Biomarkers of Oxidative Stress in Metabolic Syndrome and Associated Diseases

Impaired Vascular Redox Signaling in the Vascular Complications of Obesity and Diabetes Mellitus

(2018) Ioannis Akoumianakis et al.   ANTIOXIDANTS & REDOX SIGNALING

The role of the thioredoxin/thioredoxin reductase system in the metabolic syndrome: towards a possible prognostic marker?

(2018) Alexey A. Tinkov et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Small-molecule luminescent probes for the detection of cellular oxidizing and nitrating species

(2018) Jacek Zielonka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Altered Gut Microbiota: A Link Between Diet and the Metabolic Syndrome

(2018) Manuel T. Velasquez   Metabolic Syndrome and Related Disorders

Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine

(2018) Rafael Radi   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic potential of DNA-aptamers raised against AGE-RAGE axis in diabetes-related complications

(2018) Sho-ichi Yamagish et al.   CURRENT PHARMACEUTICAL DESIGN

Impact of Nutritional and Environmental Factors on Inflammation, Oxidative Stress, and the Microbiome

(2018) Gang Liu et al.   Biomed Research International

Gut microbiota and health: connecting actors across the metabolic system

(2018) F. Fava et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

(2017) Glenn R. Gibson et al.   Nature Reviews Gastroenterology & Hepatology

Measurement and Clinical Significance of Biomarkers of Oxidative Stress in Humans

(2017) Ilaria Marrocco et al.   Oxidative Medicine and Cellular Longevity

Gut microbiome in chronic kidney disease: challenges and opportunities

(2017) Anitha Nallu et al.   Translational Research

A red yeast rice-olive extract supplement reduces biomarkers of oxidative stress, OxLDL and Lp-PLA2, in subjects with metabolic syndrome: a randomised, double-blind, placebo-controlled trial

(2017) Nina Hermans et al.   Trials

Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study

(2017) Marta Guasch‐Ferré et al.   Journal of the American Heart Association

The Potential Role of Antioxidants in Metabolic Syndrome

(2016) Bianca Martins Gregório et al.   CURRENT PHARMACEUTICAL DESIGN

Foods contributing to vitamin B6, folate, and vitamin B12 intakes and biomarkers status in European adolescents: The HELENA study

(2016) Iris Iglesia et al.   EUROPEAN JOURNAL OF NUTRITION

Hyperglycemia-associated alterations in cellular signaling and dysregulated mitochondrial bioenergetics in human metabolic disorders

(2016) George B. Stefano et al.   EUROPEAN JOURNAL OF NUTRITION

Mitochondrial biogenesis and clearance: a balancing act

(2016) Christina Ploumi et al.   FEBS Journal

Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies

(2016) Vibha Rani et al.   LIFE SCIENCES

NADPH: new oxygen for the ROS theory of aging

(2016) Pablo J. Fernandez-Marcos et al.   Oncotarget

The Role of AGE/RAGE Signaling in Diabetes-Mediated Vascular Calcification

(2016) Amber M. Kay et al.   Journal of Diabetes Research

The economic impact of obesity in the United States

(2016) Ross Hammond et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Uncoupling of Endothelial Nitric Oxide Synthase in Perivascular Adipose Tissue of Diet-Induced Obese MiceSignificance

(2015) Ning Xia et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Investigation of the Oxidative Stress-Related Parameters in Type 2 Diabetes Mellitus

(2015) Ouassila Aouacheri et al.   Canadian Journal of Diabetes

Crosstalk between advanced glycation end products (AGEs)-receptor RAGE axis and dipeptidyl peptidase-4-incretin system in diabetic vascular complications

(2015) Sho-ichi Yamagishi et al.   Cardiovascular Diabetology

Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis

(2015) Yunes Panahi et al.   CLINICAL NUTRITION

Diabetic Cardiovascular Disease Induced by Oxidative Stress

(2015) Yosuke Kayama et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome

(2015) Olesya Ilkun et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The interplay of extracellular matrix and microbiome in urothelial bladder cancer

(2015) Massimo Alfano et al.   Nature Reviews Urology

Rescue of Fructose-Induced Metabolic Syndrome by Antibiotics or Faecal Transplantation in a Rat Model of Obesity

(2015) Blanda Di Luccia et al.   PLoS One

Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease—FLAVURS: a randomized controlled trial

(2014) Anna L Macready et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Beneficial Effects of Rosuvastatin Treatment in Patients With Metabolic Syndrome

(2014) Cem Bostan et al.   ANGIOLOGY

Cardiac NO signalling in the metabolic syndrome

(2014) O Pechánová et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mitochondrial alteration in type 2 diabetes and obesity: An epigenetic link

(2014) Zhiyong Cheng et al.   CELL CYCLE

Role of Vascular Oxidative Stress in Obesity and Metabolic Syndrome

(2014) J.-Y. Youn et al.   DIABETES

Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes

(2014) Nathalie Esser et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Differences in the redox status of human visceral and subcutaneous adipose tissues – relationships to obesity and metabolic risk

(2014) Aleksandra Jankovic et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Enhanced ROS production and oxidative damage in subcutaneous white adipose tissue mitochondria in obese and type 2 diabetes subjects

(2014) Mrittika Chattopadhyay et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Global trends in the prevalence of overweight and obesity

(2014) Camilla Schmidt Morgen et al.   Nature Reviews Endocrinology

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

(2014) Colin Hill et al.   Nature Reviews Gastroenterology & Hepatology

Association of fructose consumption and components of metabolic syndrome in human studies: A systematic review and meta-analysis

(2014) Roya Kelishadi et al.   NUTRITION

Association of altered hemorheology with oxidative stress and inflammation in metabolic syndrome

(2014) Prajwal Gyawali et al.   REDOX REPORT

The role of mitochondria in the aetiology of insulin resistance and type 2 diabetes

(2013) Sheree D. Martin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Vascular Complications of Diabetes: Mechanisms of Injury and Protective Factors

(2013) Christian Rask-Madsen et al.   Cell Metabolism

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

(2013) Marc Liesa et al.   Cell Metabolism

Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

(2013) Brian W. Parks et al.   Cell Metabolism

Production of Reactive Oxygen Species in the Diabetic Heart

(2013) Yasushi Teshima et al.   CIRCULATION JOURNAL

Do Antioxidant Vitamins Ameliorate the Beneficial Effects of Exercise Training on Insulin Sensitivity?

(2013) Carl J. Lavie et al.   Journal of Cardiopulmonary Rehabilitation and Prevention

Potential Efficacy of Broccoli Sprouts as a Unique Supplement for Management of Type 2 Diabetes and Its Complications

(2013) Zahra Bahadoran et al.   JOURNAL OF MEDICINAL FOOD

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Mediterranean diet and non enzymatic antioxidant capacity in the PREDIMED study: Evidence for a mechanism of antioxidant tuning

(2013) R. Zamora-Ros et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Increased oxidative stress in obesity: Implications for metabolic syndrome, diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer

(2013) Morihiro Matsuda et al.   Obesity Research & Clinical Practice

Isoprostanes and 4-Hydroxy-2-nonenal: Markers or Mediators of Disease? Focus on Rett Syndrome as a Model of Autism Spectrum Disorder

(2013) Cinzia Signorini et al.   Oxidative Medicine and Cellular Longevity

Oxidative stress in vascular disease and its pharmacological prevention

(2013) Huige Li et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals

(2012) Anna-Maria Joseph et al.   AGING CELL

Myeloperoxidase: A Leukocyte-Derived Protagonist of Inflammation and Cardiovascular Disease

(2012) Claudia Nussbaum et al.   ANTIOXIDANTS & REDOX SIGNALING

Evidence-based antioxidant activity of the essential oil from Fructus A. zerumbet on cultured human umbilical vein endothelial cells’ injury induced by ox-LDL

(2012) Xiang-chun Shen et al.   BMC Complementary and Alternative Medicine

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

The Polyphenols Resveratrol and S17834 Prevent the Structural and Functional Sequelae of Diet-Induced Metabolic Heart Disease in Mice

(2012) Fuzhong Qin et al.   CIRCULATION

Coenzyme Q10 attenuates diastolic dysfunction, cardiomyocyte hypertrophy and cardiac fibrosis in the db/db mouse model of type 2 diabetes

(2012) K. Huynh et al.   DIABETOLOGIA

Impact of the quantity and flavonoid content of fruits and vegetables on markers of intake in adults with an increased risk of cardiovascular disease: the FLAVURS trial

(2012) Mary F. Chong et al.   EUROPEAN JOURNAL OF NUTRITION

Actions of “antioxidants” in the protection against atherosclerosis

(2012) Maria E. Lönn et al.   FREE RADICAL BIOLOGY AND MEDICINE

The type and quantity of dietary fat and carbohydrate alter faecal microbiome and short-chain fatty acid excretion in a metabolic syndrome ‘at-risk’ population

(2012) F Fava et al.   INTERNATIONAL JOURNAL OF OBESITY

Increased Cellular and Circulating Biomarkers of Oxidative Stress in Nascent Metabolic Syndrome

(2012) Ishwarlal Jialal et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Quercetin Ameliorates Cardiovascular, Hepatic, and Metabolic Changes in Diet-Induced Metabolic Syndrome in Rats

(2012) Sunil K. Panchal et al.   JOURNAL OF NUTRITION

Impaired enzymatic antioxidant defense in erythrocytes of women with general and abdominal obesity

(2012) Farshad Amirkhizi et al.   Obesity Research & Clinical Practice

Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats

(2012) Pankaj K. Bagul et al.   PHARMACOLOGICAL RESEARCH

A Randomized, Double-Blind, Placebo-Controlled Crossover Study of Coenzyme Q10 Therapy in Hypertensive Patients With the Metabolic Syndrome

(2011) J. M. Young et al.   AMERICAN JOURNAL OF HYPERTENSION

Chronic Inflammatory Disorders and Their Redox Control: From Molecular Mechanisms to Therapeutic Opportunities

(2011) Valerio Chiurchiù et al.   ANTIOXIDANTS & REDOX SIGNALING

Resolution of Mitochondrial Oxidative Stress Rescues Coronary Collateral Growth in Zucker Obese Fatty Rats

(2011) Yuh Fen Pung et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

(2011) Silvie Timmers et al.   Cell Metabolism

High density lipoprotein cholesterol level is a robust predictor of lipid peroxidation irrespective of gender, age, obesity, and inflammatory or metabolic biomarkers

(2011) Sieglinde Zelzer et al.   CLINICA CHIMICA ACTA

Resveratrol modifies risk factors for coronary artery disease in swine with metabolic syndrome and myocardial ischemia

(2011) Michael P. Robich et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine as a biomarker in type 2 diabetes

(2011) Kasper Broedbaek et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cross talk between mitochondria and NADPH oxidases

(2011) Sergey Dikalov   FREE RADICAL BIOLOGY AND MEDICINE

The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/–/ApoE–/– mice

(2011) John R. Mercer et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of Vitamin E on Plasma Lipid Status and Oxidative Stress in Chinese Women with Metabolic Syndrome

(2011) Qiuzhen Wang et al.   INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH

Global Profiling of Reactive Oxygen and Nitrogen Species in Biological Systems

(2011) Jacek Zielonka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity Induces Signs of Premature Cardiac Aging in Younger Patients

(2011) Bernd Niemann et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

(2011) A. S. Rambold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Starches, Sugars and Obesity

(2011) Erik E. J. G. Aller et al.   Nutrients

Fructose: a highly lipogenic nutrient implicated in insulin resistance, hepatic steatosis, and the metabolic syndrome

