Dysregulation of the suppressor of cytokine signalling 3-signal transducer and activator of transcription-3 pathway in the aetiopathogenesis of Sjögren's syndrome

Th17 cells play a critical role in the development of experimental Sjögren's syndrome

(2014) Xiang Lin et al.   ANNALS OF THE RHEUMATIC DISEASES

Identification of IL-18 and Th17 Cells in Salivary Glands of Patients with Sjogren's Syndrome, and Amplification of IL-17-Mediated Secretion of Inflammatory Cytokines from Salivary Gland Cells by IL-18

(2014) A. Sakai et al.   JOURNAL OF IMMUNOLOGY

Janus kinase inhibitors in autoimmune diseases

(2013) John J O'Shea et al.   ANNALS OF THE RHEUMATIC DISEASES

Overexpression of SOCS3 in T Lymphocytes Leads to Impaired Interleukin-17 Production and Severe Aortic Aneurysm Formation in Mice—Brief Report

(2013) Mélissa Romain et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

SOCS3 Transactivation by PPAR  Prevents IL-17-Driven Cancer Growth

(2013) H. Berger et al.   CANCER RESEARCH

Hydroxychloroquine decreases Th17-related cytokines in systemic lupus erythematosus and rheumatoid arthritis patients

(2013) JC Silva et al.   Clinics

Parasite Infections in Multiple Sclerosis Modulate Immune Responses through a Retinoic Acid-Dependent Pathway

(2013) J. Correale et al.   JOURNAL OF IMMUNOLOGY

SOCS3 Expression Correlates with Severity of Inflammation, Expression of Proinflammatory Cytokines, and Activation of STAT3 and p38 MAPK in LPS-Induced InflammationIn Vivo

(2013) João Antônio Chaves de Souza et al.   MEDIATORS OF INFLAMMATION

SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition

(2013) Nadia J Kershaw et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Suppressive Oligodeoxynucleotides Promote the Development of Th17 Cells

(2013) Christian Bode et al.   PLoS One

SOCS3 promotes interleukin-17 expression of human T cells

(2012) K. Kleinsteuber et al.   BLOOD

Expression of IL-17, IL-23 and Their Receptors in Minor Salivary Glands of Patients with Primary Sjögren's Syndrome

(2012) Diana Mieliauskaite et al.   Clinical & Developmental Immunology

The biology and mechanism of action of suppressor of cytokine signaling 3

(2012) Jeffrey J. Babon et al.   GROWTH FACTORS

Suppression of Cytokine Signaling by SOCS3: Characterization of the Mode of Inhibition and the Basis of Its Specificity

(2012) Jeffrey J. Babon et al.   IMMUNITY

Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjögren's syndrome

(2011) Francesco Ciccia et al.   ANNALS OF THE RHEUMATIC DISEASES

Suppressors of Cytokine Signaling (SOCS) Proteins and JAK/STAT Pathways

(2011) Taiga Tamiya et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Leukemia Inhibitory Factor Inhibits T Helper 17 Cell Differentiation and Confers Treatment Effects of Neural Progenitor Cell Therapy in Autoimmune Disease

(2011) Wei Cao et al.   IMMUNITY

Pathogenic effect of interleukin-17A in induction of Sjögren's syndrome-like disease using adenovirus-mediated gene transfer

(2011) Cuong Q Nguyen et al.   ARTHRITIS RESEARCH & THERAPY

Disturbance of cytokine networks in Sjögren's syndrome

(2011) Pierre Youinou et al.   ARTHRITIS RESEARCH & THERAPY

Pathogenesis of Sjögrenʼs syndrome and therapeutic consequences

(2010) Xavier Mariette et al.   CURRENT OPINION IN RHEUMATOLOGY

IL-17 family member cytokines: Regulation and function in innate immunity

(2010) Joseph M. Reynolds et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The Candida Th17 response is dependent on mannan- and  -glucan-induced prostaglandin E2

(2010) S. P. Smeekens et al.   INTERNATIONAL IMMUNOLOGY

IL17: potential therapeutic target in Sjögren's syndrome using adenovirus-mediated gene transfer

(2010) Cuong Q Nguyen et al.   LABORATORY INVESTIGATION

Pathogenetic mechanisms in the initiation and perpetuation of Sjögren's syndrome

(2010) Michael Voulgarelis et al.   Nature Reviews Rheumatology

Systemic and Local Interleukin-17 and Linked Cytokines Associated with Sjögren’s Syndrome Immunopathogenesis

(2009) Gikas E. Katsifis et al.   AMERICAN JOURNAL OF PATHOLOGY

Sjögren’s syndrome: An old tale with a new twist

(2009) Byung Ha Lee et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis

(2009) Soraya Taleb et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TGF-  Promotes Th17 Cell Development through Inhibition of SOCS3

(2009) H. Qin et al.   JOURNAL OF IMMUNOLOGY

Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling

(2009) P. Pflegerl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function

(2009) Douglas C. Palmer et al.   TRENDS IN IMMUNOLOGY

Splenic suppressor of cytokine signaling 3 transgene expression affects T cell responses and prevents development of collagen-induced arthritis

(2008) Sharon Veenbergen et al.   ARTHRITIS AND RHEUMATISM

The many faces of the SOCS box

(2008) Julie Piessevaux et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Cytokine Signaling Modules in Inflammatory Responses

(2008) John J. O'Shea et al.   IMMUNITY

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE

Constitutive STAT3 activation in peripheral CD3+cells from patients with primary Sjögren's syndrome

(2008) H. L. Ramos et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY