Evolution of a novel chimeric maltotriose transporter in Saccharomyces eubayanus from parent proteins unable to perform this function

In vivo recombination of Saccharomyces eubayanus maltose-transporter genes yields a chimeric transporter that enables maltotriose fermentation

(2019) Nick Brouwers et al.   PLoS Genetics

Diverse yeasts for diverse fermented beverages and foods

(2018) Chris Todd Hittinger et al.   CURRENT OPINION IN BIOTECHNOLOGY

Increased xylose affinity of Hxt2 through gene shuffling of hexose transporters in Saccharomyces cerevisiae

(2018) J.G. Nijland et al.   JOURNAL OF APPLIED MICROBIOLOGY

Structural, Physiological and Regulatory Analysis of Maltose Transporter Genes in Saccharomyces eubayanus CBS 12357T

(2018) Anja Brickwedde et al.   Frontiers in Microbiology

Inheritance of brewing-relevant phenotypes in constructed Saccharomyces cerevisiae × Saccharomyces eubayanus hybrids

(2017) Kristoffer Krogerus et al.   Microbial Cell Factories

Resistance to malaria through structural variation of red blood cell invasion receptors

(2017) Ellen M. Leffler et al.   SCIENCE

Alternative Saccharomyces interspecies hybrid combinations and their potential for low-temperature wort fermentation

(2017) Jarkko Nikulin et al.   YEAST

Evolutionary Engineering in Chemostat Cultures for Improved Maltotriose Fermentation Kinetics in Saccharomyces pastorianus Lager Brewing Yeast

(2017) Anja Brickwedde et al.   Frontiers in Microbiology

Ploidy influences the functional attributes of de novo lager yeast hybrids

(2016) Kristoffer Krogerus et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Novel brewing yeast hybrids: creation and application

(2016) Kristoffer Krogerus et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

STRUM: structure-based prediction of protein stability changes upon single-point mutation

(2016) Lijun Quan et al.   BIOINFORMATICS

Efficient engineering of marker-free synthetic allotetraploids of Saccharomyces

(2016) William G. Alexander et al.   FUNGAL GENETICS AND BIOLOGY

in silico Whole Genome Sequencer & Analyzer (iWGS): A Computational Pipeline to Guide the Design and Analysis of de novo Genome Sequencing Studies

(2016) X. Zhou et al.   G3-Genes Genomes Genetics

Complex Ancestries of Lager-Brewing Hybrids Were Shaped by Standing Variation in the Wild Yeast Saccharomyces eubayanus

(2016) David Peris et al.   PLoS Genetics

Structural Biology of the Major Facilitator Superfamily Transporters

(2015) Nieng Yan   Annual Review of Biophysics

A Large Set of Newly Created Interspecific Saccharomyces Hybrids Increases Aromatic Diversity in Lager Beers

(2015) Stijn Mertens et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

S. cerevisiae × S. eubayanus interspecific hybrid, the best of both worlds and beyond

(2015) Marit Hebly et al.   FEMS YEAST RESEARCH

The 100-genomes strains, anS. cerevisiaeresource that illuminates its natural phenotypic and genotypic variation and emergence as an opportunistic pathogen

(2015) Pooja K. Strope et al.   GENOME RESEARCH

New lager yeast strains generated by interspecific hybridization

(2015) Kristoffer Krogerus et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

The Genome Sequence ofSaccharomyces eubayanusand the Domestication of Lager-Brewing Yeasts

(2015) EmilyClare Baker et al.   MOLECULAR BIOLOGY AND EVOLUTION

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

Evidence for a Far East Asian origin of lager beer yeast

(2014) Jian Bing et al.   CURRENT BIOLOGY

A High-Definition View of Functional Genetic Variation from Natural Yeast Genomes

(2014) Anders Bergström et al.   MOLECULAR BIOLOGY AND EVOLUTION

Population structure and reticulate evolution ofSaccharomyces eubayanusand its lager-brewing hybrids

(2014) David Peris et al.   MOLECULAR ECOLOGY

Comprehensive variation discovery in single human genomes

(2014) Neil I Weisenfeld et al.   NATURE GENETICS

Engineering and Two-Stage Evolution of a Lignocellulosic Hydrolysate-Tolerant Saccharomyces cerevisiae Strain for Anaerobic Fermentation of Xylose from AFEX Pretreated Corn Stover

(2014) Lucas S. Parreiras et al.   PLoS One

Identification of loci that cause phenotypic variation in diverse species with the reciprocal hemizygosity test

(2014) David L. Stern   TRENDS IN GENETICS

Formation of Chimeric Genes by Copy-Number Variation as a Mutational Mechanism in Schizophrenia

(2013) Caitlin Rippey et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Regulations of sugar transporters: insights from yeast

(2013) J. Horák   CURRENT GENETICS

Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes

(2013) R. Malfavon-Borja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative physiology and fermentation performance of Saaz and Frohberg lager yeast strains and the parental speciesSaccharomyces eubayanus

(2013) Brian R. Gibson et al.   YEAST

Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data

(2012) M. Kearse et al.   BIOINFORMATICS

SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing

(2012) Anton Bankevich et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Characterization of the Saccharomyces bayanus-type AGT1 transporter of lager yeast

(2012) Virve Vidgren et al.   JOURNAL OF THE INSTITUTE OF BREWING

Characterization of maltotriose transporters from theSaccharomyces eubayanussubgenome of the hybridSaccharomyces pastorianuslager brewing yeast strain Weihenstephan 34/70

(2012) F.E.M. Cousseau et al.   LETTERS IN APPLIED MICROBIOLOGY

Genomic analysis of a key innovation in an experimental Escherichia coli population

(2012) Zachary D. Blount et al.   NATURE

Movement of DNA sequence recognition domains between non-orthologous proteins

(2012) Yoshikazu Furuta et al.   NUCLEIC ACIDS RESEARCH

Transposable Elements, Epigenetics, and Genome Evolution

(2012) N. V. Fedoroff   SCIENCE

Utilizing natural diversity to evolve protein function: applications towards thermostability

(2011) Megan F Cole et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Chimeric Genes as a Source of Rapid Evolution in Drosophila melanogaster

(2011) R. L. Rogers et al.   MOLECULAR BIOLOGY AND EVOLUTION

Microbe domestication and the identification of the wild genetic stock of lager-brewing yeast

(2011) D. Libkind et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

(2010) Olga Khersonsky and Dan S. Tawfik   Annual Review of Biochemistry

Repeated batch fermentation from raw starch using a maltose transporter and amylase expressing diploid yeast strain

(2010) Syun-ichi Yamakawa et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Rapid Expansion and Functional Divergence of Subtelomeric Gene Families in Yeasts

(2010) Chris A. Brown et al.   CURRENT BIOLOGY

The temperature dependence of maltose transport in ale and lager strains of brewer's yeast

(2010) Virve Vidgren et al.   FEMS YEAST RESEARCH

Dissection of genetically complex traits with extremely large pools of yeast segregants

(2010) Ian M. Ehrenreich et al.   NATURE

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Improved Fermentation Performance of a Lager Yeast after Repair of Its AGT1 Maltose and Maltotriose Transporter Genes

(2009) V. Vidgren et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genome Sequence of the Lager Brewing Yeast, an Interspecies Hybrid

(2009) Y. Nakao et al.   DNA RESEARCH

Modularity of MAP kinases allows deformation of their signalling pathways

(2009) Areez Mody et al.   NATURE CELL BIOLOGY

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Molecular Analysis of Maltotriose Active Transport and Fermentation by Saccharomyces cerevisiae Reveals a Determinant Role for the AGT1 Permease

(2008) S. L. Alves et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS

The Thr505and Ser557residues of the AGT1-encoded α-glucoside transporter are critical for maltotriose transport in Saccharomyces cerevisiae

(2008) A. Smit et al.   JOURNAL OF APPLIED MICROBIOLOGY

The Repertoire and Dynamics of Evolutionary Adaptations to Controlled Nutrient-Limited Environments in Yeast

(2008) David Gresham et al.   PLoS Genetics