Mitochondrial alteration in type 2 diabetes and obesity: An epigenetic link

Targeting mitochondrial alterations to prevent type 2 diabetes-Evidence from studies of dietary redox-active compounds

(2014) Zhiyong Cheng et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Mitochondria and Metabolic Homeostasis

(2013) Zhiyong Cheng et al.   ANTIOXIDANTS & REDOX SIGNALING

Relationship Between Downregulation of miRNAs and Increase of Oxidative Stress in the Development of Diabetic Cardiac Dysfunction: Junctin as a Target Protein of miR-1

(2013) Samet Serdar Yildirim et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Mitochondria Damage in the Pathogenesis of Diabetic Retinopathy and in the Metabolic Memory Associated with its Continued Progression

(2013) Renu Kowluru   CURRENT MEDICINAL CHEMISTRY

MitomiRs delineating the intracellular localization of microRNAs at mitochondria

(2013) S. Bandiera et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative Stress and MicroRNAs in Vascular Diseases

(2013) Alessandra Magenta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial function and insulin secretion

(2013) Pierre Maechler   MOLECULAR AND CELLULAR ENDOCRINOLOGY

MicroRNA-106b induces mitochondrial dysfunction and insulin resistance in C2C12 myotubes by targeting mitofusin-2

(2013) Ying Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The role of weight loss and exercise in correcting skeletal muscle mitochondrial abnormalities in obesity, diabetes and aging

(2013) Frederico G.S. Toledo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Social Factors and Leukocyte DNA Methylation of Repetitive Sequences: The Multi-Ethnic Study of Atherosclerosis

(2013) Malavika A. Subramanyam et al.   PLoS One

MiR-184 regulates insulin secretion through repression of Slc25a22

(2013) Sumiyo Morita et al.   PeerJ

miR-141 as a regulator of the mitochondrial phosphate carrier (Slc25a3) in the type 1 diabetic heart

(2012) Walter A. Baseler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mitochondrial Metabolic Reprogramming Induced by Calorie Restriction

(2012) Alejandro Martin-Montalvo et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases

(2012) Sung-Jun Park et al.   CELL

Lipid-Induced Mitochondrial Stress and Insulin Action in Muscle

(2012) Deborah M. Muoio et al.   Cell Metabolism

Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle

(2012) Romain Barrès et al.   Cell Metabolism

Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes

(2012) M. D. Nitert et al.   DIABETES

Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

(2012) A. Galmozzi et al.   DIABETES

Micronutrient status and global DNA methylation in school-age children

(2012) Wei Perng et al.   Epigenetics

White blood cell global methylation and IL-6 promoter methylation in association with diet and lifestyle risk factors in a cancer-free population

(2012) Fang Fang Zhang et al.   Epigenetics

Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease

(2012) Carlos Jose Pirola et al.   GUT

Association of an Intensive Lifestyle Intervention With Remission of Type 2 Diabetes

(2012) Edward W. Gregg et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of regression from prediabetes to normal glucose regulation on long-term reduction in diabetes risk: results from the Diabetes Prevention Program Outcomes Study

(2012) Leigh Perreault et al.   LANCET

Systematic Analysis of Small RNAs Associated with Human Mitochondria by Deep Sequencing: Detailed Analysis of Mitochondrial Associated miRNA

(2012) Lakshmi Sripada et al.   PLoS One

Genome-Wide Analysis of DNA Methylation Differences in Muscle and Fat from Monozygotic Twins Discordant for Type 2 Diabetes

(2012) Rasmus Ribel-Madsen et al.   PLoS One

Linking mitochondrial bioenergetics to insulin resistance via redox biology

(2012) Kelsey H. Fisher-Wellman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mitochondria and Oxidative Stress in the Cardiorenal Metabolic Syndrome

(2012) Annayya R. Aroor et al.   CardioRenal Medicine

HTR1B, ADIPOR1, PPARGC1A, and CYP19A1 and Obesity in a Cohort of Caucasians and African Americans: An Evaluation of Gene-Environment Interactions and Candidate Genes

(2011) Todd L. Edwards et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Fusion and Fission: Interlinked Processes Critical for Mitochondrial Health

(2011) David C. Chan   Annual Review of Genetics

Physical activity and global genomic DNA methylation in a cancer-free population

(2011) Fang Fang Zhang et al.   Epigenetics

Mitochondrial complex I impairment in leukocytes from type 2 diabetic patients

(2011) Antonio Hernandez-Mijares et al.   FREE RADICAL BIOLOGY AND MEDICINE

IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease

(2011) Marianna Sadagurski et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial dysfunction in patients with primary congenital insulin resistance

(2011) Alison Sleigh et al.   JOURNAL OF CLINICAL INVESTIGATION

Dietary Patterns Are Associated with Levels of Global Genomic DNA Methylation in a Cancer-Free Population

(2011) Fang Fang Zhang et al.   JOURNAL OF NUTRITION

The role of mitochondria in insulin resistance and type 2 diabetes mellitus

(2011) Julia Szendroedi et al.   Nature Reviews Endocrinology

DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria

(2011) Lisa S. Shock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men

(2010) A. C. Alibegovic et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects

(2010) Caroline Bolmeson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Foxo1 in hepatic lipid metabolism

(2010) Zhiyong Cheng et al.   CELL CYCLE

MicroRNA-15a positively regulates insulin synthesis by inhibiting uncoupling protein-2 expression

(2010) Liang-Liang Sun et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes

(2010) Mary-Elizabeth Patti et al.   ENDOCRINE REVIEWS

Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: Impact of liver methylation of the peroxisome proliferator-activated receptor γ coactivator 1α promoter

(2010) Silvia Sookoian et al.   HEPATOLOGY

Deoxyribonucleic Acid Methylation and Gene Expression ofPPARGC1Ain Human Muscle Is Influenced by High-Fat Overfeeding in a Birth-Weight-Dependent Manner

(2010) Charlotte Brøns et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Methylation of TFAM gene promoter in peripheral white blood cells is associated with insulin resistance in adolescents

(2010) Carolina Gemma et al.   MOLECULAR GENETICS AND METABOLISM

Building a multiple modality, theory-based physical activity intervention: The development of CardiACTION

(2010) Paul A. Estabrooks et al.   PSYCHOLOGY OF SPORT AND EXERCISE

Insulin signaling meets mitochondria in metabolism

(2010) Zhiyong Cheng et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes

(2010) Iain J Gallagher et al.   Genome Medicine

Nuclear transcription factors in mammalian mitochondria

(2010) Sarah Leigh-Brown et al.   GENOME BIOLOGY

Mitochondrial (Dys)function in Adipocyte (De)differentiation and Systemic Metabolic Alterations

(2009) Aurélia De Pauw et al.   AMERICAN JOURNAL OF PATHOLOGY

Non-CpG Methylation of the PGC-1α Promoter through DNMT3B Controls Mitochondrial Density

(2009) Romain Barrès et al.   Cell Metabolism

Subjects With Early-Onset Type 2 Diabetes Show Defective Activation of the Skeletal Muscle PGC-1 /Mitofusin-2 Regulatory Pathway in Response to Physical Activity

(2009) M. I. Hernandez-Alvarez et al.   DIABETES CARE

Legume-, Fish-, or High-Protein-Based Hypocaloric Diets: Effects on Weight Loss and Mitochondrial Oxidation in Obese Men

(2009) Itziar Abete et al.   JOURNAL OF MEDICINAL FOOD

Foxo1 integrates insulin signaling with mitochondrial function in the liver

(2009) Zhiyong Cheng et al.   NATURE MEDICINE

Maternal Pregestational BMI Is Associated With Methylation of thePPARGC1APromoter in Newborns

(2009) Carolina Gemma et al.   Obesity

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle

(2008) T. Rönn et al.   DIABETOLOGIA

Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion

(2008) C. Ling et al.   DIABETOLOGIA

In Vitro Evidence Suggests That miR-133a-mediated Regulation of Uncoupling Protein 2 (UCP2) Is an Indispensable Step in Myogenic Differentiation

(2008) Xi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Decreased Mitochondrial DNA Content Is Related to Insulin Resistance in Adolescents

(2008) Tomas F. Gianotti et al.   Obesity