Inhibition of matrix metalloproteinases and inducible nitric oxide synthase by andrographolide in human osteoarthritic chondrocytes

Andrographolide inhibits human umbilical vein endothelial cell invasion and migration by regulating MMP-2 and MMP-9 during angiogenesis

(2012) P. Pratheeshkumar et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

Aging and osteoarthritis

(2011) Richard F. Loeser   CURRENT OPINION IN RHEUMATOLOGY

Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264.7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway

(2011) Ko-Chen Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Desperately looking for the right target in osteoarthritis: the anti-IL-1 strategy

(2011) Xavier Chevalier et al.   ARTHRITIS RESEARCH & THERAPY

NF-κB Signaling: Multiple Angles to Target OA

(2010) Kenneth B. Marcu et al.   CURRENT DRUG TARGETS

Anticytokine Therapy for Osteoarthritis

(2010) Charles J. Malemud   DRUGS & AGING

Inhibitory effects of andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signaling pathway

(2010) Yi-Chieh Lee et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Andrographolide could inhibit human colorectal carcinoma Lovo cells migration and invasion via down-regulation of MMP-7 expression

(2009) Ming-Der Shi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial

(2009) R. A. Burgos et al.   CLINICAL RHEUMATOLOGY

Joint Diseases and Matrix Metalloproteinases: A Role for MMP-13

(2008) Hironari Takaishi et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Synthesis and evaluation of antibacterial activities of andrographolide analogues

(2008) Xiaojian Jiang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Nitric oxide in inflammation and pain associated with osteoarthritis

(2008) Steven B Abramson   ARTHRITIS RESEARCH & THERAPY