(2010) Mark J. Dekker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Oxidative Stress as Pathogenesis of Cardiovascular Risk Associated with Metabolic Syndrome

(2010) Hajime Otani   ANTIOXIDANTS & REDOX SIGNALING

Impaired Redox Signaling and Antioxidant Gene Expression in Endothelial Cells in Diabetes: A Role for Mitochondria and the Nuclear Factor-E2-Related Factor 2-Kelch-Like ECH-Associated Protein 1 Defense Pathway

(2010) Xinghua Cheng et al.   ANTIOXIDANTS & REDOX SIGNALING

Involvement of RAGE, NADPH Oxidase, and Ras/Raf-1 Pathway in Glycated LDL-Induced Expression of Heat Shock Factor-1 and Plasminogen Activator Inhibitor-1 in Vascular Endothelial Cells

(2010) Ganesh V. Sangle et al.   ENDOCRINOLOGY

Is oxidative stress a therapeutic target in cardiovascular disease?

(2010) Thomas Münzel et al.   EUROPEAN HEART JOURNAL

Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: Another inconvenient truth

(2010) Jacek Zielonka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Obesity and the metabolic syndrome: role of different dietary macronutrient distribution patterns and specific nutritional components on weight loss and maintenance

(2010) Itziar Abete et al.   NUTRITION REVIEWS

Metabolic Effects of Fructose and the Worldwide Increase in Obesity

(2010) Luc Tappy et al.   PHYSIOLOGICAL REVIEWS

Gut Microbiota in Health and Disease

(2010) Inna Sekirov et al.   PHYSIOLOGICAL REVIEWS

Insulin signaling meets mitochondria in metabolism

(2010) Zhiyong Cheng et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Effects of extensively oxidized low-density lipoprotein on mitochondrial function and reactive oxygen species in porcine aortic endothelial cells

(2009) Subir K. Roy Chowdhury et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reactive oxygen species and the control of vascular function

(2009) Michael S. Wolin   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

NADPH Oxidases: Functions and Pathologies in the Vasculature

(2009) Bernard Lassègue et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sarcopenia of aging: Underlying cellular mechanisms and protection by calorie restriction

(2009) Emanuele Marzetti et al.   BIOFACTORS

Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study

(2009) Sarah Egert et al.   BRITISH JOURNAL OF NUTRITION

Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction

(2009) Csaba Szabo   BRITISH JOURNAL OF PHARMACOLOGY

Coenzyme Q10 improves diastolic function in children with idiopathic dilated cardiomyopathy

(2009) Armen Kocharian et al.   CARDIOLOGY IN THE YOUNG

High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity

(2009) Marie A. Hildebrandt et al.   GASTROENTEROLOGY

Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response

(2009) S E Perez-Pozo et al.   INTERNATIONAL JOURNAL OF OBESITY

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

(2009) Kimber L. Stanhope et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Oxidative stress and metabolic syndrome

(2009) Christian K. Roberts et al.   LIFE SCIENCES

Endothelium-Driven Myocardial Growth or Nitric Oxide at the Crossroads

(2009) Daniela Tirziu et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Endothelial dysfunction and vascular inflammation in Type 2 diabetes: interaction of AGE/RAGE and TNF-α signaling

(2008) Anna Csiszar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Chemokines in Vascular Dysfunction and Remodeling

(2008) Andreas Schober   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Oxidative stress markers, C-reactive protein and heat shock protein 70 levels in subjects with metabolic syndrome

(2008) Ferah Armutcu et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Redox-based regulation of signal transduction: Principles, pitfalls, and promises

(2008) Yvonne M.W. Janssen-Heininger et al.   FREE RADICAL BIOLOGY AND MEDICINE

Increased oxidative stress precedes the onset of high-fat diet–induced insulin resistance and obesity

(2008) Naoto Matsuzawa-Nagata et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Symbiotic gut microbes modulate human metabolic phenotypes

(2008) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction

(2007) Abdulrahman K. Doughan et al.   CIRCULATION RESEARCH