Evolutionary Engineering in Chemostat Cultures for Improved Maltotriose Fermentation Kinetics in Saccharomyces pastorianus Lager Brewing Yeast

A new laboratory evolution approach to select for constitutive acetic acid tolerance in Saccharomyces cerevisiae and identification of causal mutations

(2016) Daniel González-Ramos et al.   Biotechnology for Biofuels

Next-generation sequencing analysis of lager brewing yeast strains reveals the evolutionary history of interspecies hybridization

(2016) Miki Okuno et al.   DNA RESEARCH

CRISPR/Cas9 advances engineering of microbial cell factories

(2016) Tadas Jakočiūnas et al.   METABOLIC ENGINEERING

Chromosomal Copy Number Variation in Saccharomyces pastorianus Is Evidence for Extensive Genome Dynamics in Industrial Lager Brewing Strains

(2015) M. van den Broek et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Evolutionary engineering to enhance starter culture performance in food fermentations

(2015) Herwig Bachmann et al.   CURRENT OPINION IN BIOTECHNOLOGY

S. cerevisiae × S. eubayanus interspecific hybrid, the best of both worlds and beyond

(2015) Marit Hebly et al.   FEMS YEAST RESEARCH

CRISPR/Cas9: a molecular Swiss army knife for simultaneous introduction of multiple genetic modifications in Saccharomyces cerevisiae

(2015) Robert Mans et al.   FEMS YEAST RESEARCH

Reducing alcohol levels in wines through rational and evolutionary engineering of Saccharomyces cerevisiae

(2015) Valentin Tilloy et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

The Genome Sequence ofSaccharomyces eubayanusand the Domestication of Lager-Brewing Yeasts

(2015) EmilyClare Baker et al.   MOLECULAR BIOLOGY AND EVOLUTION

Thermotolerant Yeast Strains Adapted by Laboratory Evolution Show Trade-Off at Ancestral Temperatures and Preadaptation to Other Stresses

(2015) Luis Caspeta et al.   mBio

Wort composition and its impact on the flavour-active higher alcohol and ester formation of beer - a review

(2014) Yang He et al.   JOURNAL OF THE INSTITUTE OF BREWING

Sequencing and Characterisation of Rearrangements in Three S. pastorianus Strains Reveals the Presence of Chimeric Genes and Gives Evidence of Breakpoint Reuse

(2014) Sarah K. Hewitt et al.   PLoS One

Altered sterol composition renders yeast thermotolerant

(2014) L. Caspeta et al.   SCIENCE

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

Variation inα-acetolactate production within the hybrid lager yeast groupSaccharomyces pastorianusand affirmation of the central role of theILV6gene

(2014) Brian Gibson et al.   YEAST

Saccharomyces pastorianus: genomic insights inspiring innovation for industry

(2014) Brian Gibson et al.   YEAST

Genome Sequence of Saccharomyces carlsbergensis , the World’s First Pure Culture Lager Yeast

(2014) Andrea Walther et al.   G3-Genes Genomes Genetics

Genome-scale analyses of butanol tolerance in Saccharomyces cerevisiae reveal an essential role of protein degradation

(2013) Daniel González-Ramos et al.   Biotechnology for Biofuels

Adaptive evolution of the lager brewing yeastSaccharomyces pastorianusfor improved growth under hyperosmotic conditions and its influence on fermentation performance

(2013) Jukka Ekberg et al.   FEMS YEAST RESEARCH

125thAnniversary Review: Developments in brewing and distilling yeast strains

(2013) Graham G. Stewart et al.   JOURNAL OF THE INSTITUTE OF BREWING

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

(2013) James E. DiCarlo et al.   NUCLEIC ACIDS RESEARCH

Genome duplication and mutations in ACE2 cause multicellular, fast-sedimenting phenotypes in evolved Saccharomyces cerevisiae

(2013) B. Oud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative physiology and fermentation performance of Saaz and Frohberg lager yeast strains and the parental speciesSaccharomyces eubayanus

(2013) Brian R. Gibson et al.   YEAST

De novo detection of copy number variation by co-assembly

(2012) Jurgen F. Nijkamp et al.   BIOINFORMATICS

Rapid identification ofSaccharomyces eubayanusand its hybrids

(2012) Reuben J. Pengelly et al.   FEMS YEAST RESEARCH

Characterization of the Saccharomyces bayanus-type AGT1 transporter of lager yeast

(2012) Virve Vidgren et al.   JOURNAL OF THE INSTITUTE OF BREWING

Characterization of maltotriose transporters from theSaccharomyces eubayanussubgenome of the hybridSaccharomyces pastorianuslager brewing yeast strain Weihenstephan 34/70

(2012) F.E.M. Cousseau et al.   LETTERS IN APPLIED MICROBIOLOGY

De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology

(2012) Jurgen F Nijkamp et al.   Microbial Cell Factories

Genome-wide analytical approaches for reverse metabolic engineering of industrially relevant phenotypes in yeast

(2011) Bart Oud et al.   FEMS YEAST RESEARCH

Engineering topology and kinetics of sucrose metabolism in Saccharomyces cerevisiae for improved ethanol yield

(2011) Thiago O. Basso et al.   METABOLIC ENGINEERING

Identification of Sc-type ILV6 as a target to reduce diacetyl formation in lager brewers' yeast

(2011) C.T. Duong et al.   METABOLIC ENGINEERING

Evolutionary engineered Saccharomyces cerevisiae wine yeast strains with increased in vivo flux through the pentose phosphate pathway

(2011) Axelle Cadière et al.   METABOLIC ENGINEERING

Deciphering the Hybridisation History Leading to the Lager Lineage Based on the Mosaic Genomes of Saccharomyces bayanus Strains NBRC1948 and CBS380T

(2011) Huu-Vang Nguyen et al.   PLoS One

Microbe domestication and the identification of the wild genetic stock of lager-brewing yeast

(2011) D. Libkind et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selection from Industrial Lager Yeast Strains of Variants with Improved Fermentation Performance in Very-High-Gravity Worts

(2010) A. Huuskonen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

Comparison of the MTT1- and MAL31-like maltose transporter genes in lager yeast strains

(2010) Judith Dietvorst et al.   FEMS MICROBIOLOGY LETTERS

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Genome Sequence of the Lager Brewing Yeast, an Interspecies Hybrid

(2009) Y. Nakao et al.   DNA RESEARCH

Molecular Analysis of Maltotriose Active Transport and Fermentation by Saccharomyces cerevisiae Reveals a Determinant Role for the AGT1 Permease

(2008) S. L. Alves et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Novel Evolutionary Engineering Approach for Accelerated Utilization of Glucose, Xylose, and Arabinose Mixtures by Engineered Saccharomyces cerevisiae Strains

(2008) H. W. Wisselink et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Reconstruction of the genome origins and evolution of the hybrid lager yeast Saccharomyces pastorianus

(2008) B. Dunn et al.   GENOME RESEARCH

Carbohydrate utilization and the lager yeast transcriptome during brewery fermentation

(2008) Brian R. Gibson et al.   YEAST