLOGY

The Soluble Serum Protein Gas6 Bridges Virion Envelope Phosphatidylserine to the TAM Receptor Tyrosine Kinase Axl to Mediate Viral Entry

(2011) Kouki Morizono et al.   Cell Host & Microbe

Gastrointestinal and Hepatic Manifestations of Sjogren Syndrome

(2011) Ellen Catherine Ebert   JOURNAL OF CLINICAL GASTROENTEROLOGY

Prognosis and Outcome of Non-Hodgkin Lymphoma in Primary Sjögren Syndrome

(2011) Michael Voulgarelis et al.   MEDICINE

Temporal changes in salivary glands of non-obese diabetic mice as a model for Sjögren’s syndrome

(2011) N Roescher et al.   ORAL DISEASES

Sjögren's syndrome: studying the disease in mice

(2011) Nicolas Delaleu et al.   ARTHRITIS RESEARCH & THERAPY

TAM receptors and the clearance of apoptotic cells

(2010) Greg Lemke et al.   Annals of the New York Academy of Sciences

TAM receptor signaling and autoimmune disease

(2010) Carla V Rothlin et al.   CURRENT OPINION IN IMMUNOLOGY

Salivary epithelial cells from Sjogren’s syndrome patients are highly sensitive to anoikis induced by TLR-3 ligation

(2010) Menelaos N. Manoussakis et al.   JOURNAL OF AUTOIMMUNITY

Activation of the type I interferon pathway in primary Sjogren’s syndrome

(2010) Clio P. Mavragani et al.   JOURNAL OF AUTOIMMUNITY

Articular manifestations in primary Sjogren's syndrome: clinical significance and prognosis of 188 patients

(2010) A. L. Fauchais et al.   RHEUMATOLOGY

TAM receptor ligands in lupus: Protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosus

(2010) Chang-Hee Suh et al.   ARTHRITIS RESEARCH & THERAPY

Characteristics of the minor salivary gland infiltrates in Sjögren's syndrome

(2009) Maria I. Christodoulou et al.   JOURNAL OF AUTOIMMUNITY

The SOCS Box Encodes a Hierarchy of Affinities for Cullin5: Implications for Ubiquitin Ligase Formation and Cytokine Signalling Suppression

(2009) Jeffrey J. Babon et al.   JOURNAL OF MOLECULAR BIOLOGY

Secondary necrosis in multicellular animals: an outcome of apoptosis with pathogenic implications

(2008) Manuel T. Silva et al.   APOPTOSIS

Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: a pooled analysis within the InterLymph Consortium

(2008) K. Ekstrom Smedby et al.   BLOOD

Putting out the fire: coordinated suppression of the innate and adaptive immune systems by SOCS1 and SOCS3 proteins

(2008) Ioannis D. Dimitriou et al.   IMMUNOLOGICAL REVIEWS

Pulmonary Manifestations of Primary Sjögren's Syndrome

(2008) Ann L. Parke   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA