Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy

Sensory-Derived Glutamate Regulates Presynaptic Inhibitory Terminals in Mouse Spinal Cord

(2016) Michael Mende et al.   NEURON

SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNΔ7 mouse model of SMA

(2015) Vicki L. McGovern et al.   HUMAN MOLECULAR GENETICS

Disease Mechanisms and Therapeutic Approaches in Spinal Muscular Atrophy

(2015) S. Tisdale et al.   JOURNAL OF NEUROSCIENCE

Distinct Cell- and Layer-Specific Expression Patterns and Independent Regulation of Kv2 Channel Subtypes in Cortical Pyramidal Neurons

(2015) H. I. Bishop et al.   JOURNAL OF NEUROSCIENCE

Activity Regulates the Incidence of Heteronymous Sensory-Motor Connections

(2015) Alana I. Mendelsohn et al.   NEURON

Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability

(2015) Anna-Claire Devlin et al.   Nature Communications

Sarcomere length organization as a design for cooperative function amongst all lumbar spine muscles

(2014) Derek P. Zwambag et al.   JOURNAL OF BIOMECHANICS

Characterization of motor units in behaving adult mice shows a wide primary range

(2014) Laura K. Ritter et al.   JOURNAL OF NEUROPHYSIOLOGY

Kv2 Channel Regulation of Action Potential Repolarization and Firing Patterns in Superior Cervical Ganglion Neurons and Hippocampal CA1 Pyramidal Neurons

(2014) P. W. Liu et al.   JOURNAL OF NEUROSCIENCE

Normal Distribution of VGLUT1 Synapses on Spinal Motoneuron Dendrites and Their Reorganization after Nerve Injury

(2014) T. M. Rotterman et al.   JOURNAL OF NEUROSCIENCE

Decursin attenuates kainic acid-induced seizures in mice

(2014) Jong-Keun Lee et al.   NEUROREPORT

Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons

(2014) Brian J. Wainger et al.   Cell Reports

Redistribution of Kv2.1 ion channels on spinal motoneurons following peripheral nerve injury

(2013) Shannon H. Romer et al.   BRAIN RESEARCH

Musculotopic organization of the motor neurons supplying the mouse hindlimb muscles: a quantitative study using Fluoro-Gold retrograde tracing

(2013) Tímea Bácskai et al.   Brain Structure & Function

An SMN-Dependent U12 Splicing Event Essential for Motor Circuit Function

(2012) Francesco Lotti et al.   CELL

Motor Neuron Rescue in Spinal Muscular Atrophy Mice Demonstrates That Sensory-Motor Defects Are a Consequence, Not a Cause, of Motor Neuron Dysfunction

(2012) R. G. Gogliotti et al.   JOURNAL OF NEUROSCIENCE

Survival Motor Neuron Protein in Motor Neurons Determines Synaptic Integrity in Spinal Muscular Atrophy

(2012) T. L. Martinez et al.   JOURNAL OF NEUROSCIENCE

Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy

(2011) K. K. Y. Ling et al.   HUMAN MOLECULAR GENETICS

Postsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy

(2011) Cathleen M. Lutz et al.   JOURNAL OF CLINICAL INVESTIGATION

Early Functional Impairment of Sensory-Motor Connectivity in a Mouse Model of Spinal Muscular Atrophy

(2011) George Z. Mentis et al.   NEURON

Distribution Pattern of Muscle Fiber Types in the Perivertebral Musculature of Two Different Sized Species of Mice

(2010) Bettina Hesse et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Identifying roles for neurotransmission in circuit assembly: Insights gained from multiple model systems and experimental approaches

(2010) Adam Bleckert et al.   BIOESSAYS

From circuits to behaviour: motor networks in vertebrates

(2010) Lidia Garcia-Campmany et al.   CURRENT OPINION IN NEUROBIOLOGY

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Stringent Specificity in the Construction of a GABAergic Presynaptic Inhibitory Circuit

(2009) J. Nicholas Betley et al.   CELL

Clinical Outcome Measures in Spinal Muscular Atrophy

(2009) Jacqueline Montes et al.   JOURNAL OF CHILD NEUROLOGY

Functionally Reduced Sensorimotor Connections Form with Normal Specificity Despite Abnormal Muscle Spindle Development: The Role of Spindle-Derived Neurotrophin 3

(2009) N. A. Shneider et al.   JOURNAL OF NEUROSCIENCE

Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect

(2008) T. O. Gavrilina et al.   HUMAN MOLECULAR GENETICS

V3 Spinal Neurons Establish a Robust and Balanced Locomotor Rhythm during Walking

(2008) Ying Zhang et al.   NEURON