A double‐blind, randomized, placebo‐controlled study to assess the efficacy of Andrographis paniculata standardized extract (ParActin®) on pain reduction in subjects with knee osteoarthritis

Effect of glucosamine and chondroitin sulfate in symptomatic knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials

(2018) Mario Simental-Mendía et al.   RHEUMATOLOGY INTERNATIONAL

Andrographolide protects chondrocytes from oxidative stress injury by activation of the Keap1-Nrf2-Are signaling pathway

(2018) Bo Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Knee osteoarthritis: pathophysiology and current treatment modalities

(2018) Juan C Mora et al.   Journal of Pain Research

Andrographolide Benefits Rheumatoid Arthritis via Inhibiting MAPK Pathways

(2017) Zun-zhong Li et al.   INFLAMMATION

Negative Regulators of JAK/STAT Signaling in Rheumatoid Arthritis and Osteoarthritis

(2017) Charles Malemud   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ethnopharmacological Approaches for Therapy of Jaundice: Part II. Highly Used Plant Species from Acanthaceae, Euphorbiaceae, Asteraceae, Combretaceae, and Fabaceae Families

(2017) Devesh Tewari et al.   Frontiers in Pharmacology

Inhibitory effects of andrographolide on activated macrophages and adjuvant-induced arthritis

(2017) Swati Gupta et al.   INFLAMMOPHARMACOLOGY

Andrographis paniculata decreases fatigue in patients with relapsing-remitting multiple sclerosis: a 12-month double-blind placebo-controlled pilot study

(2016) J. C. Bertoglio et al.   BMC Neurology

Are nutraceuticals the modern panacea? From myth to science

(2016) Pietro Minuz et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Current advances in therapies for osteoarthritis

(2016) Kenneth C. Kalunian   CURRENT OPINION IN RHEUMATOLOGY

Non-surgical treatments for the management of early osteoarthritis

(2016) Giuseppe Filardo et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis

(2016) William H. Robinson et al.   Nature Reviews Rheumatology

Comparative Effectiveness of Pharmacologic Interventions for Knee Osteoarthritis

(2015) Raveendhara R. Bannuru et al.   ANNALS OF INTERNAL MEDICINE

Andrographolide inhibits the migration, invasion and matrix metalloproteinase expression of rheumatoid arthritis fibroblast-like synoviocytes via inhibition of HIF-1α signaling

(2015) Guo-feng Li et al.   LIFE SCIENCES

Inhibition of matrix metalloproteinases and inducible nitric oxide synthase by andrographolide in human osteoarthritic chondrocytes

(2014) Qian-hai Ding et al.   Modern Rheumatology

Review on Liver Inflammation and Antiinflammatory Activity ofAndrographis paniculatafor Hepatoprotection

(2014) Lee Suan Chua   PHYTOTHERAPY RESEARCH

Andrographis paniculata Leaf Extract Prevents Thioacetamide-Induced Liver Cirrhosis in Rats

(2014) Daleya Abdulaziz Bardi et al.   PLoS One

Andrographis paniculata(Burm. f.) Wall. ex Nees: A Review of Ethnobotany, Phytochemistry, and Pharmacology

(2014) Md. Sanower Hossain et al.   TheScientificWorldJOURNAL

Fatigue in Healthy and Diseased Individuals

(2013) Josef Finsterer et al.   American Journal of Hospice & Palliative Medicine

Andrographolide protects against cigarette smoke-induced oxidative lung injury via augmentation of Nrf2 activity

(2012) SP Guan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Serum Creatinine Determined by Jaffe, Enzymatic Method, and Isotope Dilution-Liquid Chromatography-Mass Spectrometry in Patients Under Hemodialysis

(2012) Wen-Sheng Liu et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Management of osteoarthritis of the knee

(2012) K. L. Bennell et al.   BMJ-British Medical Journal

Andrographolide induces cell cycle arrest and apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes

(2011) Jie Yan et al.   CELL BIOLOGY AND TOXICOLOGY

Immunomodulatory activity of andrographolide on macrophage activation and specific antibody response

(2010) Wei Wang et al.   ACTA PHARMACOLOGICA SINICA

Study of anti-inflammatory activities of the pure compounds from Andrographis paniculata (burm.f.) Nees and their effects on gene expression

(2010) Warisara Parichatikanond et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mechanical signals control SOX-9, VEGF, and c-Myc expression and cell proliferation during inflammation via integrin-linked kinase, B-Raf, and ERK1/2-dependent signaling in articular chondrocytes

(2010) Priyangi M Perera et al.   ARTHRITIS RESEARCH & THERAPY

Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial

(2009) R. A. Burgos et al.   CLINICAL RHEUMATOLOGY

MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation – divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation

(2009) B.-C. Sondergaard et al.   OSTEOARTHRITIS AND CARTILAGE

A Review of Evidence-Based Medicine for Glucosamine and Chondroitin Sulfate Use in Knee Osteoarthritis

(2008) C. Thomas Vangsness et al.   ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY

Andrographolide reduces IL-2 production in T-cells by interfering with NFAT and MAPK activation

(2008) María D. Carretta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY