Circulating levels of soluble MER in lupus reflect M2c activation of monocytes/macrophages, autoantibody specificities and disease activity

IL-17 Stimulates Differentiation of Human Anti-Inflammatory Macrophages and Phagocytosis of Apoptotic Neutrophils in Response to IL-10 and Glucocorticoids

(2013) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Vitamin K-dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity

(2013) Pedro Recarte-Pelz et al.   ARTHRITIS RESEARCH & THERAPY

Expansion of necrotic core and shedding of Mertk receptor in human carotid plaques: a role for oxidized polyunsaturated fatty acids?

(2012) Ulisse Garbin et al.   CARDIOVASCULAR RESEARCH

Genetic polymorphism of the growth arrest-specific 6 gene is associated with cutaneous vasculitis in Taiwanese patients with systemic lupus erythematosus

(2012) Chien-Sheng Wu et al.   CLINICAL RHEUMATOLOGY

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Shedding of the Mer Tyrosine Kinase Receptor Is Mediated by ADAM17 Protein through a Pathway Involving Reactive Oxygen Species, Protein Kinase Cδ, and p38 Mitogen-activated Protein Kinase (MAPK)

(2011) Edward Thorp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasma concentrations of Gas6 and sAxl correlate with disease activity in systemic lupus erythematosus

(2011) C. Ekman et al.   RHEUMATOLOGY

ADAM17: a molecular switch to control inflammation and tissue regeneration

(2011) Jürgen Scheller et al.   TRENDS IN IMMUNOLOGY

Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis

(2011) Jun Wu et al.   ARTHRITIS RESEARCH & THERAPY

Sustained remission of symptoms and improved health-related quality of life in patients with cryopyrin-associated periodic syndrome treated with canakinumab: results of a double-blind placebo-controlled randomized withdrawal study

(2011) Isabelle Koné-Paut et al.   ARTHRITIS RESEARCH & THERAPY

Plasma concentrations of Gas6 and soluble Axl correlate with disease and predict mortality in patients with critical limb ischemia

(2010) Carl Ekman et al.   CLINICAL BIOCHEMISTRY

Heme Oxygenase-1 expression in M-CSF-polarized M2 macrophages contributes to LPS-induced IL-10 release

(2010) Elena Sierra-Filardi et al.   IMMUNOBIOLOGY

Ectosomes Released by Polymorphonuclear Neutrophils Induce a MerTK-dependent Anti-inflammatory Pathway in Macrophages

(2010) Ceylan Eken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TNF-α, IL-6, and IL-1 expression is inhibited by GAS6 in monocytes/macrophages

(2010) Federica Alciato et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tumor necrosis factor α-converting enzyme (TACE/ADAM17) mediates ectodomain shedding of the scavenger receptor CD163

(2010) Anders Etzerodt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Gas6 is complexed to the soluble tyrosine kinase receptor Axl in human blood

(2010) C. EKMAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The role of defective clearance of apoptotic cells in systemic autoimmunity

(2010) Luis E. Muñoz et al.   Nature Reviews Rheumatology

Diagnostic utility of anti-Ro52 detection in systemic autoimmunity

(2010) M. Dugar et al.   POSTGRADUATE MEDICAL JOURNAL

TAM receptor ligands in lupus: Protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosus

(2010) Chang-Hee Suh et al.   ARTHRITIS RESEARCH & THERAPY

Hemoglobin and Heme Scavenger Receptors

(2009) Marianne Jensby Nielsen et al.   ANTIOXIDANTS & REDOX SIGNALING

Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features

(2009) T Vanden Berghe et al.   CELL DEATH AND DIFFERENTIATION

Novel TACE inhibitors in drug discovery: a review of patented compounds

(2009) Prashant R Murumkar et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Glucocorticoids Induce Protein S-Dependent Phagocytosis of Apoptotic Neutrophils by Human Macrophages

(2009) A. McColl et al.   JOURNAL OF IMMUNOLOGY

Survival and Migration of Human Dendritic Cells Are Regulated by an IFN- -Inducible Axl/Gas6 Pathway

(2009) S. Scutera et al.   JOURNAL OF IMMUNOLOGY

Mer tyrosine kinase (MerTK) promotes macrophage survival following exposure to oxidative stress

(2009) Adil Anwar et al.   JOURNAL OF LEUKOCYTE BIOLOGY

MerTK regulates thymic selection of autoreactive T cells

(2009) M. A. Wallet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased levels of circulating microparticles in primary Sjögren's syndrome, systemic lupus erythematosus and rheumatoid arthritis and relation with disease activity

(2009) Jérémie Sellam et al.   ARTHRITIS RESEARCH & THERAPY

B cell apotopes of the 60-kDa Ro/SSA and La/SSB autoantigens

(2008) Joanne H. Reed et al.   JOURNAL OF AUTOIMMUNITY

Hyperosmotic stress induces Axl activation and cleavage in cerebral endothelial cells

(2008) Imola Wilhelm et al.   JOURNAL OF NEUROCHEMISTRY