Mouse models of neurodegeneration: Know your question, know your mouse
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mouse models of neurodegeneration: Know your question, know your mouse
Authors
Keywords
-
Journal
Science Translational Medicine
Volume 11, Issue 493, Pages eaaq1818
Publisher
American Association for the Advancement of Science (AAAS)
Online
2019-05-23
DOI
10.1126/scitranslmed.aaq1818
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Transgenic and physiological mouse models give insights into different aspects of amyotrophic lateral sclerosis
- (2019) Francesca De Giorgio et al. Disease Models & Mechanisms
- Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis
- (2019) Leslie O. Goodwin et al. GENOME RESEARCH
- Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration
- (2019) Ze’ev Melamed et al. NATURE NEUROSCIENCE
- Emergence of synaptic and cognitive impairment in a mature-onset APP mouse model of Alzheimer’s disease
- (2019) Sarmi Sri et al. Acta Neuropathologica Communications
- Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP
- (2018) Frances K Wiseman et al. BRAIN
- Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis
- (2018) Pietro Fratta et al. EMBO JOURNAL
- TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD
- (2018) Matthew A. White et al. NATURE NEUROSCIENCE
- The maternal vaginal microbiome partially mediates the effects of prenatal stress on offspring gut and hypothalamus
- (2018) Eldin Jašarević et al. NATURE NEUROSCIENCE
- Voluntary running enhances glymphatic influx in awake behaving, young mice
- (2018) Stephanie von Holstein-Rathlou et al. NEUROSCIENCE LETTERS
- News Feature: What happens when lab animals go wild
- (2018) Carolyn Beans PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Early life experience drives structural variation of neural genomes in mice
- (2018) Tracy A. Bedrosian et al. SCIENCE
- Optimal housing temperatures for mice to mimic the thermal environment of humans: An experimental study
- (2018) Alexander W. Fischer et al. Molecular Metabolism
- Universal Alternative Splicing of Noncoding Exons
- (2018) Ira W. Deveson et al. Cell Systems
- Living inside the box: environmental effects on mouse models of human disease
- (2018) John P. Sundberg et al. Disease Models & Mechanisms
- Gene therapy rescues newborns with spinal muscular atrophy
- (2018) Cormac Sheridan NATURE BIOTECHNOLOGY
- Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell type
- (2018) Eszter Boldog et al. NATURE NEUROSCIENCE
- Somatic APP gene recombination in Alzheimer’s disease and normal neurons
- (2018) Ming-Hsiang Lee et al. NATURE
- Harnessing Genetic Complexity to Enhance Translatability of Alzheimer’s Disease Mouse Models: A Path toward Precision Medicine
- (2018) Sarah M. Neuner et al. NEURON
- Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder
- (2018) Martina Sgritta et al. NEURON
- Challenges and progress in interpretation of non-coding genetic variants associated with human disease
- (2017) Yizhou Zhu et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Genomes of the Mouse Collaborative Cross
- (2017) Anuj Srivastava et al. GENETICS
- Modeling human disease in rodents by CRISPR/Cas9 genome editing
- (2017) Marie-Christine Birling et al. MAMMALIAN GENOME
- Body Temperature Cycles Control Rhythmic Alternative Splicing in Mammals
- (2017) Marco Preußner et al. MOLECULAR CELL
- Lab mice's ancestral ‘Eve’ gets her genome sequenced
- (2017) Sara Reardon NATURE
- Reversing behavioural abnormalities in mice exposed to maternal inflammation
- (2017) Yeong Shin Yim et al. NATURE
- ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
- (2017) Yang Shi et al. NATURE
- Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring
- (2017) Sangdoo Kim et al. NATURE
- A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease
- (2017) Elvira Mass et al. NATURE
- Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium
- (2017) Terrence F Meehan et al. NATURE GENETICS
- Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy
- (2017) Emily V Fletcher et al. NATURE NEUROSCIENCE
- Comparative transcriptomics in human and mouse
- (2017) Alessandra Breschi et al. NATURE REVIEWS GENETICS
- Noncoding RNAs in neurodegeneration
- (2017) Evgenia Salta et al. NATURE REVIEWS NEUROSCIENCE
- A case-control study of hormonal exposures as etiologic factors for ALS in women
- (2017) James P.K. Rooney et al. NEUROLOGY
- Regulation of mRNA Translation in Neurons—A Matter of Life and Death
- (2017) Mridu Kapur et al. NEURON
- Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain
- (2017) Ira Espuny-Camacho et al. NEURON
- Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon inTAF1
- (2017) D. Cristopher Bragg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sloppy reporting on animal studies proves hard to change
- (2017) Martin Enserink SCIENCE
- Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2
- (2017) Catherine J. Peña et al. SCIENCE
- Severity of Demyelinating and Axonal Neuropathy Mouse Models Is Modified by Genes Affecting Structure and Function of Peripheral Nodes
- (2017) Kathryn H. Morelli et al. Cell Reports
- Cognitive Variability during Middle-Age: Possible Association with Neurodegeneration and Cognitive Reserve
- (2017) Daniel Ferreira et al. Frontiers in Aging Neuroscience
- Ongoing neurogenesis in the adult dentate gyrus mediates behavioral responses to ambiguous threat cues
- (2017) Lucas R. Glover et al. PLOS BIOLOGY
- Genetic Variation in the Social Environment Contributes to Health and Disease
- (2017) Amelie Baud et al. PLoS Genetics
- Genomes of the Mouse Collaborative Cross
- (2017) Anuj Srivastava et al. GENETICS
- Targeted Genetic Screen in Amyotrophic Lateral Sclerosis Reveals Novel Genetic Variants with Synergistic Effect on Clinical Phenotype
- (2017) Johnathan Cooper-Knock et al. Frontiers in Molecular Neuroscience
- Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
- (2016) Timothy R. Sampson et al. CELL
- Using the mouse to model human disease: increasing validity and reproducibility
- (2016) Monica J. Justice et al. Disease Models & Mechanisms
- Searching for cognitive enhancement in the Morris water maze: better and worse performance in D-amino acid oxidase knockout (Dao−/−) mice
- (2016) David Pritchett et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Men and mice: Relating their ages
- (2016) Sulagna Dutta et al. LIFE SCIENCES
- High-throughput discovery of novel developmental phenotypes
- (2016) Mary E. Dickinson et al. NATURE
- Evolution of Osteocrin as an activity-regulated factor in the primate brain
- (2016) Bulent Ataman et al. NATURE
- Normalizing the environment recapitulates adult human immune traits in laboratory mice
- (2016) Lalit K. Beura et al. NATURE
- Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing
- (2016) Jérôme Nicod et al. NATURE GENETICS
- Epigenetic germline inheritance of diet-induced obesity and insulin resistance
- (2016) Peter Huypens et al. NATURE GENETICS
- The effects of childhood maltreatment on brain structure, function and connectivity
- (2016) Martin H. Teicher et al. NATURE REVIEWS NEUROSCIENCE
- Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model
- (2016) Kathleen M. Schoch et al. NEURON
- Genetic Background Limits Generalizability of Genotype-Phenotype Relationships
- (2016) Laura J. Sittig et al. NEURON
- The Japanese diet from 1975 delays senescence and prolongs life span in SAMP8 mice
- (2016) Kazushi Yamamoto et al. NUTRITION
- Mechanisms linking circadian clocks, sleep, and neurodegeneration
- (2016) Erik S. Musiek et al. SCIENCE
- How neuroinflammation contributes to neurodegeneration
- (2016) R. M. Ransohoff SCIENCE
- ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function
- (2016) Aarti Sharma et al. Nature Communications
- The transgenerational inheritance of autism-like phenotypes in mice exposed to valproic acid during pregnancy
- (2016) Chang Soon Choi et al. Scientific Reports
- Erratum: Corrigendum: Survival Motor Neuron (SMN) protein is required for normal mouse liver development
- (2016) Eva Szunyogova et al. Scientific Reports
- Analysis of Individual Mouse Activity in Group Housed Animals of Different Inbred Strains using a Novel Automated Home Cage Analysis System
- (2016) Rasneer S. Bains et al. Frontiers in Behavioral Neuroscience
- Fine Mapping of a Dravet Syndrome Modifier Locus on Mouse Chromosome 5 and Candidate Gene Analysis by RNA-Seq
- (2016) Nicole A. Hawkins et al. PLoS Genetics
- Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes
- (2016) Thomas Arbogast et al. PLoS Genetics
- Mechanisms and Regulation of Alternative Pre-mRNA Splicing
- (2015) Yeon Lee et al. Annual Review of Biochemistry
- Cognitive Impairment, Neuroimaging, and Alzheimer Neuropathology in Mouse Models of Down Syndrome
- (2015) Eric D. Hamlett et al. Current Alzheimer Research
- How informative is the mouse for human gut microbiota research?
- (2015) T. L. A. Nguyen et al. Disease Models & Mechanisms
- Vapb/Amyotrophic lateral sclerosis 8 knock-in mice display slowly progressive motor behavior defects accompanying ER stress and autophagic response
- (2015) Frédérique Larroquette et al. HUMAN MOLECULAR GENETICS
- A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome
- (2015) Frances K. Wiseman et al. NATURE REVIEWS NEUROSCIENCE
- C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits
- (2015) J. Chew et al. SCIENCE
- Effect of Presymptomatic Body Mass Index and Consumption of Fat and Alcohol on Amyotrophic Lateral Sclerosis
- (2015) Mark H. B. Huisman et al. JAMA Neurology
- Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits
- (2015) Guilian Xu et al. Acta Neuropathologica Communications
- The Architecture of Parent-of-Origin Effects in Mice
- (2014) Richard Mott et al. CELL
- A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity
- (2014) Peter I. Joyce et al. HUMAN MOLECULAR GENETICS
- A comparative encyclopedia of DNA elements in the mouse genome
- (2014) Feng Yue et al. NATURE
- Preclinical research: Make mouse studies work
- (2014) Steve Perrin NATURE
- Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery
- (2014) E-Chiang Lee et al. NATURE BIOTECHNOLOGY
- Single App knock-in mouse models of Alzheimer's disease
- (2014) Takashi Saito et al. NATURE NEUROSCIENCE
- 'The clocks that time us'—circadian rhythms in neurodegenerative disorders
- (2014) Aleksandar Videnovic et al. Nature Reviews Neurology
- Comparison of the transcriptional landscapes between human and mouse tissues
- (2014) Shin Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution
- (2014) J. Vierstra et al. SCIENCE
- The mouse that roared: neural mechanisms of social hierarchy
- (2014) Fei Wang et al. TRENDS IN NEUROSCIENCES
- A Short Antisense Oligonucleotide Ameliorates Symptoms of Severe Mouse Models of Spinal Muscular Atrophy
- (2014) Jeffrey M Keil et al. Molecular Therapy-Nucleic Acids
- Is SOD1 loss of function involved in amyotrophic lateral sclerosis?
- (2013) Rachele A. Saccon et al. BRAIN
- Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway
- (2013) Christiane D. Wrann et al. Cell Metabolism
- Circadian clocks and neurodegenerative diseases: time to aggregate?
- (2013) Michael H Hastings et al. CURRENT OPINION IN NEUROBIOLOGY
- Bringing rigour to translational medicine
- (2013) David W. Howells et al. Nature Reviews Neurology
- The changing scene of amyotrophic lateral sclerosis
- (2013) Wim Robberecht et al. NATURE REVIEWS NEUROSCIENCE
- Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature
- (2013) K. M. Kokolus et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains
- (2013) Michelle M Simon et al. GENOME BIOLOGY
- The search for genetic mouse models of prodromal Parkinson's disease
- (2012) Gaynor A. Smith et al. EXPERIMENTAL NEUROLOGY
- Microglia and neurodegeneration: The role of systemic inflammation
- (2012) Colm Cunningham GLIA
- Mouse models of SMA: tools for disease characterization and therapeutic development
- (2012) Thomas W. Bebee et al. HUMAN GENETICS
- Strain Background Influences Neurotoxicity and Behavioral Abnormalities in Mice Expressing the Tetracycline Transactivator
- (2012) H. J. Han et al. JOURNAL OF NEUROSCIENCE
- Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis
- (2012) Christophe Verbeeck et al. Molecular Neurodegeneration
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- Adult neurogenesis: Optimizing hippocampal function to suit the environment
- (2011) Erica R. Glasper et al. BEHAVIOURAL BRAIN RESEARCH
- Transcript catalogs of human chromosome 21 and orthologous chimpanzee and mouse regions
- (2011) Xiaolu Sturgeon et al. MAMMALIAN GENOME
- Pathogenic exon-trapping by SVA retrotransposon and rescue in Fukuyama muscular dystrophy
- (2011) Mariko Taniguchi-Ikeda et al. NATURE
- Genomically humanized mice: technologies and promises
- (2011) Anny Devoy et al. NATURE REVIEWS GENETICS
- P525L FUS mutation is consistently associated with a severe form of juvenile Amyotrophic Lateral Sclerosis
- (2011) Amelia Conte et al. NEUROMUSCULAR DISORDERS
- Evaluation of Social and Physical Enrichment in Modulation of Behavioural Phenotype in C57BL/6J Female Mice
- (2011) Natalia Kulesskaya et al. PLoS One
- Aggregation modulating elements in mutant human superoxide dismutase 1
- (2010) Celeste M. Karch et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The role of habituation in hippocampus-dependent spatial working memory tasks: Evidence from GluA1 AMPA receptor subunit knockout mice
- (2010) David J. Sanderson et al. HIPPOCAMPUS
- A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions
- (2010) Tao Yu et al. HUMAN MOLECULAR GENETICS
- Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
- (2010) Carol Kilkenny et al. PLOS BIOLOGY
- New approaches for modelling sporadic genetic disease in the mouse
- (2009) E. M. C. Fisher et al. Disease Models & Mechanisms
- Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss
- (2009) Ángeles Mencía et al. NATURE GENETICS
- An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice
- (2009) Morag A Lewis et al. NATURE GENETICS
- Dynamic DNA methylation programs persistent adverse effects of early-life stress
- (2009) Chris Murgatroyd et al. NATURE NEUROSCIENCE
- Brain development under stress: Hypotheses of glucocorticoid actions revisited
- (2009) Melly S. Oitzl et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Design, power, and interpretation of studies in the standard murine model of ALS
- (2008) Sean Scott et al. Amyotrophic Lateral Sclerosis
- Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death
- (2008) H. S. Ilieva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The links between membrane composition, metabolic rate and lifespan
- (2006) A.J. Hulbert COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search