A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease

Langerhans cell histiocytosis: therapeutic strategy and outcome in a 30-year nationwide cohort of 1478 patients under 18 years of age

(2016) Charlotte Rigaud et al.   BRITISH JOURNAL OF HAEMATOLOGY

BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy

(2016) Sébastien Héritier et al.   JOURNAL OF CLINICAL ONCOLOGY

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Specification of tissue-resident macrophages during organogenesis

(2016) E. Mass et al.   SCIENCE

How neuroinflammation contributes to neurodegeneration

(2016) R. M. Ransohoff   SCIENCE

The role of IL-17 in CNS diseases

(2015) Ari Waisman et al.   ACTA NEUROPATHOLOGICA

TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model

(2015) Yaming Wang et al.   CELL

High burden and pervasive positive selection of somatic mutations in normal human skin

(2015) I. Martincorena et al.   SCIENCE

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

(2015) E. L. Diamond et al.   Cancer Discovery

Consensus guidelines for the diagnosis and clinical management of Erdheim-Chester disease

(2014) E. L. Diamond et al.   BLOOD

BRAF-V600Eexpression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups

(2014) Marie-Luise Berres et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

Genome sequencing of normal cells reveals developmental lineages and mutational processes

(2014) Sam Behjati et al.   NATURE

Sailfish enables alignment-free isoform quantification from RNA-seq reads using lightweight algorithms

(2014) Rob Patro et al.   NATURE BIOTECHNOLOGY

Hematopoietic Stem Cell Origin of BRAFV600E Mutations in Hairy Cell Leukemia

(2014) S. S. Chung et al.   Science Translational Medicine

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

The brain’s best friend: microglial neurotoxicity revisited

(2013) Sabine Hellwig et al.   Frontiers in Cellular Neuroscience

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses

(2012) J. Haroche et al.   BLOOD

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

B-RAF Mutant Alleles Associated with Langerhans Cell Histiocytosis, a Granulomatous Pediatric Disease

(2012) Takeshi Satoh et al.   PLoS One

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids

(2011) Rosa Rademakers et al.   NATURE GENETICS

Recurrent BRAF mutations in Langerhans cell histiocytosis

(2010) G. Badalian-Very et al.   BLOOD

Incidence and pattern of radiological central nervous system Langerhans cell histiocytosis in children: A population based study

(2010) Evaldas Laurencikas et al.   PEDIATRIC BLOOD & CANCER

A Novel Mouse Model of Inflammatory Bowel Disease Links Mammalian Target of Rapamycin-Dependent Hyperproliferation of Colonic Epithelium to Inflammation-Associated Tumorigenesis

(2009) Lin Deng et al.   AMERICAN JOURNAL OF PATHOLOGY

Pattern and Course of Neurodegeneration in Langerhans Cell Histiocytosis

(2008) Martha Wnorowski et al.   JOURNAL OF PEDIATRICS

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

(2008) J. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA