DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute

The prokaryotic Argonaute proteins enhance homology sequence-directed recombination in bacteria

(2019) Lei Fu et al.   NUCLEIC ACIDS RESEARCH

Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA

(2018) Yiwei Liu et al.   Cell Reports

Cas9 versus Cas12a/Cpf1: Structure-function comparisons and implications for genome editing

(2018) Daan C. Swarts et al.   Wiley Interdisciplinary Reviews-RNA

CRISPR-Cas guides the future of genetic engineering

(2018) Gavin J. Knott et al.   SCIENCE

Autonomous Generation and Loading of DNA Guides by Bacterial Argonaute

(2017) Daan C. Swarts et al.   MOLECULAR CELL

Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a

(2017) Daan C. Swarts et al.   MOLECULAR CELL

Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1

(2017) Takashi Yamano et al.   MOLECULAR CELL

Prokaryotic Argonaute proteins: novel genome-editing tools?

(2017) Jorrit W. Hegge et al.   NATURE REVIEWS MICROBIOLOGY

Why Argonaute is needed to make microRNA target search fast and reliable

(2017) Misha Klein et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Programmable DNA-Guided Artificial Restriction Enzymes

(2017) Behnam Enghiad et al.   ACS Synthetic Biology

Guide-independent DNA cleavage by archaeal Argonaute from Methanocaldococcus jannaschii

(2017) Adrian Zander et al.   Nature Microbiology

Replications, ridicule and a recluse: the controversy over NgAgo gene-editing intensifies

(2016) David Cyranoski   NATURE

DNA-guided genome editing using the Natronobacterium gregoryi Argonaute

(2016) Feng Gao et al.   NATURE BIOTECHNOLOGY

Cornerstones of CRISPR–Cas in drug discovery and therapy

(2016) Christof Fellmann et al.   NATURE REVIEWS DRUG DISCOVERY

A bacterial Argonaute with noncanonical guide RNA specificity

(2016) Emine Kaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advances in therapeutic CRISPR/Cas9 genome editing

(2016) Nataša Savić et al.   Translational Research

Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid Guides

(2015) William E. Salomon et al.   CELL

A Dynamic Search Process Underlies MicroRNA Targeting

(2015) Stanley D. Chandradoss et al.   CELL

Argonaute of the archaeon Pyrococcus furiosus is a DNA-guided nuclease that targets cognate DNA

(2015) Daan C. Swarts et al.   NUCLEIC ACIDS RESEARCH

Effects of Argonaute on Gene Expression in Thermus thermophilus

(2015) Daan C. Swarts et al.   PLoS One

Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets

(2015) Nicole T Schirle et al.   eLife

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

(2014) Carolin Anders et al.   NATURE

DNA-guided DNA interference by a prokaryotic Argonaute

(2014) Daan C. Swarts et al.   NATURE

The evolutionary journey of Argonaute proteins

(2014) Daan C Swarts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single-molecule FRET supports the two-state model of Argonaute action

(2014) Adrian Zander et al.   RNA Biology

Structural basis for microRNA targeting

(2014) N. T. Schirle et al.   SCIENCE

Model morphing and sequence assignment after molecular replacement

(2013) Thomas C. Terwilliger et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Bacterial Argonaute Samples the Transcriptome to Identify Foreign DNA

(2013) Ivan Olovnikov et al.   MOLECULAR CELL

Argonaute proteins: functional insights and emerging roles

(2013) Gunter Meister   NATURE REVIEWS GENETICS

Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage

(2013) G. Sheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eukaryotic Argonautes come into focus

(2013) Claus-D. Kuhn et al.   TRENDS IN BIOCHEMICAL SCIENCES

Argonaute Divides Its RNA Guide into Domains with Distinct Functions and RNA-Binding Properties

(2012) Liang Meng Wee et al.   CELL

ArabidopsisArgonaute MID domains use their nucleotide specificity loop to sort small RNAs

(2012) Filipp Frank et al.   EMBO JOURNAL

Structure of yeast Argonaute with guide RNA

(2012) Kotaro Nakanishi et al.   NATURE

Data processing and analysis with theautoPROCtoolbox

(2011) Clemens Vonrhein et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Many Faces of RNAi

(2011) René F. Ketting   DEVELOPMENTAL CELL

Features and development ofCoot

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Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2

(2010) Filipp Frank et al.   NATURE

Ancestral Roles of Small RNAs: An Ago-Centric Perspective

(2010) L. Joshua-Tor et al.   Cold Spring Harbor Perspectives in Biology

Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements

(2009) Kira S Makarova et al.   Biology Direct

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The RNA-induced Silencing Complex: A Versatile Gene-silencing Machine

(2009) Ashley J. Pratt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

(2009) Yanli Wang et al.   NATURE

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

(2008) Yanli Wang et al.   NATURE

Structure of the guide-strand-containing argonaute silencing complex

(2008) Yanli Wang et al.   NATURE

Origins and evolution of eukaryotic RNA interference

(2008) S SHABALINA et al.   TRENDS IN ECOLOGY & EVOLUTION

Argonaute proteins: key players in RNA silencing

(2007) Gyorgy Hutvagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY